Subcellular fractionation of Orc2. Co-IFA showing the localization of PfOrc2C with another ORC protein fOrc1. PfOrc2 partially co-localizes with PfOrc1. Double labeling IFA with PfOrc1 showed partial co-localization in the early stages which supported bonafide nuclear localization of PfOrc2C

Sharma R, Sharma B, Gupta A, Dhar SK. Identification of a novel trafficking pathway exporting a replication protein to nucleus via classical secretory pathway in Plasmodium falciparum. Biochim Biophys Acta. 2018 Mar 7. [Epub ahead of print] PMID: 29524523.