idcUbiquitin conjugating factor E4 B Ubiquitin conjugating factor E4 B idc:Ariadne Ariadne Deubiquinating enzyme I ubiquitin carboxyl-terminal hydrolase ubiquitin carboxyl-terminal hydrolase Ubiquitin-protein ligase E3 ubiquitin specific protease ubiquitin carboxyl-terminal hydrolase Proteasome ATPase Ubiquitin polyubiquitin Ubiquitin activating enzyme E1 Ubiquitin-conjugating enzyme E2 a subunits 1-7 b subunits 1-7 Lid subunits Base subunits Proteasome activator p28 idc:ubiquitin carboxyl-terminal hydrolase idc:Deubiquinating enzyme I idc:ubiquitin carboxyl-terminal hydrolase idc:ubiquitin carboxyl-terminal hydrolase idc:ubiquitin specific protease idc:Ubiquitin activating enzyme E1 idc:Ubiquitin-conjugating enzyme E2 idc:Ubiquitin-protein ligase E3 idc:Proteasome ATPase idc:a subunits 1-7 idc:b subunits 1-7 idc:Lid subunits idc:Base subunits idc:Ubiquitin idc:Proteasome activator p28 idc:Proteasome regulatory component Rpn13 idc:Rpn13 Ddi1 Dsk2 RAD23 idc:Ddi1 idc:Dsk2 idc:RAD23 idc:p47 p47 proteasome assembly chaperone 4 idc:UMP1 UMP1


Online articles related to Proteasome-mediated proteolysis of ubiquinated proteins retrieved from PubMed

RX Drugs affecting pathway with unknown specific target

Drug Name PubMed Articles (year of publication)
6-Cyano-uridine 5′-OMonophosphate
adamantane-acetyl-(6-aminohexanoyl)(3)-(leucinyl)(3)-vinyl-(methyl)-sulfone
Argyrin f
Bortezomib
Carfilzomib
Dihydroartemisinin
Epomixine
Epoxomicin
Fellutamide
Gliotoxin
Lactacystin
Luzindole
Melatonin
MG132
Mg-132
Mln-273
Ormulide
Qsar) modeling, pharmacophore mapping
Salinosporamide a
YU101
Z-Leu-Leu-LeuB(OH)2

Proteasome-mediated proteolysis of ubiquinated proteins map details

PFID PFID Old Annotation EC Transcript
PF3D7_1306400 drugs PF13_0033 26S protease regulatory subunit 10B, putative; 26S proteasome AAA-ATPase subunit RPT4, putative 3.6.4.8 pie diagram
PF3D7_0413600 drugs PFD0665c 26S protease regulatory subunit 6B, putative; 26S proteasome AAA-ATPase subunit RPT3 3.6.4.8 pie diagram
PF3D7_0108000 PFA0400c a subunits 1-7 3.4.25.1 pie diagram
PF3D7_0317000 PFC0745c a subunits 1-7 3.4.25.1 pie diagram
PF3D7_0518300 drugs PFE0915c a subunits 1-7 3.4.25.1 pie diagram
PF3D7_0608500 PFF0420c a subunits 1-7 3.4.25.1 pie diagram
PF3D7_0727400 loop PF07_0112 a subunits 1-7 3.4.25.1 pie diagram
PF3D7_0803800 drugs MAL8P1.142 a subunits 1-7 3.4.25.1 pie diagram
PF3D7_0807500 MAL8P1.128 a subunits 1-7 3.4.25.1 pie diagram
PF3D7_0931800 PFI1545c a subunits 1-7 3.4.25.1 pie diagram
PF3D7_1011400 loop drugs PF10_0111 a subunits 1-7 3.4.25.1 pie diagram
PF3D7_1327900 PF13_0156a a subunits 1-7 3.4.25.1
PF3D7_1353800 PF13_0282 a subunits 1-7 3.4.25.1 pie diagram
PF3D7_1353900 MAL13P1.270 a subunits 1-7 3.4.25.1 pie diagram
PF3D7_1470900 drugs PF14_0676 a subunits 1-7 3.4.25.1 pie diagram
PF3D7_1474800 PF14_0716 a subunits 1-7 3.4.25.1 pie diagram
PF3D7_0303800 PFC0175w Ariadne pie diagram
PF3D7_0108000 PFA0400c b subunits 1-7 3.4.25.1 pie diagram
PF3D7_0518300 drugs PFE0915c b subunits 1-7 3.4.25.1 pie diagram
PF3D7_0803800 drugs MAL8P1.142 b subunits 1-7 3.4.25.1 pie diagram
PF3D7_0931800 PFI1545c b subunits 1-7 3.4.25.1 pie diagram
PF3D7_1011400 loop drugs PF10_0111 b subunits 1-7 3.4.25.1 pie diagram
PF3D7_1327900 PF13_0156a b subunits 1-7 3.4.25.1
PF3D7_1470900 drugs PF14_0676 b subunits 1-7 3.4.25.1 pie diagram
PF3D7_0205900 PFB0260w Base subunits pie diagram
PF3D7_0413600 drugs PFD0665c Base subunits 3.6.4.8 pie diagram
PF3D7_0807800 PF08_0109 Base subunits pie diagram
PF3D7_1008400 drugs PF10_0081 Base subunits 3.6.4.8 pie diagram
PF3D7_1130400 drugs PF11_0314 Base subunits 3.6.4.8 pie diagram
PF3D7_1248900 drugs PFL2345c Base subunits 3.6.4.8 pie diagram
PF3D7_1306400 drugs PF13_0033 Base subunits 3.6.4.8 pie diagram
PF3D7_1311500 drugs PF13_0063 Base subunits 3.6.4.8 pie diagram
PF3D7_1466300 PF14_0632 Base subunits 3.4.25.1 pie diagram
PF3D7_1409300 PF14_0090 Ddi1 3.4.23.- pie diagram
PF3D7_1117100 PF11_0177 Deubiquinating enzyme I 3.4.19.12 pie diagram
PF3D7_1113400 PF11_0142 Dsk2 pie diagram
PF3D7_0205400 PFB0240w Lid subunits pie diagram
PF3D7_0312300 PFC0520w Lid subunits 3.4.25.1 pie diagram
PF3D7_0317800 PFC0785c Lid subunits pie diagram
PF3D7_0912900 PFI0630w Lid subunits pie diagram
PF3D7_1017900 PF10_0174 Lid subunits 3.4.25.1 pie diagram
PF3D7_1030500 PF10_0298 Lid subunits 3.4.25.1 pie diagram
PF3D7_1129200 PF11_0303 Lid subunits pie diagram
PF3D7_1338100 MAL13P1.190 Lid subunits pie diagram
PF3D7_1368100 MAL13P1.343 Lid subunits pie diagram
PF3D7_1402300 loop drugs PF14_0025 Lid subunits pie diagram
PF3D7_0808300 MAL8P1.122 p47 pie diagram
PF3D7_1346800 PF13_0248 p47 pie diagram
PF3D7_1211800 PFL0585w polyubiquitin pie diagram
PF3D7_0907700 PFI0370c proteasome activator 28 subunit beta, putative pie diagram
PF3D7_0723600 PF07_0099 proteasome assembly chaperone 4 pie diagram
PF3D7_1008400 drugs PF10_0081 Proteasome ATPase 3.6.4.8 pie diagram
PF3D7_1130400 drugs PF11_0314 Proteasome ATPase 3.6.4.8 pie diagram
PF3D7_1248900 drugs PFL2345c Proteasome ATPase 3.6.4.8 pie diagram
PF3D7_1311500 drugs PF13_0063 Proteasome ATPase 3.6.4.8 pie diagram
PF3D7_0707400 drugs MAL7P1.209 Proteasome regulatory component pie diagram
PF3D7_1011700 PF10_0114 RAD23 pie diagram
PF3D7_1414000 PF14_0138 Rpn13 pie diagram
PF3D7_0815700 loop PF08_0067 Ubiquitin pie diagram
PF3D7_0818500 PF08_0056 Ubiquitin pie diagram
PF3D7_0922100 loop PFI1085w ubiquitin pie diagram
PF3D7_1132000 PF11_0329 ubiquitin pie diagram
PF3D7_1314800 loop PF13_0084 Ubiquitin pie diagram
PF3D7_1365900 loop PF13_0346 Ubiquitin pie diagram
PF3D7_0817000 MAL8P1.75 Ubiquitin activating enzyme E1 6.2.1.45 pie diagram
PF3D7_1225800 loop drugs PFL1245w Ubiquitin activating enzyme E1 6.2.1.45 pie diagram
PF3D7_1237000 drugs PFL1790w Ubiquitin activating enzyme E1 6.2.1.45 pie diagram
PF3D7_1333200 loop PF13_0182 Ubiquitin activating enzyme E1 6.2.1.45 pie diagram
PF3D7_1117100 PF11_0177 ubiquitin carboxyl-terminal hydrolase 3.4.19.12 pie diagram
PF3D7_1414700 PF14_0145 ubiquitin carboxyl-terminal hydrolase 3.4.19.12 pie diagram
PF3D7_1460400 drugs PF14_0576 ubiquitin carboxyl-terminal hydrolase 3.4.19.12 pie diagram
PF3D7_0104300 PFA0220w ubiquitin carboxyl-terminal hydrolase 1, putative 3.4.19.12 pie diagram
PF3D7_0413900 PFD0680c ubiquitin carboxyl-terminal hydrolase 13, putative 3.4.19.12 pie diagram
PF3D7_0527200 drugs PFE1355c ubiquitin carboxyl-terminal hydrolase 14 3.4.19.12 pie diagram
PF3D7_0516700 PFE0835w ubiquitin carboxyl-terminal hydrolase 2, putative 3.4.19.12 pie diagram
PF3D7_0722300 MAL7P1.120 ubiquitin carboxyl-terminal hydrolase, putative 3.4.19.12 pie diagram
PF3D7_0726500 MAL7P1.147 ubiquitin carboxyl-terminal hydrolase, putative 3.4.19.12 pie diagram
PF3D7_0826500 PF08_0020 Ubiquitin conjugating factor E4 B 6.3.2.19 pie diagram
PF3D7_0403500 PFD0165w ubiquitin specific protease 3.4.19.12 pie diagram
PF3D7_0904600 PFI0225w ubiquitin specific protease 3.4.19.12 pie diagram
PF3D7_0319300 PFC0855w Ubiquitin-conjugating enzyme E2 2.3.2.23 pie diagram
PF3D7_0527100 PFE1350c Ubiquitin-conjugating enzyme E2 6.3.2.19 pie diagram
PF3D7_0606200 PFF0305c Ubiquitin-conjugating enzyme E2 6.3.2.19 pie diagram
PF3D7_0915100 drugs PFI0740c Ubiquitin-conjugating enzyme E2 6.3.2.19 pie diagram
PF3D7_1033900 PF10_0330 Ubiquitin-conjugating enzyme E2 2.3.2.23 pie diagram
PF3D7_1243700 loop PFL2100w Ubiquitin-conjugating enzyme E2 6.3.2.19
PF3D7_1345500 loop MAL13P1.227 Ubiquitin-conjugating enzyme E2 6.3.2.19 pie diagram
PF3D7_0305700 PFC0255c ubiquitin-conjugating enzyme E2, putative 6.3.2.19 pie diagram
PF3D7_0812600 PF08_0085 ubiquitin-conjugating enzyme E2, putative 2.3.2.23 pie diagram
PF3D7_1412900 PF14_0128 ubiquitin-conjugating enzyme E2, putative 2.3.2.23 pie diagram
PF3D7_0312100 loop drugs PFC0510w Ubiquitin-protein ligase E3 6.3.2.19 pie diagram
PF3D7_0316900 loop PFC0740c Ubiquitin-protein ligase E3 6.3.2.19 pie diagram
PF3D7_0319100 PFC0845c Ubiquitin-protein ligase E3 6.3.2.19 pie diagram
PF3D7_0627300 PFF1325c Ubiquitin-protein ligase E3 6.3.2.19 pie diagram
PF3D7_0628100 loop PFF1365c Ubiquitin-protein ligase E3 6.3.2.19 pie diagram
PF3D7_0704600 MAL7P1.19 Ubiquitin-protein ligase E3 6.3.2.19 pie diagram
PF3D7_0707700 PF07_0026 Ubiquitin-protein ligase E3 6.3.2.19 pie diagram
PF3D7_0826100 MAL8P1.23 Ubiquitin-protein ligase E3 6.3.2.19 pie diagram
PF3D7_1119400 PF11_0201 Ubiquitin-protein ligase E3 6.3.2.19 pie diagram
PF3D7_0528000 PFE1395c UMP1 pie diagram