idc:Cytidylate kinase idc:Nucleoside-diphosphate kinase idc:dUTP diphosphatase idc:Nucleoside-diphosphate kinase idc:Cytidylate kinase idc:Orotidine-5'-phosphate decarboxylase idc:CTP synthase idc:TRX reductase Orotate phosphoribosyl transferase idc:Dihydroorotate dehydrogenase idc:Dihydroorotase idc:Aspartate carbamoyltransferase idc:Carbamoyl-P synthase idc:UTP-glucose-1-P uridylyltransferase idc:Serine hydroxymethyl-transferase idc:Ribonucleotide reductase idc:Nucleoside-P2 kinase idc:Nucleoside-P2 kinase idc:nucleoside-triphosphate-adenylate kinase idc:Ribonucleotide reductase idc:Ribonucleotide reductase nucleoside-triphosphate-adenylate kinase idc:Thymidylate synthetase idc:Carbonic anhydrase Carbonic anhydrase dTMP kinase Ribonucleotide reductase Ribonucleotide reductase Ribonucleotide reductase TRX reductase Serine hydroxymethyl-transferase CTP synthase Nucleoside-P2 kinase Nucleoside-P2 kinase Carbamoyl-P synthase TRX reductase dUTP diphosphatase dTMP kinase Nucleoside-diphosphate kinase Nucleoside-diphosphate kinase Cytidylate kinase Cytidylate kinase Orotidine-5'-phosphate decarboxylase Orotate phosphoribosyl transferase Dihydroorotate dehydrogenase Dihydroorotase Enhancer of rudimentary Aspartate carbamoyltransferase UTP-glucose-1-P uridylyltransferase Thymidylate synthetase idc:TRX reductase

Online articles related to Pyrimidine metabolism retrieved from PubMed

RX Drugs affecting pathway with unknown specific target

Drug Name PubMed Articles (year of publication)
5-fluorouracil
Dihydroartemisinin
DSM265
Methotrexate
MMV000563
MMV006188
MMV006820
MMV007875
MMV008294
MMV011099
MMV011259
MMV019670
MMV020439
MMV665940

Pyrimidine metabolism map details

PFID PFID Old Annotation EC Transcript
PF3D7_1344800 loop drugs MAL13P1.221 Aspartate carbamoyltransferase 2.1.3.2 pie diagram
PF3D7_1308200 drugs PF13_0044 Carbamoyl-P synthase 6.3.5.5 pie diagram
PF3D7_1140000 loop drugs PF11_0411 Carbonic anhydrase 4.2.1.1 pie diagram
PF3D7_1410200 loop drugs PF14_0100 CTP synthase 6.3.4.2 pie diagram
PF3D7_0111500 drugs PFA0555c Cytidylate kinase 2.7.4.14 pie diagram
PF3D7_1472900 drugs PF14_0697 Dihydroorotase 3.5.2.3 pie diagram
PF3D7_0603300 loop drugs PFF0160c dihydroorotate dehydrogenase 1.3.5.2 pie diagram
PF3D7_1251300 drugs PFL2465c dTMP kinase 2.7.4.9
PF3D7_1127100 drugs PF11_0282 dUTP diphosphatase 3.6.1.23 pie diagram
PF3D7_1037700 PF10_0370 Enhancer of rudimentary
PF3D7_0605600 drugs PFF0275c Nucleoside-diphosphate kinase 2.7.4.6 pie diagram
PF3D7_1366500 drugs PF13_0349 Nucleoside-diphosphate kinase 2.7.4.6 pie diagram
PF3D7_0605600 drugs PFF0275c Nucleoside-P2 kinase 2.7.4.6 pie diagram
PF3D7_1366500 drugs PF13_0349 Nucleoside-P2 kinase 2.7.4.6 pie diagram
PF3D7_0415600 loop drugs PFD0755c nucleoside-triphosphate-adenylate kinase 2.7.4.10 pie diagram
PF3D7_0512700 drugs PFE0630c Orotate phosphoribosyl transferase 2.4.2.10 pie diagram
PF3D7_1023200 drugs PF10_0225 Orotidine-5'-phosphate decarboxylase 4.1.1.23 pie diagram
PF3D7_1015800 loop drugs PF10_0154 ribonucleoside-diphosphate reductase small chain, putative 1.17.4.1 pie diagram
PF3D7_1405600 loop PF14_0053 ribonucleoside-diphosphate reductase small chain, putative 1.17.4.1 pie diagram
PF3D7_1437200 drugs PF14_0352 ribonucleoside-diphosphate reductase, large subunit, putative 1.17.4.1 pie diagram
PF3D7_1235600 loop drugs PFL1720w Serine hydroxymethyl-transferase 2.1.2.1 pie diagram
PF3D7_0417200 loop drugs PFD0830w Thymidylate synthetase 2.1.1.45 pie diagram
PF3D7_0923800 loop drugs PFI1170c TRX reductase 1.8.1.9 pie diagram
PF3D7_0517500 PFE0875c UTP-glucose-1-P uridylyltransferase 2.7.7.9 pie diagram