PF3D7_0414900 armadillo-domain containing rhoptry protein

Conditional disruption of ACβ expression. IFA showing localisation of ACβ-HA3 in close proximity to the rhoptry protein ARO (PF3D7_0414900) in schizonts, and ablation of expression by RAP treatment. Over 99% of all RAP-treated ACβ-HA:loxP schizonts examined by IFA were HA-negative in three independent experiments. Scale bar, 10 μm. ACβ, adenylyl cyclase beta; ARO, armadillo repeats only protein;

Patel A, Perrin AJ, Flynn HR, Bisson C, Withers-Martinez C, Treeck M, Flueck C, Nicastro G, Martin SR, Ramos A, Gilberger TW, Snijders AP, Blackman MJ, Baker DA. Cyclic AMP signalling controls key components of malaria parasite host cell invasion machinery. PLoS Biol. 2019 May 10;17(5):e3000264. PMID: 31075098

Other associated proteins

PFID Formal Annotation
PF3D7_0802600 Adenylyl cyclase, Acb