Apicortin mediated tubulin polymerization and stabilization of parasite microtubules. Reduced expression of apicortin (green channel) and diffuse staining of α-tubulin-I (red channel) in parasites infecting miR-197 loaded erythrocytes. Scale bar represents distance of 5 μm. On the basis of these results, it can be inferred that Plasmodium vapicortin plays critical role in microtubular structure stabilization through the interaction with parasite tubulins.
Chakrabarti M, Joshi N, Kumari G, Singh P, Shoaib R, Munjal A, Kumar V, Behl A, Abid M, Garg S, Gupta S, Singh S. Interaction of Plasmodium falciparum apicortin with α- and β-tubulin is critical for parasite growth and survival. Sci Rep. 2021 11(1):4688.
PubMed Article: Interaction of Plasmodium falciparum apicortin with a- and ß-tubulin is critical for parasite growth and survival
Other associated proteins