Upper panel: PhIL1-GFP expression pattern in ring, trophozoite and schizont stages. Lower panel: PhIL1 forms a novel protein complex, which includes GAP50 but is different from the glideosome. Co-localization of PhIL1-GFP and GAP50 in P. falciparum blood-stage schizont. PfPhIL1 and PfGAP50 co-localise in IMC with a Pearson’s correlation coefficient of 0.78. Scale bar = 5 μm. The PhIL1 and GAP50 signals significantly co-localised (Fig. 4b). Together, these results confirm the association of PhIL1 with known components of the IMC, and in particular interactions with select, but not all, components of the glideosome.
Saini E, Zeeshan M, Brady D, Pandey R, Kaiser G, Koreny L, Kumar P, Thakur V, Tatiya S, Katris NJ, Limenitakis RS, Kaur I, Green JL, Bottrill AR, Guttery DS, Waller RF, Heussler V, Holder AA, Mohmmed A, Malhotra P, Tewari R. Photosensitized INA-Labelled protein 1 (PhIL1) is novel component of the inner membrane complex and is required for Plasmodium parasite development. Sci Rep. 2017 7(1):15577
Other associated proteins
|PF3D7_0109000||photosensitized INA-labeled protein PHIL1|