Immunofluorescence assay (IFA) results showing the localization of PfPMIX (modified PfPMIX locus to insert loxP sites and a C-terminal Ty epitope tag inDiCre expressing parasites) relative to the microneme proteins PfAMA1, PfCyRPA, and PfRhopH3. Scale bar, 2 mm. PfPMIXTy only partially colocalized with the secreted proteins PfCyRPA (cysteine-rich protective antigen) and PfRhopH3 (high–molecular weight rhoptry protein 3) but not with PfAMA1.
Pino P, Caldelari R, Mukherjee B, Vahokoski J, Klages N, Maco B, Collins CR, Blackman MJ, Kursula I, Heussler V, Brochet M, Soldati-Favre D. A multistage antimalarial targets the plasmepsins IX and X essential for invasion and egress. Science. 2017 358(6362):522-528.
PubMed Article: A multistage antimalarial targets the plasmepsins IX and X essential for invasion and egress
Other associated proteins
PFID | Formal Annotation |
---|---|
PF3D7_0423800 | RH5-Ripr membrane anchoring protein cysteine-rich protective antigen |
PF3D7_1133400 | apical membrane antigen 1 |
PF3D7_1430200 | plasmepsin IX |