PF3D7_1133400 apical membrane antigen 1

Localization of PfPH2 in free merozoites. A, B IFA showing that PfPH2 does not colocalize with markers of the micronemes: PfAMA1 (secreted on the parasite surface in free merozoites), PfEBA175, and PfEBA140 (A) or of the rhoptry markers PfRON4, PfRAP1, PfRH1, and PfRH5 (B). Scale bar represents 5 lm. Blue: DAPI-stained nucleus. no strong colocalization could be seen between PfPH2 and any of the markers. the PfPH2 signal often seemed to be more apical (Fig EV3Aii and iii and B).

Ibrahimzadeh Z, Mukherjee A, Crochetière MÈ, Sergerie A, Amiar S, Thompson LA, Gagnon D, Gaumond D, Stahelin RV, Dacks JB, Richard D. A pan-apicomplexan phosphoinositide-binding protein acts in malarial microneme exocytosis. EMBO Rep. 2019 May 16. pii: e47102.

Other associated proteins

PFID Formal Annotation
PF3D7_0102200 ring-infected erythrocyte surface antigen
PF3D7_0402300 reticulocyte binding protein homologue 1 normocyte binding protein 1
PF3D7_0424100 reticulocyte binding protein homologue 5
PF3D7_0424200 reticulocyte binding protein homologue 4
PF3D7_0731500 erythrocyte binding antigen-175
PF3D7_1116000 rhoptry neck protein 4
PF3D7_1337700 phosphoinositide-binding protein ph2
PF3D7_1353600 ER lumen protein retaining receptor
PF3D7_1410400 rhoptry-associated protein 1