Subcellular localization of PfRbAp46/48. Intracellular localization of PfRbAp46/48 by immunofluorescence assay in different stages of IDC (ring, trophozoite, and schizont) using pre-immune (a) and immune sera (b), respectively. DAPI was used to stain the parasite DNA (blue). Bar, 2 mm. PfRbAp46/48 localization results are in coordination with Gupta et all localization reports of largest subunit of the PfCAF-1 complex i.e., PfCAF-1p150, thus highlights co-localization of both the proteins. They showed that PfCAF-1p150 localizes to the nucleus in all the IDC stages and forms punctuate foci around the nucleus.

Kaushik M, Nehra A, Gakhar SK, Gill SS, Gill R. The multifaceted histone chaperone RbAp46/48 in Plasmodium falciparum: structural insights, production, and characterization. Parasitol Res. 2020 May 4.