Phosphoproteome
Data were collected from 5 different publications. Each publication is collor-coded and on the right side are indicated the articles in which a specific gene product is present - the more sources, the more reliable is the finding. The table geenrated from
Collins MO, Wright JC, Jones M, Rayner JC, Choudhary JS. Confident and sensitive phosphoproteomics using combinations of collision induced dissociation and electron transfer dissociation. J Proteomics. 2014 103C:1-14. PMID: 24657495
http://mpmp.huji.ac.il/maps/phosph_collins.html
Lasonder E, Green JL, Camarda G, Talabani H, Holder AA, Langsley G, Alano P. The Plasmodium falciparum schizont phosphoproteome reveals extensive phosphatidylinositol and cAMP-protein kinase A signaling. J Proteome Res. 2012 11(11):5323-37. PMID: 23025827
http://mpmp.huji.ac.il/maps/phosph_lasonder.html
Treeck M, Sanders JL, Elias JE, Boothroyd JC. The phosphoproteomes of Plasmodium falciparum and Toxoplasma gondii reveal unusual adaptations within and beyond the parasites' boundaries. Cell Host Microbe. 2011 10(4):410-9. PMID: 22018241
http://mpmp.huji.ac.il/maps/phosph_treeck.html
Pease BN, Huttlin EL, Jedrychowski MP, Talevich E, Harmon J, Dillman T, Kannan N, Doerig C, Chakrabarti R, Gygi SP, Chakrabarti D. Global analysis of protein expression and phosphorylation of three stages of Plasmodium falciparum intraerythrocytic develop
http://mpmp.huji.ac.il/maps/phosph_pease.html
Solyakov L, Halbert J, Alam MM, Semblat JP, Dorin-Semblat D, Reininger L, Bottrill AR, Mistry S, Abdi A, Fennell C, Holland Z, Demarta C, Bouza Y, Sicard et al. Global kinomic and phospho-proteomic analyses of the human malaria parasite Plasmodium falcipa
http://mpmp.huji.ac.il/maps/phosphopr.html
Wu Y, Nelson MM, Quaile A, Xia D, Wastling JM, Craig A. Identification of phosphorylated proteins in erythrocytes infected by the human malaria parasite Plasmodium falciparum. Malar J. 2009 May 18;8:105 PMID: 19450262;
Category PfID Annotation EC Transcript
36024 Amino acid metabolism PF3D7_0802000
glutamate dehydrogenase, putative 1.4.1.2
36267 PF3D7_1033100
S-adenosylmethionine decarboxylase/ornithine decarboxylase 4.1.1.17
36356 PF3D7_1129000
spermidine synthase 2.5.1.16
36360 PF3D7_1130000 phosphoacetylglucosamine mutase, putative 5.4.2.3
36744 PF3D7_1430700
NADP-specific glutamate dehydrogenase 1.4.1.4
36753 PF3D7_1435300
glutamate synthase [NADH], putative 1.4.1.14
35635 PF3D7_0204500
aspartate transaminase 2.6.1.1
35693 PF3D7_0309500 asparagine synthetase [glutamine-hydrolyzing], putative 6.3.5.4
35749 PF3D7_0405700
lysine decarboxylase, putative 4.1.1.18
35761 PF3D7_0413700 lysine decarboxylase-like protein, putative 4.1.1.18
35851 PF3D7_0520900
S-adenosyl-L-homocysteine hydrolase adenosylhomocysteinase 3.3.1.1
35893 PF3D7_0608800
ornithine aminotransferase 2.6.1.13
36159 PF3D7_0922200
S-adenosylmethionine synthetase 2.5.1.6
36488 PF3D7_1240000 3-hydroxyisobutyryl-CoA hydrolase, putative 4.2.1.17
36023 Carbohydrate metabolism PF3D7_0801800
mannose-6-phosphate isomerase, putative 5.3.1.8
36226 PF3D7_1012500 phosphoglucomutase, putative 5.4.2.2
36235 PF3D7_1015900
enolase 4.2.1.11
36329 PF3D7_1120100
phosphoglycerate mutase, putative 5.4.2.11
36573 PF3D7_1324900
L-lactate dehydrogenase 1.1.1.27
36729 PF3D7_1426700
phosphoenolpyruvate carboxylase 4.1.1.31
36754 PF3D7_1436000 glucose-6-phosphate isomerase 5.3.1.9
36768 PF3D7_1439900
triosephosphate isomerase 5.3.1.1
36783 PF3D7_1444800
fructose-bisphosphate aldolase 4.1.2.13
36805 PF3D7_1453800
glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase 1.1.1.49
36807 PF3D7_1454700
6-phosphogluconate dehydrogenase, decarboxylating, putative 1.1.1.44
36817 PF3D7_1462800
glyceraldehyde-3-phosphate dehydrogenase 1.2.1.12
36837 PF3D7_1471400 diacylglycerol kinase, putative 2.7.1.107
35695 PF3D7_0310300 phosphoglycerate mutase, putative 5.4.2.11
35702 PF3D7_0312400
glycogen synthase kinase 3 2.7.11.26
35912 PF3D7_0618500
malate dehydrogenase 1.1.1.37
35924 PF3D7_0624000
hexokinase 2.7.1.1
35928 PF3D7_0626800
pyruvate kinase 2.7.1.40
36141 PF3D7_0915400
ATP-dependent 6-phosphofructokinase 2.7.1.11
36160 PF3D7_0922500
phosphoglycerate kinase 2.7.2.3
36354 PF3D7_1128300 ATP-dependent 6-phosphofructokinase 2.7.1.11
36452 Cofactor metabolism PF3D7_1224000
GTP cyclohydrolase I 3.5.4.16
36650 PF3D7_1359100 riboflavin kinase, putative 2.7.1.26
36058 PF3D7_0810800
hydroxymethyldihydropterin pyrophosphokinase-dihydropteroate synthase 2.5.1.15
36572 PF3D7_1324800
dihydrofolate synthase/folylpolyglutamate synthase 6.3.2.12
36576 PF3D7_1327600
nicotinamide/nicotinic acid mononucleotide adenylyltransferase 2.7.7.18
36669 PF3D7_1367500
NADH-cytochrome b5 reductase, putative 1.6.2.2
36743 PF3D7_1430300 acid phosphatase, putative 3.1.3.2
36759 PF3D7_1437400
pantothenate kinase 2 2.7.1.33
35907 PF3D7_0616000
pyridoxal kinase 2.7.1.35
35918 PF3D7_0621200
pyridoxine biosynthesis protein PDX1
35931 PF3D7_0627500
protein DJ-1
36834 PF3D7_1469600
acetyl-coa carboxylase 6.3.4.14
35937 PF3D7_0629100
nicotinate phosphoribosyltransferase, putative 6.3.4.21
36019 Lipid metabolism PF3D7_0731600 acyl-CoA synthetase 6.2.1.3
36675 PF3D7_1372400 acyl-CoA synthetase 6.2.1.3
36394 PF3D7_1147500
protein farnesyltransferase subunit beta 2.5.1.58
36429 PF3D7_1212500
glycerol-3-phosphate 1-O-acyltransferase 2.3.1.15
36154 PF3D7_0920000 elongation of fatty acids protein, putative
36848 PF3D7_1476800 lysophospholipase, putative 3.1.1.5
35926 PF3D7_0625000
sphingomyelin synthase 1, putative 2.7.8.27
35993 PF3D7_0720700
phosphoinositide-binding protein px1
36162 PF3D7_0922900
3-oxoacyl-[acyl-carrier-protein] reductase 1.1.1.35
35933 PF3D7_0627800
acetyl-CoA synthetase 6.2.1.1
36054 PF3D7_0810000 acyl-CoA binding protein, putative
35652 PF3D7_0215300
acyl-CoA synthetase 6.2.1.3
35859 PF3D7_0525100 acyl-CoA synthetase 6.2.1.3
36402 PF3D7_1200700 acyl-CoA synthetase 6.2.1.3
35917 PF3D7_0619500 acyl-CoA synthetase 6.2.1.3
36484 PF3D7_1238800 acyl-CoA synthetase 6.2.1.3
36325 PF3D7_1119000 acyl-CoA-binding protein, putative
36193 PF3D7_1001600
exported lipase 2 3.1.1.23
35936 PF3D7_0628300
choline/ethanolaminephosphotransferase, putative 2.7.8.1
36553 PF3D7_1316600
CTP:phosphocholine cytidylyltransferase 2.7.7.15
36696 PF3D7_1409900
cytidine diphosphate-diacylglycerol synthase 2.7.7.41
36174 PF3D7_0930500 diacylglycerol kinase, putative 2.7.1.107
36343 PF3D7_1124600
ethanolamine kinase 2.7.1.82
36623 PF3D7_1347700
ethanolamine-phosphate cytidylyltransferase 2.7.7.14
36672 PF3D7_1369000 glycosylphosphatidylinositol anchor attachment 1 protein, putative
35676 PF3D7_0303200 lipin, putative 3.1.3.4
36155 PF3D7_0920800
inosine-5'-monophosphate dehydrogenase 1.1.1.205
36027 PF3D7_0802400 cyclin-like protein, putative
36552 PF3D7_1316100 inositol polyphosphate kinase, putative 2.7.1.151
35959 PF3D7_0705500
inositol-phosphate phosphatase, putative 3.1.3.25
35887 PF3D7_0605900 elongation of fatty acids protein, putative 6.2.1.3
35973 PF3D7_0709700
monoglyceride lipase 3.1.-.-
35974 PF3D7_0710200 conserved Plasmodium protein, unknown function
35826 PF3D7_0511800
inositol-3-phosphate synthase 5.5.1.4
35915 PF3D7_0618900 phosphatidylinositol N-acetylglucosaminyltransferase subunit GPI1 2.4.1.198
36342 PF3D7_1124100 beach domain-containing protein, putative
36364 PF3D7_1131800 oxysterol-binding protein, putative
35700 PF3D7_0311300 phosphatidylinositol 3- and 4-kinase, putative 2.7.1.67
35834 PF3D7_0515300
phosphatidylinositol 3-kinase 2.7.1.137
35820 PF3D7_0509800
phosphatidylinositol 4-kinase beta 2.7.1.67
35779 PF3D7_0419900
phosphatidylinositol 4-kinase, putative 2.7.1.67
35779 PF3D7_0419900
phosphatidylinositol 4-kinase, putative 2.7.1.67
36380 PF3D7_1141400 phosphatidylinositol N-acetylglucosaminyltransferase subunit H, putative 2.4.1.198
36629 PF3D7_1351000 phosphatidylinositol transfer protein, putative
35615 PF3D7_0110600
phosphatidylinositol-4-phosphate 5-kinase 2.7.1.68
36611 PF3D7_1343000
phosphoethanolamine N-methyltransferase 2.1.1.103
35993 PF3D7_0720700
phosphoinositide-binding protein px1
35953 PF3D7_0704400 phosphoinositide-binding protein, putative
35994 PF3D7_0721200 conserved Plasmodium protein, unknown function
36228 PF3D7_1013500
phosphoinositide-specific phospholipase C 3.1.4.11
35643 PF3D7_0209100
patatin-like phospholipase 1; PNPLA1 3.1.1.4
36069 PF3D7_0814400 phospholipase DDHD1, putative 3.1.1.32
35927 PF3D7_0626400 CRAL/TRIO /Sec14 domain containing protein
36483 PF3D7_1238600
sphingomyelin phosphodiesterase 3.1.4.12
36777 PF3D7_1442500
geranylgeranyl transferase type-2 subunit alpha 2.5.1.60
36486 Mucleotide metabolism PF3D7_1239000 HD superfamily phosphohydrolase protein 3.1.4.17
36564 PF3D7_1321500
3',5'-cyclic nucleotide phosphodiesterase beta 3.1.4.17
36028 PF3D7_0802600
Adenylyl cyclase, Acb 4.6.1.1
36217 PF3D7_1008900
adenylate kinase 2.7.4.3
36225 PF3D7_1012400