A DegP2-inducible mutant constructed using the U1 system. Staining for the HA tag appended to the DegP2 cKD locus showed the expected localization of the protein to the mitochondrion. Individual parasites are visualized by staining for CDPK1. Scale bar is 5 μm.

Harding CR, Sidik SM, Petrova B, Gnädig NF, Okombo J, Herneisen AL, Ward KE, Markus BM, Boydston EA, Fidock DA, Lourido S. Genetic screens reveal a central role for heme metabolism in artemisinin susceptibility. Nat Commun. 2020 11(1):4813..