PF3D7_1133400 apical membrane antigen 1

Phosphatidylinositol 4-monophosphate is found at the Golgi apparatus throughout the Plasmodium falciparum erythrocytic cycle. (A) The PHFAPP-3HA sensor

colocalises extensively with the Golgi marker Endoplasmic reticulum Retention Defective protein 2 (ERD2) in rings (a), trophozoites (Troph) (b), schizonts (Schiz) (c) and free merozoites (Mero) (d). Colocalisation experiments revealed that PHFAPP-3HA overlapped extensively with Golgi ERD2 throughout the erythrocytic cycle. IFAs performed with antibodies to Apical membrane antigen 1 (AMA1) and Erythrocyte binding antigen 175 (EBA175), markers of two different micronemal populations, failed to show any strong overlap with PHFAPP-3HA (Ca,b)

Ebrahimzadeh Z, Mukherjee A, Richard D. A map of the subcellular distribution of phosphoinositides in the erythrocytic cycle of the malaria parasite Plasmodium falciparum. Int J Parasitol. 2017 Nov 15. pii: S0020-7519(17)30322-3.

Other associated proteins

PFID Formal Annotation
PF3D7_0707300 rhoptry-associated membrane antigen
PF3D7_0731500 erythrocyte binding antigen-175
PF3D7_1116000 rhoptry neck protein 4
PF3D7_1353600 ER lumen protein retaining receptor