PfCCp proteins are expressed in gametocyte sexual stages. PfCCp expression patterns in mature gametocytes as determined by indirect immunofluorescence assay using mouse sera directed against PfCCp1 through PfCCp5 and PfFNPA. PfCCp1 through PfCCp3 show a punctuate pattern in mature gametocytes, whereas PfCCp4 is homogenously expressed in association with the parasite plasmalemma. PfCCp5 and PfFNPA proteins are predominantly localized at the poles of the gametocytes. PfCCp expression is shown in green (Alexa Fluor 488), while erythrocytes are highlighted in red (Evans Blue). The nuclei of gametocytes as well as of asexual parasites (arrow) are highlighted in blue (TOTO-3). Bar = 2 mm.
Scholz SM, Simon N, Lavazec C, Dude MA, Templeton TJ, Pradel G. PfCCp proteins of Plasmodium falciparum: gametocyte-specific expression and role in complement-mediated inhibition of exflagellation. Int J Parasitol. 2008 38(3-4):327-40. PMID: 17950739.
Other associated proteins
|PF3D7_0109100||LCCL domain-containing protein|
|PF3D7_1407000||LCCL domain-containing protein|
|PF3D7_1451600||LCCL domain-containing protein|
|PF3D7_1455800||LCCL domain-containing protein|
|PF3D7_1475500||LCCL domain-containing protein|