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Chloramphenicol - effect of drug on gene transcription |
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Siwo GH, Smith RS, Tan A, Button-Simons KA, Checkley LA, Ferdig MT. An integrative analysis of small molecule transcriptional responses in the human malaria parasite Plasmodium |
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Ratio = Transcript of treated vs untreated control
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PfID |
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Annotation |
Ratio |
EC |
Transcript |
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| 31942 |
PF3D7_0219400 |
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ribosome associated membrane protein RAMP4, putative |
0.628 |
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| 31943 |
PF3D7_1135000 |
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PQ-loop repeat-containing protein |
0.617 |
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| 31883 |
PF3D7_0922900 |
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3-oxoacyl-[acyl-carrier-protein] reductase |
1.811 |
1.1.1.35 |
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| 34040 |
PF3D7_1440700 |
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ap-3 complex subunit mu, putative |
0.672 |
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| 33631 |
PF3D7_0217300 |
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AP2S |
0.636 |
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| 31899 |
PF3D7_1250500 |
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AP-3 complex subunit sigma, putative |
0.681 |
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| 31859 |
PF3D7_0517800 |
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apicortin |
1.738 |
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| 31887 |
PF3D7_1026900 |
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biotin-protein ligase 1 |
1.891 |
6.4.1.2 |
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| 31920 |
PF3D7_1444200 |
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EF-hand calcium-binding domain-containing protein, putative |
1.804 |
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| 31900 |
PF3D7_1252200 |
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chitinase |
1.784 |
3.2.1.14 |
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| 31884 |
PF3D7_0933800 |
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tubulin delta chain, putative |
1.925 |
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| 31882 |
PF3D7_0919600 |
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added_product=dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit wbp1, putative |
0.651 |
2.4.1.119 |
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| 31911 |
PF3D7_1357300 |
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dynein light chain, putative |
1.994 |
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| 31881 |
PF3D7_0906400 |
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dynein intermediate light chain, putative |
1.902 |
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| 31917 |
PF3D7_1420800 |
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dynein light chain, putative |
2.021 |
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| 31846 |
PF3D7_0307300 |
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microtubule-associated protein RP/EB family, putative |
1.745 |
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| 31851 |
PF3D7_0402800 |
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erythrocyte membrane protein 1 (PfEMP1), pseudogene |
1.883 |
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| 31868 |
PF3D7_0712800 |
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erythrocyte membrane protein 1, PfEMP1 |
2.240 |
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| 31853 |
PF3D7_0421100 |
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erythrocyte membrane protein 1, PfEMP1 |
1.970 |
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| 31843 |
PF3D7_0300100 |
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erythrocyte membrane protein 1, PfEMP1 |
1.803 |
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| 31842 |
PF3D7_0223500 |
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erythrocyte membrane protein 1, PfEMP1 |
1.780 |
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| 31923 |
PF3D7_1455600 |
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ferlin, putative |
1.869 |
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| 31873 |
PF3D7_0813800 |
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GDP-mannose 4,6-dehydratase |
1.952 |
4.2.1.47 |
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| 31896 |
PF3D7_1212000 |
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glutathione peroxidase-like thioredoxin peroxidase |
0.651 |
1.11.1.9 |
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| 31895 |
PF3D7_1211100 |
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HSP20-like chaperone |
1.745 |
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| 31845 |
PF3D7_0304000 |
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inner membrane complex protein 1a, putative |
1.756 |
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| 31860 |
PF3D7_0602800 |
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jmjc domain-containing protein 2, putative |
0.679 |
1.14.11.27 |
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| 31880 |
PF3D7_0903800 |
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LCCL domain-containing protein |
1.745 |
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| 31922 |
PF3D7_1452100 |
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leucine-rich repeat protein |
0.656 |
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| 31909 |
PF3D7_1347800 |
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centrosomal protein CEP72, putative |
0.670 |
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| 31874 |
PF3D7_0815900 |
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dihydrolipoyl dehydrogenase, apicoplast |
1.786 |
1.1.1.35 |
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| 31906 |
PF3D7_1312000 |
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malonyl CoA-acyl carrier protein transacylase precursor |
1.779 |
2.3.1.39 |
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| 31944 |
PF3D7_0206900 |
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merozoite surface protein 5 |
0.666 |
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| 31891 |
PF3D7_1127300 |
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tRNA (guanine-N(7)-)-methyltransferase, putative |
0.656 |
2.1.1.33 |
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| 31925 |
PF3D7_1474100 |
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ribosomal protein L20, mitochondrial, putative |
0.678 |
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| 31862 |
PF3D7_0607100 |
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MYND finger protein, putative |
1.879 |
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| 31861 |
PF3D7_0605600 |
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nucleoside diphosphate kinase, putative |
1.736 |
2.7.4.6 |
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| 31849 |
PF3D7_0320400 |
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oocyst capsule protein cap380 |
1.889 |
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| 31915 |
PF3D7_1412000 |
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p1/s1 nuclease, putative |
1.799 |
3.1.30.1 |
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| 31876 |
PF3D7_0819400 |
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perforin-like protein 4 |
2.030 |
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| 31866 |
PF3D7_0700800 |
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Pfmc-2TM Maurer's cleft two transmembrane protein |
2.754 |
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| 31889 |
PF3D7_1100800 |
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Pfmc-2TM Maurer's cleft two transmembrane protein |
2.345 |
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| 31841 |
PF3D7_0222100 |
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Pfmc-2TM Maurer's cleft two transmembrane protein |
0.653 |
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| 31869 |
PF3D7_0713100 |
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Pfmc-2TM Maurer's cleft two transmembrane protein |
0.629 |
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| 31834 |
PF3D7_0101300 |
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Pfmc-2TM Maurer's cleft two transmembrane protein |
0.613 |
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| 31867 |
PF3D7_0701600 |
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Pfmc-2TM Maurer's cleft two transmembrane protein |
0.580 |
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| 31863 |
PF3D7_0629300 |
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phospholipase, putative phosphatidylcholine-sterol acyltransferase, putative |
1.920 |
2.3.1.43 |
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| 31855 |
PF3D7_0425100 |
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Plasmodium exported protein (hyp6), unknown function |
0.668 |
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| 31837 |
PF3D7_0201500 |
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Plasmodium exported protein (hyp9), unknown function |
0.637 |
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| 31929 |
PF3D7_1479200 |
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Plasmodium exported protein (PHISTa), unknown function |
2.052 |
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| 31904 |
PF3D7_1301500 |
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Plasmodium exported protein (PHISTa), unknown function |
0.588 |
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| 31901 |
PF3D7_1253100 |
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Plasmodium exported protein (PHISTa), unknown function |
0.493 |
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| 31926 |
PF3D7_1476300 |
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Plasmodium exported protein (PHISTb), unknown function |
2.227 |
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| 31854 |
PF3D7_0424800 |
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Plasmodium exported protein (PHISTb), unknown function |
0.686 |
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| 31877 |
PF3D7_0831000 |
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Plasmodium exported protein (PHISTb), unknown function gametocyte exported protein 9 |
0.643 |
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| 31835 |
PF3D7_0102300 |
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Plasmodium exported protein, unknown function |
0.622 |
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| 31905 |
PF3D7_1302300 |
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Plasmodium exported protein, unknown function |
0.616 |
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| 31927 |
PF3D7_1478300 |
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Plasmodium exported protein, unknown function, pseudogene |
1.748 |
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| 31928 |
PF3D7_1478400 |
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Plasmodium exported protein, unknown function, pseudogene |
0.679 |
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| 31910 |
PF3D7_1352900 |
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fam-f protein Plasmodium exported protein, unknown function |
1.839 |
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| 31872 |
PF3D7_0812900 |
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conserved plasmodium protein, unknown function |
2.055 |
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| 31921 |
PF3D7_1446400 |
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pyruvate dehydrogenase E1 component subunit beta |
1.738 |
1.2.4.1 |
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| 31852 |
PF3D7_0414300 |
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Rab5-interacting protein, putative |
0.676 |
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| 31918 |
PF3D7_1435100 |
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ribonuclease H2 subunit B, putative |
0.659 |
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| 31898 |
PF3D7_1240700 |
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rifin, pseudogene |
2.062 |
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| 31897 |
PF3D7_1219200 |
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rifin, pseudogene |
1.909 |
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| 31893 |
PF3D7_1150100 |
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rifin, pseudogene |
1.752 |
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| 31913 |
PF3D7_1400500 |
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rifin PIR protein |
2.350 |
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| 31903 |
PF3D7_1254800 |
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rifin |
2.233 |
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| 31864 |
PF3D7_0631800 |
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rifin |
2.208 |
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| 31850 |
PF3D7_0324500 |
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rifin |
1.974 |
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| 31870 |
PF3D7_0800500 |
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PIR protein rifin |
1.876 |
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| 31914 |
PF3D7_1400800 |
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rifin PIR protein |
1.854 |
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| 31892 |
PF3D7_1150000 |
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PIR protein rifin |
1.822 |
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| 31839 |
PF3D7_0212600 |
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secreted protein with altered thrombospondin repeat domain |
1.973 |
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| 31894 |
PF3D7_1206000 |
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shewanella-like protein phosphatase 2 |
1.849 |
3.1.3.16 |
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| 31908 |
PF3D7_1335900 |
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sporozoite surface protein 2 thrombospondin-related anonymous protein |
1.764 |
|
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 31871 |
PF3D7_0812300 |
|
|
sporozoite surface protein 3, putative |
2.060 |
|
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 31888 |
PF3D7_1100700 |
|
|
stevor, pseudogene |
2.326 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 31865 |
PF3D7_0700700 |
|
|
stevor, pseudogene |
2.153 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 31879 |
PF3D7_0832600 |
|
|
stevor PIR protein |
2.441 |
|
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 31902 |
PF3D7_1254300 |
|
|
PIR protein stevor |
1.897 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 31878 |
PF3D7_0832400 |
|
|
PIR protein stevor |
1.771 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 31912 |
PF3D7_1372800 |
|
|
stevor PIR protein |
0.574 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 31844 |
PF3D7_0300900 |
|
|
stevor |
1.782 |
|
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 31858 |
PF3D7_0510300 |
|
|
stripes inner membrane complex protein, putative |
1.829 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 31857 |
PF3D7_0507500 |
|
|
subtilisin-like protease 1 |
1.922 |
3.4.21.62 |
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 31856 |
PF3D7_0507200 |
|
|
subtilisin-like protease 3 |
2.126 |
3.4.21.62 |
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 31916 |
PF3D7_1419200 |
|
|
thioredoxin-like protein, putative |
0.666 |
|
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 31924 |
PF3D7_1469000 |
|
|
translation initiation factor IF-1 |
0.600 |
|
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 31838 |
PF3D7_0209600 |
|
|
transporter, putative |
1.940 |
|
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 38883 |
PF3D7_0104700 |
|
|
apicomplexan amino acid transporter apiat9, putative |
1.802 |
|
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 31848 |
PF3D7_0318800 |
|
|
triosephosphate isomerase, putative |
1.889 |
5.3.1.1 |
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 31933 |
PF3D7_1369800 |
|
|
tRNA Arginine |
0.632 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 31939 |
PF3D7_0529600 |
|
|
tRNA Arginine |
0.594 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 31932 |
PF3D7_1341000 |
|
|
tRNA Arginine |
0.522 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 31936 |
PF3D7_0403000 |
|
|
tRNA Asparagine |
0.575 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 31937 |
PF3D7_1370100 |
|
|
tRNA Cysteine |
0.454 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 31935 |
PF3D7_0312700 |
|
|
tRNA Isoleucine |
0.619 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 31938 |
PF3D7_1355400 |
|
|
tRNA Threonine |
0.590 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 31934 |
PF3D7_0702800 |
|
|
tRNA Tyrosine |
0.686 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 31847 |
PF3D7_0318700 |
|
|
conserved plasmodium protein, unknown function |
1.829 |
|
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 31907 |
PF3D7_1314800 |
|
|
ubiquitin-like protein, putative |
1.946 |
|
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 31930 |
PF3D7_0112400 |
|
|
rRNA |
0.683 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 31931 |
PF3D7_0725700 |
|
|
rRNA |
0.657 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 31940 |
PF3D7_0829700 |
|
|
ncRNA |
0.632 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 31941 |
PF3D7_1139400 |
|
|
ncRNA |
0.597 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 31890 |
PF3D7_1121400 |
|
|
WD repeat-containing protein, putative |
2.162 |
|
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 31885 |
PF3D7_1008600 |
|
|
zinc finger (ccch type) protein, putative |
1.805 |
|
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 31875 |
PF3D7_0818100 |
|
|
zinc finger protein, putative |
2.023 |
|
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 31886 |
PF3D7_1022300 |
|
|
ZIP domain-containing protein, putative, ZIPCO |
0.654 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|