PfELC is essential for parasite invasion of the red blood cell. Representative immunofluorescence assays (IFAs) of schizont and ring-stage parasites co-labeled with the IMC marker GAP45. Peripheral staining is lost after treatment with rapamycin and a diffuse/punctate pattern is seen with anti-cMyc antibodies.

Moussaoui D, Robblee JP, Auguin D, Krementsova EB, Haase S, Blake TC, Baum J, Robert-Paganin J, Trybus KM, Houdusse A. Full-length Plasmodium falciparum myosin A and essential light chain PfELC structures provide new anti-malarial targets. Elife. 2020 Oct 13;9:e60581