PF3D7_0930300 merozoite surface protein 1

IFA of PfShelph2-HA3 parasites using anti-HA and anti-MSP119 antibodies at different stages of the RBC cycle, i.e. ring, trophozoite, schizont and merozoite. Scale bar, 2 μm. PfShelph2-HA3 is not detected from ring stage to young schizont. Then, during late schizogony, when MSP119 gives either a peripheral schizont staining or labels the periphery of each merozoite during budding, PfShelph2-HA3 is found in discrete apical foci and remains detectable in free merozoites. In contrast, in newly re-invaded ring, evidenced by the persistent parasite membranestaining with MSP119, PfShelph2-HA3 staining disappears.

Miliu A, Lebrun M, Braun-Breton C, Lamarque MH. Shelph2, a bacterial-like phosphatase of the malaria parasite Plasmodium falciparum, is dispensable during asexual blood stage. PLoS One. 2017 Oct 26;12(10):e0187073.

Other associated proteins

PFID Formal Annotation
PF3D7_1206000 shewanella-like protein phosphatase 2