PF3D7_1218300 AP-2 complex subunit mu

Left: Localisation of AP-2μ-3xHA and Rab5B by immunoelectron microscopy Electron micrographs of vesicular colocalisation of AP-2μ-3xHA (18 nm gold particles) and Rab5B (12 nm gold particles) in developing trophozoites. N: nucleus; ER: endoplasmic reticulum; H: haemozoin; white arrowhead: AP-2μ at the nuclear membrane; black arrowhead: vesicles co-labelled for both proteins. Scale bar: 500 nm. Right: Localisation of AP-2μ-2xFKBPP-GFP and PDI by immunoelectron microscopy. Electron micrographs of vesicular colocalisation of AP-2μ-2xFKBP-GFP (18 nm gold particles) and PDI (12 nm gold particles) in developing trophozoites. N: nucleus; ER: endoplasmic reticulum; H: haemozoin; white arrowhead: AP-2μ at the nuclear membrane; black arrow: AP-2μ in vesicles; black arrowhead: AP-2μ at the ER. Scale bar: 500 nm.

Modification of an atypical clathrin-independent AP-2 adaptin complex of Plasmodium falciparum reduces susceptibility to artemisinin. Ryan C. Henrici, Rachel L. Edwards, Martin Zoltner, Donelly A. van Schalkwyk, Melissa N. Hart, Franziska Mohring, Robert W. Moon, Stephanie D. Nofal, Avnish Patel, Christian Flueck, David A. Baker, doi: https://doi.org/10.1101/621078

Other associated proteins

PFID Formal Annotation
PF3D7_0827900 protein disulfide isomerase
PF3D7_1310600 ras-related protein Rab-5B secretory complex protein 61 alpha
img