Co-localization of PfJ23 with PfSBP1 using immunofluorescence assays. Left panel: Expression analysis and co-localization patterns of PfJ23 with PfSBP1(A) and PfEMP1. Since PfJ23 and PF70 share a high degree of sequence conservation, they are likely to share a common function. Our interaction data on PfJ23 with ATS of PfEMP1 suggests that members of hypothetical 16 protein family may have converging roles in terms of PfEMP1 transport.

Kaur J, Kumar V, Singh AP, Singh V, Bisht A, Dube T, Panda JJ, Behl A, Mishra PC, Hora R. Plasmodium falciparum protein 'PfJ23' hosts distinct binding sites for major virulence factor 'PfEMP1' and Maurer's cleft marker 'PfSBP1'. Pathog Dis. 2018. [Epub ahead of print]