IMC (inner membrane complex) proteins
Ferreira JL, Heincke D, Wichers JS, Liffner B, Wilson DW, Gilberger TW. The Dynamic Roles of the Inner Membrane Complex in the Multiple Stages of the Malaria Parasite. Front Cell Infect Microbiol. 2021 10:611801. PMID: 33489940
Short ID PfID Annotation TM Functional domains EC# Transcript
ALV1/IMC1a PF3D7_0304000 inner membrane complex protein 1a, putative No Alveolin repeat
ALV2/IMC1e PF3D7_0304100 inner membrane complex protein 1e, putative No Alveolin repeat
ALV3/IMC1h F3D7_1221400 No Alveolin repeat
ALV4/IMC1g PF3D7_0525800
inner membrane complex protein 1g, putative No Alveolin repeat
ALV5/IMC1c PF3D7_1003600
inner membrane complex protein 1c, putative No Alveolin repeat
ALV6/IMC1f PF3D7_1351700 inner membrane complex protein 1f, putative No Alveolin repeat
ALV7/Pf77/ PF3D7_0621400 Pf77 protein inner membrane complex protein 1j, putative No Alveolin repeat
IMC1b PF3D7_1141900 inner membrane complex protein 1b, putative No Alveolin repeat
IMC1d PF3D7_0708600 inner membrane complex protein 1d, putative No Alveolin repeat
IMC1i PF3D7_0823500 inner membrane complex protein 1i No Alveolin repeat
IMC1k PF3D7_1341800 conserved Plasmodium protein, unknown function No Alveolin repeat
IMC1l PF3D7_1417000 inner membrane complex protein 1l, putative No Alveolin repeat
IMC1m PF3D7_1028900 inner membrane complex protein 1m, putative Ye s Alveolin repea
ELC PF3D7_1017500
myosin essential light chain ELC No EF Hand domain
GA PF3D7_0515700 Yes None identified
GAP45 PF3D7_1222700
glideosome-associated protein 45 No None identified
GAP50 PF3D7_0918000
glideosome-associated protein 50 secreted acid phosphatase Yes None identified 3.1.3.2
GAPM1 PF3D7_1323700
glideosome associated protein with multiple membrane spans 1 Yes None identified
GAPM2 PF3D7_0423500
glideosome associated protein with multiple membrane spans 2 Yes None identified
GAPM3 PF3D7_1406800
glideosome associated protein with multiple membrane spans 3 Yes None identified
MTIP PF3D7_1246400
myosin a-tail interacting protein No EF-hand domain
MyoA PF3D7_1342600
myosin A No Myosin
BCP1 PF3D7_1436200 basal complex protein 1 BCP1 No None identified
BTP1 PF3D7_0611600
basal complex transmembrane protein 1 Yes None identified
BTP2 PF3D7_0704100
basal complex transmembrane protein 2 Yes None identified
CINCH PF3D7_0407800
coordinator of nascent cell detachment CINCH No None identified
HADO/HAD2 PF3D7_1205200 morn1-associated had phosphatase, putative No HAD phosphatase
Morn1 PF3D7_1031200
MORN repeat-containing protein 1 No MORN repeats 2.7.1.68
ATR PF3D7_0410600
armadillo-type repeat protein atrp No Armadillo repeats
Coronin PF3D7_1251200 coronin No WD40 repeats
DHHC1 PF3D7_0303400
palmitoyltransferase Ye DHHC Palmitoyltransferase, ankyrin repeats 2.3.1.-
DHHC2 PF3D7_0609800 Yes DHHC Palmitoyltransferase, palmitoylated
DHHC3 PF3D7_1121000
palmitoyltransferase DHHC3 Yes DHHC Palmitoyltransferase 2.3.1.-
DHHC9 PF3D7_1115900
palmitoyltransferase DHHC9 Yes DHHC Palmitoyltransferase 2.3.1.-
GAMER PF3D7_0805200 IMC-associated apicomplexan protein, putative gamete release protein, putative No None identified
ISP1 PF3D7_1011000
inner membrane complex sub-compartment protein 1 No None identified
ISP3 PF3D7_1460600
inner membrane complex sub-compartment protein 3 No None identified
NIPA PF3D7_0522600
magnesium transporter NIPA, putative Yes Magnesium transporter 3.6.3.2
NN PF3D7_1345600
inner membrane complex protein No None identified
NN PF3D7_1445700 conserved Plasmodium protein, unknown function No None identified
PhIL1 PF3D7_0109000
photosensitized INA-labeled protein PHIL1 No None identified
PIP1 PF3D7_1355600
phil1 interacting protein pip1 No None identified
PIP2 PF3D7_1431100 PhIL1 interacting protein PIP2 No None identified
PIP3 PF3D7_1430800 phil1 interacting protein pip3 No None Identified
SIP PF3D7_0510300 stripes inner membrane complex protein, putative No None identified
IMC20 PF3D7_1447500 inner membrane complex protein, putative No None identified
IMC27 PF3D7_0518900 conserved Plasmodium protein, unknown function No None identified
FBXO1 PF3D7_0619700 f-box protein fbxo1, putative No F-box domain Ba
AC5 PF3D7_0722900 conserved Plasmodium protein, unknown function No None identified
ISC1 PF3D7_1341500 inner membrane complex suture component, putative No Palmitoylated C
ISC3 PF3D7_1431900 inner membrane complex suture component, putative Yes Choline transporter
MSC1b PF3D7_1407700 conserved Plasmodium protein, unknown function No None identified
PP7/AC6 PF3D7_1423300 serine/threonine protein phosphatase 7 No Serine/Theronine phosphatase, EF hand domains 3.1.3.16
A list of the currently identified IMC proteins in Plasmodium spp., along with the P. falciparum homologs of proteins that have been localized to the IMC in other apicomplexans. Proteins are grouped by location (blue, Alveolins; red, Glideosome; green, Basal complex; yellow, IMC) and ordered within groups by their name to emphasize proteins with potentially related functions/localization. In gray are Plasmodium falciparum homologs of IMC proteins identified in Toxoplasma gondii (Tg) but which have yet to be confirmed as IMC localized in Plasmodium spp. Transmembrane domain and functional domain data is based on predictions from PlasmoDB
Online articles related to IMC (inner membrane complex) proteins retrieved from PubMed