Representative IFA of PfERC-M9 parasites showing that tagged PfERC localized to the ER as shown with colocalization with the ER chaperone BiP in all asexual stages of the parasite. Phase-contrast (DIC [differential interference contrast]), anti-BiP antibody (green), anti-HA antibody (red), DAPI (blue), and fluorescence merge images are shown from left to right. Images representing colocalization between PfERC and BiP (indicated by asterisks) have been magnified and are shown in the insets. Abbreviations: R, rings; T, trophozoites; S, schizonts. Bar, 5 mm. Immunofluorescence microscopy showed that PfERC colocalized with the ER marker, PfBiP
Fierro MA, Asady B, Brooks CF, Cobb DW, Villegas A, Moreno SNJ, Muralidharan V. An Endoplasmic Reticulum CREC Family Protein Regulates the Egress Proteolytic Cascade in Malaria Parasites. mBio. 2020 Feb 25;11(1). pii: e03078-19.
Other associated proteins
|PF3D7_1108600||endoplasmic reticulum-resident calcium binding protein|