PF3D7_0705300 mediator of RNA polymerase ii transcription subunit 10, putative

Expression pattern of PfOrc2 in different parasite stages. (A) IFA using antibodies against PfOrc2N showing a diffused extra-nuclear pattern (late ring and schizontstage have been shown respectively. (B) IFA showing the punctate localization PfOrc2C in different parasite stages (late trophozoite and schizont respectively) (Scale bar represents 2μm in each case).

Lower panel: Full length PfOrc2 protein is associated with the ER. IFA showing the co-localization of PfOrc2N and an ER marker PDI. This indicates that the full-length PfOrc2 is associated with the ER.

Sharma R, Sharma B, Gupta A, Dhar SK. Identification of a novel trafficking pathway exporting a replication protein to nucleus via classical secretory pathway in Plasmodium falciparum. Biochim Biophys Acta. 2018 Mar 7. [Epub ahead of print]

Other associated proteins

PFID Formal Annotation
PF3D7_0827900 protein disulfide isomerase