PF3D7_0929400 high molecular weight rhoptry protein 2

Plasmodium falciparum RASP2 expression and localisation in erythrocytic stage. a IFAs on PfRASP2-HA3 schizonts showing PfRASP2-HA3 with rhoptry markers. RON4, rhoptry neck, RhopH2, rhoptry bulb. c IFAs of PfRASP2 in free merozoites. c-terminal endogenous tagging of RASP2 shows that this protein is expressed later than the rhoptry neck marker PfRON4 and the rhoptry bulb marker PfRhopH2. Additionally, it co-localised with PfRON4 but only partially with PfRhopH2 (c).

Suarez C, Lentini G, Ramaswamy R, Maynadier M, Aquilini E, Berry-Sterkers L, Cipriano M, Chen AL, Bradley P, Striepen B, Boulanger MJ, Lebrun M. A lipid-binding protein mediates rhoptry discharge and invasion in Plasmodium falciparum and Toxoplasma gondii parasites. Nat Commun. 2019 10(1):4041

Other associated proteins

PFID Formal Annotation
PF3D7_0210600 cytosolically exposed rhoptry leaflet interacting protein, protein CERLI1
PF3D7_1116000 rhoptry neck protein 4
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