Association between RhopH2 and CLAG3 revealed by imaging tandem-labeled cells. (C) Live-cell images of C3R2-DKI-infected cells at the indicated time points after invasion. RhopH2 and CLAG3 colocalize within trophozoites (top row) and within rhoptries of mature schizonts (other rows). Right panels, corresponding line scans. The results are representative of >80 cells imaged from at least eight experiments. Using imaging to track the movement of both proteins within individual parasites at various intracellular parasite stages and established that these proteins colocalize at all examined stages within the infected erythrocyte.
Ahmad M, Manzella-Lapeira J, Saggu G, Ito D, Brzostowski JA, Desai SA. Live-Cell FRET Reveals that Malaria Nutrient Channel Proteins CLAG3 and RhopH2 Remain Associated throughout Their Tortuous Trafficking. mBio. 2020 11(5):e01354-20.
Other associated proteins
|PF3D7_0929400||high molecular weight rhoptry protein 2|