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IMC (inner membrane complex) proteins |
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Ferreira JL, Heincke D, Wichers JS, Liffner B, Wilson DW, Gilberger TW. The Dynamic Roles of the Inner Membrane Complex in the Multiple Stages of the Malaria Parasite. Front Cell Infect Microbiol. 2021 10:611801. PMID: 33489940 |
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Short ID |
PfID |
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Annotation |
TM |
Functional domains |
EC# |
Transcript |
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ALV1/IMC1a |
PF3D7_0304000 |
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inner membrane complex protein 1a, putative |
No |
Alveolin repeat |
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ALV2/IMC1e |
PF3D7_0304100 |
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inner membrane complex protein 1e, putative |
No |
Alveolin repeat |
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ALV3/IMC1h |
F3D7_1221400 |
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No |
Alveolin repeat |
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ALV4/IMC1g |
PF3D7_0525800 |
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inner membrane complex protein 1g, putative |
No |
Alveolin repeat |
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ALV5/IMC1c |
PF3D7_1003600 |
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inner membrane complex protein 1c, putative |
No |
Alveolin repeat |
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ALV6/IMC1f |
PF3D7_1351700 |
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inner membrane complex protein 1f, putative |
No |
Alveolin repeat |
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ALV7/Pf77/ |
PF3D7_0621400 |
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Pf77 protein inner membrane complex protein 1j, putative |
No |
Alveolin repeat |
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IMC1b |
PF3D7_1141900 |
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inner membrane complex protein 1b, putative |
No |
Alveolin repeat |
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IMC1d |
PF3D7_0708600 |
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inner membrane complex protein 1d, putative |
No |
Alveolin repeat |
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IMC1i |
PF3D7_0823500 |
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inner membrane complex protein 1i |
No |
Alveolin repeat |
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IMC1k |
PF3D7_1341800 |
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conserved Plasmodium protein, unknown function |
No |
Alveolin repeat |
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IMC1l |
PF3D7_1417000 |
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inner membrane complex protein 1l, putative |
No |
Alveolin repeat |
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IMC1m |
PF3D7_1028900 |
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inner membrane complex protein 1m, putative |
Ye |
s Alveolin repea |
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ELC |
PF3D7_1017500 |
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myosin essential light chain ELC |
No |
EF Hand domain |
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GA |
PF3D7_0515700 |
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Yes |
None identified |
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GAP45 |
PF3D7_1222700 |
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glideosome-associated protein 45 |
No |
None identified |
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GAP50 |
PF3D7_0918000 |
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glideosome-associated protein 50 secreted acid phosphatase |
Yes |
None identified |
3.1.3.2 |
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GAPM1 |
PF3D7_1323700 |
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glideosome associated protein with multiple membrane spans 1 |
Yes |
None identified |
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GAPM2 |
PF3D7_0423500 |
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glideosome associated protein with multiple membrane spans 2 |
Yes |
None identified |
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GAPM3 |
PF3D7_1406800 |
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glideosome associated protein with multiple membrane spans 3 |
Yes |
None identified |
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MTIP |
PF3D7_1246400 |
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myosin a-tail interacting protein |
No |
EF-hand domain |
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MyoA |
PF3D7_1342600 |
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myosin A |
No |
Myosin |
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BCP1 |
PF3D7_1436200 |
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basal complex protein 1 BCP1 |
No |
None identified |
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BTP1 |
PF3D7_0611600 |
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basal complex transmembrane protein 1 |
Yes |
None identified |
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BTP2 |
PF3D7_0704100 |
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basal complex transmembrane protein 2 |
Yes |
None identified |
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CINCH |
PF3D7_0407800 |
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coordinator of nascent cell detachment CINCH |
No |
None identified |
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HADO/HAD2 |
PF3D7_1205200 |
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morn1-associated had phosphatase, putative |
No |
HAD phosphatase |
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Morn1 |
PF3D7_1031200 |
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MORN repeat-containing protein 1 |
No |
MORN repeats |
2.7.1.68 |
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ATR |
PF3D7_0410600 |
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armadillo-type repeat protein atrp |
No |
Armadillo repeats |
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Coronin |
PF3D7_1251200 |
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coronin |
No |
WD40 repeats |
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DHHC1 |
PF3D7_0303400 |
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palmitoyltransferase |
Ye |
DHHC Palmitoyltransferase, ankyrin repeats |
2.3.1.- |
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DHHC2 |
PF3D7_0609800 |
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Yes |
DHHC Palmitoyltransferase, palmitoylated |
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DHHC3 |
PF3D7_1121000 |
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palmitoyltransferase DHHC3 |
Yes |
DHHC Palmitoyltransferase |
2.3.1.- |
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DHHC9 |
PF3D7_1115900 |
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palmitoyltransferase DHHC9 |
Yes |
DHHC Palmitoyltransferase |
2.3.1.- |
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GAMER |
PF3D7_0805200 |
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IMC-associated apicomplexan protein, putative gamete release protein, putative |
No |
None identified |
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ISP1 |
PF3D7_1011000 |
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inner membrane complex sub-compartment protein 1 |
No |
None identified |
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ISP3 |
PF3D7_1460600 |
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inner membrane complex sub-compartment protein 3 |
No |
None identified |
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NIPA |
PF3D7_0522600 |
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magnesium transporter NIPA, putative |
Yes |
Magnesium transporter |
3.6.3.2 |
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NN |
PF3D7_1345600 |
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inner membrane complex protein |
No |
None identified |
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NN |
PF3D7_1445700 |
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conserved Plasmodium protein, unknown function |
No |
None identified |
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PhIL1 |
PF3D7_0109000 |
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photosensitized INA-labeled protein PHIL1 |
No |
None identified |
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PIP1 |
PF3D7_1355600 |
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phil1 interacting protein pip1 |
No |
None identified |
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PIP2 |
PF3D7_1431100 |
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PhIL1 interacting protein PIP2 |
No |
None identified |
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PIP3 |
PF3D7_1430800 |
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phil1 interacting protein pip3 |
No |
None Identified |
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SIP |
PF3D7_0510300 |
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stripes inner membrane complex protein, putative |
No |
None identified |
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IMC20 |
PF3D7_1447500 |
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inner membrane complex protein, putative |
No |
None identified |
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IMC27 |
PF3D7_0518900 |
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conserved Plasmodium protein, unknown function |
No |
None identified |
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FBXO1 |
PF3D7_0619700 |
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f-box protein fbxo1, putative |
No |
F-box domain Ba |
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AC5 |
PF3D7_0722900 |
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conserved Plasmodium protein, unknown function |
No |
None identified |
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ISC1 |
PF3D7_1341500 |
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inner membrane complex suture component, putative |
No |
Palmitoylated C |
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ISC3 |
PF3D7_1431900 |
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inner membrane complex suture component, putative |
Yes |
Choline transporter |
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MSC1b |
PF3D7_1407700 |
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conserved Plasmodium protein, unknown function |
No |
None identified |
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PP7/AC6 |
PF3D7_1423300 |
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serine/threonine protein phosphatase 7 |
No |
Serine/Theronine phosphatase, EF hand domains |
3.1.3.16 |
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A list of the currently identified IMC proteins in Plasmodium spp., along with the P. falciparum homologs of proteins that have been localized to the IMC in other apicomplexans. Proteins are grouped by location (blue, Alveolins; red, Glideosome; green, Basal complex; yellow, IMC) and ordered within groups by their name to emphasize proteins with potentially related functions/localization. In gray are Plasmodium falciparum homologs of IMC proteins identified in Toxoplasma gondii (Tg) but which have yet to be confirmed as IMC localized in Plasmodium spp. Transmembrane domain and functional domain data is based on predictions from PlasmoDB |
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