Malaria Parasite Metabolic Pathways
Drugs affecting pathway with unknown specific target
Glutathione metabolism map details
| PFID | PFID Old | Annotation | Formal Annotation | EC | Transcript |
|---|---|---|---|---|---|
PF3D7_0918900
|
PFI0925w | gamma-glutamylcysteine synthetase | gamma-glutamylcysteine synthetase | 6.3.2.2 |
|
|
PF3D7_0306300
|
PFC0271c | glutaredoxin | glutaredoxin 1 | 1.8.4.2 |
|
|
PF3D7_0606900
|
PFF0340c | glutaredoxin | glutaredoxin-like protein | 1.8.4.2 |
|
|
PF3D7_1419800
|
PF14_0192 | glutathione reductase | glutathione reductase | 1.8.1.7 |
|
|
PF3D7_1419300
|
PF14_0187 | glutathione S-transferase | glutathione S-transferase | 2.5.1.18 |
|
|
PF3D7_0512200
|
PFE0605c | glutathione synthetase | glutathione synthetase | 6.3.2.3 |
|
| PF3D7_0626100 | PFF1265w | glutathione-homocystine transhydrogenase | oxidoreductase, short-chain dehydrogenase family, putative | 1.8.4.1 |
|
|
PF3D7_0112200
|
PFA0590w | MRP | multidrug resistance-associated protein 1 MRP1 | 3.6.3.44 |
|
|
PF3D7_1229100
|
PFL1410c | MRP | multidrug resistance-associated protein 2, MRP2 | 3.6.3.44 |
|
|
PF3D7_0303600
|
PFC0166w | Plrx | plasmoredoxin |
|
|
|
PF3D7_1104400
|
PF11_0055 | thioredoxin-like mero protein | thioredoxin-like mero protein |
|
|
| PF3D7_0529100 | PFE1450c | thioredoxin-like protein, putative | thioredoxin-like protein, putative | ||
|
PF3D7_0717900
|
MAL7P1.88 | Trx | thioredoxin-like protein |
|
|
|
PF3D7_0916100
|
PFI0790w | Trx | thioredoxin 3 | ||
| PF3D7_0919300 | PFI0945w | Trx | thioredoxin-like protein 1, putative |
|
|
|
PF3D7_0925500
|
PFI1250w | Trx | thioredoxin-like protein 2 | ||
| PF3D7_1006600 | PF10_0066 | Trx | phosducin-like protein, putative |
|
|
| PF3D7_1230100 | PFL1450c | Trx | thioredoxin-like associated protein 1, putative |
|
|
|
PF3D7_1345100
|
MAL13P1.225 | Trx | thioredoxin 2 |
|
|
|
PF3D7_1457200
|
PF14_0545 | Trx | thioredoxin 1 |
Total number of related proteins: 2
| # | PFID | Formal Name |
|---|---|---|
| 1 |
PFA0590w
|
multidrug resistance-associated protein 1 MRP1 |
| 2 |
PFL1410c
|
multidrug resistance-associated protein 2, MRP2 |
Total number of related proteins: 1
| # | PFID | Formal Name |
|---|---|---|
| 1 |
PFC0166w
|
plasmoredoxin |
Total number of related proteins: 2
| # | PFID | Formal Name |
|---|---|---|
| 1 |
PFC0271c
|
glutaredoxin 1 |
| 2 |
PFF0340c
|
glutaredoxin-like protein |
Total number of related proteins: 1
| # | PFID | Formal Name |
|---|---|---|
| 1 |
PFE0605c
|
glutathione synthetase |
Total number of related proteins: 1
| # | PFID | Formal Name |
|---|---|---|
| 1 | PFE1450c | thioredoxin-like protein, putative |
Total number of related proteins: 1
| # | PFID | Formal Name |
|---|---|---|
| 1 | PFF1265w | oxidoreductase, short-chain dehydrogenase family, putative |
Total number of related proteins: 8
| # | PFID | Formal Name |
|---|---|---|
| 1 |
MAL7P1.88
|
thioredoxin-like protein |
| 2 |
PFI0790w
|
thioredoxin 3 |
| 3 | PFI0945w | thioredoxin-like protein 1, putative |
| 4 |
PFI1250w
|
thioredoxin-like protein 2 |
| 5 | PF10_0066 | phosducin-like protein, putative |
| 6 | PFL1450c | thioredoxin-like associated protein 1, putative |
| 7 |
MAL13P1.225
|
thioredoxin 2 |
| 8 |
PF14_0545
|
thioredoxin 1 |
Total number of related proteins: 1
| # | PFID | Formal Name |
|---|---|---|
| 1 |
PFI0925w
|
gamma-glutamylcysteine synthetase |
Total number of related proteins: 1
| # | PFID | Formal Name |
|---|---|---|
| 1 |
PF11_0055
|
thioredoxin-like mero protein |
Total number of related proteins: 1
| # | PFID | Formal Name |
|---|---|---|
| 1 |
PF14_0187
|
glutathione S-transferase |
Total number of related proteins: 1
| # | PFID | Formal Name |
|---|---|---|
| 1 |
PF14_0192
|
glutathione reductase |