PF3D7_1133400 apical membrane antigen 1

Immunofluorescence assay (IFA) results showing the localization of PfPMIX (modified PfPMIX locus to insert loxP sites and a C-terminal Ty epitope tag inDiCre expressing parasites) relative to the microneme proteins PfAMA1, PfCyRPA, and PfRhopH3. Scale bar, 2 mm. PfPMIXTy only partially colocalized with the secreted proteins PfCyRPA (cysteine-rich protective antigen) and PfRhopH3 (high–molecular weight rhoptry protein 3) but not with PfAMA1.

Pino P, Caldelari R, Mukherjee B, Vahokoski J, Klages N, Maco B, Collins CR, Blackman MJ, Kursula I, Heussler V, Brochet M, Soldati-Favre D. A multistage antimalarial targets the plasmepsins IX and X essential for invasion and egress. Science. 2017 358(6362):522-528.

Other associated proteins

PFID Formal Annotation
PF3D7_0423800 RH5-Ripr membrane anchoring protein cysteine-rich protective antigen
PF3D7_0905400 high molecular weight rhoptry protein 3
PF3D7_1430200 plasmepsin IX