PF3D7_0805700 serine/threonine protein kinase, FIKK family

Immunofluorescence localization of the P. falciparum FIKK kinase Fk8 in human red blood cells infected by P. falciparum, showing co-localization of Fk8 (red channel) with a nuclear stain (DAPI, blue) indicative of the presence of parasite within a host cell. Two representative fields are shown. PfFk8 colocalizes with the nucleic acid stain DAPI.

Lin BC, Harris DR, Kirkman LMD, Perez AM, Qian Y, Schermerhorn JT, Hong MY, Winston DS, Xu L, Lieber AM, Hamilton M, Brandt GS. The anthraquinone emodin inhibits the non-exported FIKK kinase from Plasmodium falciparum. Bioorg Chem. 2017 Sep 18;75:217-223.

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