Immunofluorescence was performed on the developing schizonts from the above treatments and probed with anti HA (Red), Anti H3K4Me3 (Green) and stained the nucleus with DAPI (White). The Perinuclear staining in the control treated samples for PfRFC1 was not observed in the cells subjected to genotoxic stress. White arrows indicate regions where PfRFC1 and H3K4Me3 do not co-localize.

Sheriff O, Yaw A, Lai SK, Loo HL, Sze SK, Preiser PR. Plasmodium falciparum replication factor C subunit 1 is involved in genotoxic stress response. Cell Microbiol. 2020 11:e13277.