Geldanamycin - effect of drug on gene transcription
Siwo GH, Smith RS, Tan A, Button-Simons KA, Checkley LA, Ferdig MT. An integrative analysis of small molecule transcriptional responses in the human malaria parasite Plasmodium falciparum. BMC Genomics. 2015 Dec 4;16:1030.PMID: 26637195
Ratio = Transcript of treated vs untreated control
PfID Annotation Ratio EC Transcript
32501 PF3D7_1451500 pre-mRNA-splicing factor CWF18, putative 1.481
32444 PF3D7_0713000 rifin PIR protein 1.306
32516 PF3D7_1418500 5S ribosomal RNA 1.304
32509 PF3D7_1479900 stevor PIR protein 1.254
32480 PF3D7_1146500 leucine-rich repeat protein 1.239
32400 PF3D7_0200400 stevor PIR protein 1.222
32517 PF3D7_0527800 tRNA Leucine 1.221
32430 PF3D7_0522500 50S ribosomal protein L17, apicoplast, putative 1.219
32440 PF3D7_0700800 Pfmc-2TM Maurer's cleft two transmembrane protein 1.218
32504 PF3D7_1476300 Plasmodium exported protein (PHISTb), unknown function 1.213
32506 PF3D7_1476900 Plasmodium exported protein, unknown function, pseudogene 1.210
32495 PF3D7_1372100 Plasmodium exported protein (PHISTb), unknown function gametocyte exported protein 4 1.207
32505 PF3D7_1476400 serine/threonine protein kinase, FIKK family, pseudogene 1.202 2.7.11.1
32513 PF3D7_0308400 U4 spliceosomal RNA 1.196
32421 PF3D7_0402700 rifin, pseudogene 1.195
32445 PF3D7_0731700 Plasmodium exported protein (hyp9), unknown function 1.195
32394 PF3D7_0101400 exported protein family 1, pseudogene 1.191
32474 PF3D7_1100800 Pfmc-2TM Maurer's cleft two transmembrane protein 1.190
32492 PF3D7_1371900 Plasmodium exported protein, unknown function 1.188
32414 PF3D7_0221700 Plasmodium exported protein, unknown function 1.186
32505 PF3D7_1476400 serine/threonine protein kinase, FIKK family, pseudogene 1.183 2.7.11.1
32435 PF3D7_0601700 Plasmodium exported protein (PHISTa), unknown function, pseudogene 1.182
32508 PF3D7_1479600 PIR protein rifin 1.177
32476 PF3D7_1114000 dynein light chain Tctex-type, putative 1.175
32494 PF3D7_1372000 Plasmodium exported protein (PHISTa), unknown function 1.173
32520 PF3D7_1369900 tRNA Tryptophan 1.169
32422 PF3D7_0412900 erythrocyte membrane protein 1, PfEMP1 1.157
32522 PF3D7_1139000 ncRNA 1.157
32418 PF3D7_0301500 Plasmodium exported protein, unknown function 1.151
32512 PF3D7_1213100 U1 spliceosomal RNA 1.150
32484 PF3D7_1252900 Plasmodium exported protein, unknown function 1.148
32441 PF3D7_0701600 Pfmc-2TM Maurer's cleft two transmembrane protein 1.148
32436 PF3D7_0632100 rifin 1.148
32472 PF3D7_1040900 PIR protein rifin 1.147
32475 PF3D7_1101400 rifin, pseudogene 1.142
32461 PF3D7_0935700 Plasmodium exported protein, unknown function 1.140
32488 PF3D7_1253800 Plasmodium exported protein (PHISTa), unknown function 1.140
32510 PF3D7_0112400 rRNA 1.139
32523 PF3D7_0620900 tRNA Leucine 1.139
32524 PF3D7_1213000 ncRNA 1.139
32397 PF3D7_0109100
LCCL domain-containing protein 1.135
32468 PF3D7_1031000
ookinete surface protein p25 1.134
32462 PF3D7_0936400
ring-exported protein 4 1.134
32514 PF3D7_1137000 U2 spliceosomal RNA 1.134
32486 PF3D7_1253300 Plasmodium exported protein (PHISTa), unknown function, pseudogene 1.134
32489 PF3D7_1300400 PIR protein rifin 1.130
32525 PF3D7_1418800 ncRNA 1.129
32423 PF3D7_0413300 rifin 1.128
32518 PF3D7_0514400 tRNA Phenylalanine 1.127
32463 PF3D7_0936700 lysophospholipase, putative 1.127 3.1.1.5
32431 PF3D7_0522900 zinc finger protein, putative 1.127
32511 PF3D7_1438200 tRNA Selenocysteine 1.126
32460 PF3D7_0930200 leucine-rich repeat protein 1.126
32507 PF3D7_1479500 PIR protein stevor 1.126
32526 PF3D7_0610300 ncRNA 1.124
32402 PF3D7_0200700 rifin PIR protein 1.122
32432 PF3D7_0600400
erythrocyte membrane protein 1, PfEMP1 1.122
32410 PF3D7_0219200 40S ribosomal protein S30 1.121
32477 PF3D7_1114200 GTPase-activating protein, putative 1.121
32443 PF3D7_0712500 rifin, pseudogene 1.118
32415 PF3D7_0222800 PIR protein stevor 1.118
32442 PF3D7_0712400 erythrocyte membrane protein 1, PfEMP1 1.118
32503 PF3D7_1469700 mediator of RNA polymerase II transcription subunit 6, putative 0.884
32429 PF3D7_0515900 NLI interacting factor-like phosphatase, putative 0.884
32412 PF3D7_0221000 Plasmodium exported protein, unknown function 0.884
32491 PF3D7_1367800 secreted ookinete protein, putative 0.884
32453 PF3D7_0832000 PIR protein stevor 0.884
32427 PF3D7_0500400 rifin 0.882
32449 PF3D7_0732900 PIR protein rifin 0.882
32437 PF3D7_0700200 PIR protein rifin 0.881
32479 PF3D7_1145700 bicoid-interacting protein BIN3, putative 0.881
32470 PF3D7_1040700 PIR protein rifin 0.881
32482 PF3D7_1149400 Plasmodium exported protein, unknown function 0.880
32424 PF3D7_0424800 Plasmodium exported protein (PHISTb), unknown function 0.879
32398 PF3D7_0113600 surface-associated interspersed protein 1.2 (SURFIN 1.2), pseudogene 0.879
32498 PF3D7_1432000 syntaxin, Qa-SNARE family 0.879
32428 PF3D7_0513400
GTP-binding protein yiha1, yiha1 0.877
32502 PF3D7_1469000
translation initiation factor IF-1 0.876
32467 PF3D7_1015700 tubulin binding cofactor c, putative 0.876
32527 PF3D7_0714700 tRNA Asparagine 0.876
32466 PF3D7_1001100 acyl-CoA binding protein, isoform 1, ACBP1 0.876
32451 PF3D7_0831700
heat shock protein 70 0.876
32497 PF3D7_1400800 rifin PIR protein 0.874
32457 PF3D7_0833400 rifin PIR protein 0.873
32450 PF3D7_0828500 translation initiation factor eIF-2B subunit alpha, putative 0.872
32396 PF3D7_0102600
serine/threonine protein kinase, FIKK family 0.872 2.7.11.1
32448 PF3D7_0732500 rifin PIR protein 0.870
32456 PF3D7_0832400 PIR protein stevor 0.870
32500 PF3D7_1446800
heme detoxification protein 0.870
32416 PF3D7_0223100
PIR protein rifin 0.869
32499 PF3D7_1438700 DNA primase small subunit 0.869 2.7.7.6
32434 PF3D7_0601200 Pfmc-2TM Maurer's cleft two transmembrane protein 0.865
32392 PF3D7_0100800 PIR protein rifin 0.865
32481 PF3D7_1148700
Plasmodium exported protein (PHISTc), unknown function gametocyte exported protein 12 0.865
32395 PF3D7_0101600 PIR protein rifin 0.863
32411 PF3D7_0220300 Plasmodium exported protein, unknown function 0.861
32473 PF3D7_1100700 stevor, pseudogene 0.860
32528 PF3D7_1252000 tRNA Glutamine 0.860
32458 PF3D7_0901100 rifin 0.858
32438 PF3D7_0700500 rifin 0.855
32405 PF3D7_0201700 DnaJ protein, putative 0.855
32404 PF3D7_0201600
PHISTb domain-containing RESA-like protein 1 0.854
32419 PF3D7_0301700
Plasmodium exported protein, unknown function 0.853
32483 PF3D7_1245100
kinesin-13, putative 0.851
32417 PF3D7_0301100 Plasmodium exported protein (hyp13), unknown function 0.849
32529 PF3D7_0706800 tRNA Threonine 0.849
32406 PF3D7_0201800
knob associated heat shock protein 40 0.847
32515 PF3D7_1341000 tRNA Arginine 0.846
32433 PF3D7_0600900 rifin, pseudogene 0.844
32471 PF3D7_1040800 PIR protein rifin 0.843
32496 PF3D7_1400400 PIR protein rifin 0.842
32469 PF3D7_1040000 rifin 0.841
32530 PF3D7_1370500 ncRNA 0.841
32420 PF3D7_0324400 rifin 0.840
32401 PF3D7_0200500 rifin PIR protein 0.837
32459 PF3D7_0901600 PIR protein stevor 0.834
32455 PF3D7_0832200
Plasmodium exported protein (PHISTa-like), unknown function 0.831
32478 PF3D7_1135000 PQ-loop repeat-containing protein 0.830
32403 PF3D7_0201500 Plasmodium exported protein (hyp9), unknown function 0.828
32521 PF3D7_1370100 tRNA Cysteine 0.825
32485 PF3D7_1253200 hypothetical protein 0.819
32464 PF3D7_1000500 rifin PIR protein 0.818
32413 PF3D7_0221100 Plasmodium exported protein, unknown function, pseudogene 0.812
32409 PF3D7_0202000
knob-associated histidine-rich protein 0.811
32531 PF3D7_0527700 tRNA Glutamic acid 0.804
32425 PF3D7_0425500 PIR protein stevor 0.800
32393 PF3D7_0101300
Pfmc-2TM Maurer's cleft two transmembrane protein 0.794
32407 PF3D7_0201900
erythrocyte membrane protein 3 0.785
32399 PF3D7_0114100
Pfmc-2TM Maurer's cleft two transmembrane protein 0.781
32519 PF3D7_0730700 tRNA Threonine 0.768
32465 PF3D7_1001000
chondroitin sulfate a ligand; plasmodium exported protein (hyp12) 0.763
32454 PF3D7_0832100 rifin, pseudogene 0.732
32452 PF3D7_0831900 Plasmodium exported protein (PHIST), unknown function, pseudogene 0.715
32426 PF3D7_0425900
PIR protein rifin 0.713
32487 PF3D7_1253600 rifin, pseudogene 0.689
32490 PF3D7_1300900
PIR protein stevor 0.688
32447 PF3D7_0732400 PIR protein rifin 0.643
32439 PF3D7_0700600 Plasmodium exported protein, unknown function, pseudogene 0.625
32446 PF3D7_0732100 erythrocyte membrane protein 1 (PfEMP1), pseudogene 0.609
Online articles related to Geldanamycin - effect of drug on gene transcription retrieved from PubMed