PF3D7_1118600 histone acetyltransferase

Intracellular localization of PfMYST. Immunofluorescence assay was performed with fixed smears from different stages of parasites as described in experimental procedures. Red signal shows localization of PfMYST while blue signal depicts DAPI stained nuclei. PfMYST is localized into parasitophorus vacuole in ring stage similar to PfRUVBL3 protein, however in trophozoite stage it showed distribution majorly in the nucleus. In schizont stage, PfMYST localized predominantly on periphery of the infected erythrocyte.

Sen U, Saxena H, Khurana J, Nayak A, Gupta A. Plasmodium falciparum RUVBL3 protein: a novel DNA modifying enzyme and an interacting partner of essential HAT protein MYST. Sci Rep. 2018 Jul 19;8(1):10917.