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Established and putative Maurer’s clefts proteins |
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Lanzer M, Wickert H, Krohne G, Vincensini L, Braun Breton C. Maurer's clefts: a novel multi-functiono oligol organelle in the cytoplasm of |
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Plasmodium falciparum-infected erythrocytes.Int J Parasitol. 2006 Jan;36(1):23-36; Authors' annotation |
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Gene ID |
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Protein description - authors' annotation |
Signal oligo peptide |
Transmembrane domain |
Host cell targeting signal oligo (postion/sequence) |
Stage-dependent transcript |
EC |
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Maurer’s clefts associated proteins |
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3950 |
Enzymes |
PF3D7_1414400 |
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serine/threonine protein phosphatase PP1 |
0 |
0 |
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3.1.3.16 |
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3959 |
PF3D7_1479000 |
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acyl-CoA synthetase |
1 |
0 |
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6.2.1.3 |
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3850 |
PF3D7_0312400 |
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glycogen synthase kinase 3 |
0 |
0 |
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2.7.11.26 |
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3895 |
PF3D7_0827900 |
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protein disulfide isomerase |
1 |
0 |
65/RLIPE |
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5.3.4.1 |
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3953 |
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PF3D7_1444800 |
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fructose-bisphosphate aldolase |
0 |
0 |
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4.1.2.13 |
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3952 |
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PF3D7_1439900 |
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triosephosphate isomerase |
0 |
0 |
21/KSLTN |
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5.3.1.1 |
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3956 |
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PF3D7_1462800 |
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glyceraldehyde-3-phosphate dehydrogenase |
0 |
0 |
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1.2.1.12 |
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25542 |
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PF3D7_1216200 |
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glycerol-3-phosphate dehydrogenase [NAD+], putative |
0 |
1 |
2/RNLFD |
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1.1.1.8 |
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3912 |
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PF3D7_1015900 |
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enolase |
0 |
1 |
11/REILD |
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4.2.1.11 |
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3874 |
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PF3D7_0626800 |
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pyruvate kinase |
0 |
0 |
24/RQILE |
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2.7.1.40 |
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3943 |
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PF3D7_1324900 |
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L-lactate dehydrogenase |
1 |
0 |
26/KNLGD |
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1.1.1.27 |
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3911 |
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PF3D7_1012400 |
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hypoxanthine-guanine phosphoribosyltransferase |
0 |
0 |
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2.4.2.8 |
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3910 |
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PF3D7_1008900 |
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adenylate kinase |
0 |
0 |
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2.7.4.3 |
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3864 |
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PF3D7_0513300 |
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purine nucleoside phosphorylase |
0 |
1 |
16/RHLKI |
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2.4.2.1 |
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3945 |
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PF3D7_1343000 |
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phosphoethanolamine N-methyltransferase |
0 |
0 |
16/KILSD |
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2.1.1.103 |
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3838 |
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PF3D7_0207500 |
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serine repeat antigen 6 |
1 |
0 |
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3.4.22.- |
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3839 |
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PF3D7_0207600 |
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serine repeat antigen 5 |
1 |
0 |
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3.4.22.- |
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3848 |
Protein trafic |
PF3D7_0303000 |
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N-ethylmaleimide-sensitive fusion protein |
0 |
0 |
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3.6.4.6 |
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3856 |
PF3D7_0416800 |
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small GTP-binding protein sar1 |
0 |
0 |
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3893 |
PF3D7_0822600 |
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protein transport protein SEC23 |
0 |
0 |
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3951 |
PF3D7_1437800 |
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41-2 protein antigen precursor trafficking protein particle complex subunit 5, putative |
1 |
0 |
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3862 |
PF3D7_0501300 |
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skeleton-binding protein 1 |
0 |
1 |
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3873 |
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PF3D7_0603400 |
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trophozoite exported protein 1 |
0 |
0 |
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14381 |
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PF3D7_0202200 |
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EMP1-trafficking protein |
1 |
1 |
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14376 |
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PF3D7_0731100 |
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gametocyte exported protein 11 EMP1-trafficking protein |
1 |
1 |
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14380 |
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PF3D7_1478600 |
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EMP1-trafficking protein |
0 |
1 |
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14375 |
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PF3D7_0730900 |
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EMP1-trafficking protein |
1 |
1 |
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14377 |
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PF3D7_1002100 |
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EMP1-trafficking protein |
1 |
1 |
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14378 |
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PF3D7_1302000 |
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EMP1-trafficking protein |
1 |
1 |
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3900 |
Merozoite proteins |
PF3D7_0929400 |
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high molecular weight rhoptry protein 2 |
1 |
1 |
158/KYLLD |
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3846 |
PF3D7_0302200 |
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cytoadherence linked asexual protein 3.2 |
1 |
0 |
50/KLLNE |
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3847 |
PF3D7_0302500 |
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cytoadherence linked asexual protein 3.1 |
1 |
0 |
77/KLILE |
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3901 |
PF3D7_0935800 |
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cytoadherence linked asexual protein 9 |
1 |
0 |
81/KILNE |
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3897 |
PF3D7_0905400 |
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high molecular weight rhoptry protein 3 |
1 |
2 |
? |
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3835 |
Protein exported to RBC membrane |
PF3D7_0201900 |
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erythrocyte membrane protein 3 |
1 |
0 |
60/RSLAQ |
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3933 |
PF3D7_1149000 |
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antigen 332, DBL-like protein |
0 |
0 |
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3917 |
PF3D7_1038400 |
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gametocyte-specific protein |
0 |
0 |
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3960 |
PfEMP1 |
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PfEMP1 |
0 |
1 |
KHLLD |
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3961 |
STEVOR |
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STEVOR |
0 |
1 |
48/RLLAQ |
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3962 |
RIFIN |
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RIFIN |
0 |
1 |
RSLCE |
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3963 |
SURFIN |
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SURFIN |
0 |
1 |
KTIIE |
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3836 |
PF3D7_0202000 |
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knob-associated histidine-rich protein |
1a |
0 |
54/RTLAQ |
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3947 |
PF3D7_1370300 |
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membrane associated histidine-rich protein |
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3866 |
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PF3D7_0525400 |
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G-protein coupled receptor, putative |
0 |
7 |
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3885 |
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PF3D7_0702400 |
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small exported membrane protein 1 |
0 |
1 |
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3909 |
Diverse or unknown function |
PF3D7_1001900 |
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Plasmodium exported protein (hyp16), unknown function |
0(1) |
2(1) |
87/RFLSE |
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3907 |
PF3D7_1001000 |
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chondroitin sulfate a ligand; plasmodium exported protein (hyp12) |
1 |
0 |
47/RLISE |
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3832 |
PF3D7_0114100 |
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Pfmc-2TM Maurer's cleft two transmembrane protein |
1 |
1 |
43/RMLAQ |
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3843 |
PF3D7_0222100 |
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Pfmc-2TM Maurer's cleft two transmembrane protein |
1 |
1 |
43/RMLAQ |
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3871 |
PF3D7_0601200 |
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Pfmc-2TM Maurer's cleft two transmembrane protein |
1 |
3 |
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3915 |
PF3D7_1033200 |
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early transcribed membrane protein 10.2 |
1 |
1 |
52/RNLIL |
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3837 |
PF3D7_0202500 |
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early transcribed membrane protein 2 |
1 |
1 |
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3849 |
PF3D7_0310400 |
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TVN-junction protein 1 parasite-infected erythrocyte surface protein |
1 |
0 |
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3861 |
PF3D7_0501200 |
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parasite-infected erythrocyte surface protein |
1 |
1 |
43/RTLAD |
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3854 |
PF3D7_0401800 |
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Plasmodium exported protein (PHISTb), unknown function |
1 |
2 |
46/RNLSE |
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14374 |
PF3D7_0532400 |
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lysine-rich membrane-associated PHISTb protein |
1 |
1 |
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14372 |
PF3D7_0201600 |
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PHISTb domain-containing RESA-like protein 1 |
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3902 |
PF3D7_0935900 |
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ring-exported protein 1 |
1 |
1 |
? |
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3903 |
PF3D7_0936000 |
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ring-exported protein 2 |
0 |
1 |
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3905 |
PF3D7_0936300 |
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ring-exported protein 3 |
1 |
1 |
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3906 |
PF3D7_0936400 |
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ring-exported protein 4 |
1 |
1 |
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3888 |
PF3D7_0717600 |
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inner membrane complex protein, putative |
0 |
0 |
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3840 |
PF3D7_0214100 |
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protein transport protein SEC31 |
0 |
0 |
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3852 |
PF3D7_0324100 |
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Pfmc-2TM Maurer's cleft two transmembrane protein |
1 |
1 |
43/RILAQ |
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3922 |
PF3D7_1100800 |
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Pfmc-2TM Maurer's cleft two transmembrane protein |
1 |
2 |
43/RMLAQ |
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3882 |
PF3D7_0701600 |
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Pfmc-2TM Maurer's cleft two transmembrane protein |
0 |
3 |
43/RMLAQ |
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3925 |
PF3D7_1101700 |
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Pfmc-2TM Maurer's cleft two transmembrane protein |
0 |
3 |
43/RMLAQ |
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3875 |
PF3D7_0631400 |
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Pfmc-2TM Maurer's cleft two transmembrane protein |
0 |
3 |
43/RMLAQ |
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3919 |
PF3D7_1039700 |
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Pfmc-2TM Maurer's cleft two transmembrane protein |
0 |
3 |
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3828 |
PF3D7_0101300 |
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Pfmc-2TM Maurer's cleft two transmembrane protein |
0 |
3 |
42/RMLAQ |
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3841 |
PF3D7_0221500 |
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Pfmc-2TM Maurer's cleft two transmembrane protein, pseudogene |
0 |
0 |
43/RMLAQ |
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3887 |
PF3D7_0713100 |
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Pfmc-2TM Maurer's cleft two transmembrane protein |
1 |
2 |
43/RMLAQ |
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3939 |
PF3D7_1240100 |
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early transcribed membrane protein 12 |
1 |
1 |
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3878 |
|
PF3D7_0700800 |
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|
Pfmc-2TM Maurer's cleft two transmembrane protein |
1 |
2 |
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14379 |
|
PF3D7_1334500 |
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|
MSP7-like protein |
0 |
1 |
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|
|
Putative Maurer's cleft proteins |
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|
3916 |
Enzymes and transporters |
PF3D7_1037300 |
|
|
ADP, ATP carrier protein 1, aac1 |
0 |
3 |
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3955 |
PF3D7_1456800 |
|
|
V-type H(+)-translocating pyrophosphatase, putative, VP1 |
1 |
15 |
52/KEIAS |
|
3.6.1.1 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
3891 |
Chaperones |
PF3D7_0818200 |
|
|
14-3-3 protein |
0 |
0 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
3930 |
PF3D7_1117700 |
|
|
GTP-binding nuclear protein RAN/TC4 |
|
0 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
3894 |
PF3D7_0826700 |
|
|
receptor for activated c kinase |
0 |
0 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
3932 |
PF3D7_1134000 |
|
|
PfHsp70-3 |
0 |
0 |
11/KILER |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
3892 |
PF3D7_0818900 |
|
|
PfHsp70-1 |
0 |
0 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
3886 |
PF3D7_0708400 |
|
|
heat shock protein 90 |
0 |
1 |
27/KEIFL |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
3899 |
PF3D7_0917900 |
|
|
PfHsp70-2 |
1 |
0 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
3860 |
PF3D7_0501100 |
|
|
co-chaperone j domain protein jdp |
1 |
0 |
60/RSLAE |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
3957 |
PVM proteins |
PF3D7_1471100 |
|
|
exported protein 2 |
1 |
0 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
3857 |
PF3D7_0423700 |
|
|
early transcribed membrane protein 4 |
1 |
1 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
3867 |
PF3D7_0532100 |
|
|
early transcribed membrane protein 5 |
1 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
3908 |
PF3D7_1001500 |
|
|
early transcribed membrane protein 10., ETRAMP10.1 |
1 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
3927 |
PF3D7_1102700 |
|
|
early transcribed membrane protein 11.1 |
0 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
3928 |
PF3D7_1102800 |
|
|
early transcribed membrane protein 11.2 |
1 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
3946 |
|
PF3D7_1353200 |
|
|
membrane associated histidine-rich protein 2 |
0 |
1 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
3937 |
Others |
PF3D7_1228600 |
|
|
merozoite surface protein 9 |
1 |
0 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
3913 |
PF3D7_1016300 |
|
|
glycophorin binding protein |
1 |
0 |
84/RILAE |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
3941 |
PF3D7_1301200 |
|
|
glycophorin binding protein |
0 |
1 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
3948 |
PF3D7_1401000 |
|
|
GBPH protein |
0 |
1 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
3944 |
PF3D7_1335100 |
|
|
merozoite surface protein 7 |
1 |
0 |
50/KNIVS |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
3863 |
PF3D7_0501500 |
|
|
rhoptry-associated protein 3 |
1 |
0 |
27/KALID |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
3931 |
PF3D7_1121600 |
|
|
parasitophorous vacuole membrane antigen QF 116 exported protein 1 circumsporozoite-related antigen |
1 |
1 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
3855 |
PF3D7_0406200 |
|
|
parasitophorous vacuole membrane protein s16; sexual stage-specific protein s16 |
1 |
1 |
5/KFIPS |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
3936 |
PF3D7_1222300 |
|
|
endoplasmin, putative |
1 |
1 |
25/RVLCD |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
3898 |
|
PF3D7_0911300 |
|
|
cysteine repeat modular protein 1 |
0 |
8 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
3889 |
|
PF3D7_0718300 |
|
|
cysteine repeat modular protein 2 |
2 |
8 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
3926 |
|
PF3D7_1101800 |
|
|
exported protein family 1 |
1 |
0 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
3829 |
|
PF3D7_0101400 |
|
|
exported protein family 1, pseudogene |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
3851 |
|
PF3D7_0324000 |
|
|
exported protein family 1 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
3918 |
|
PF3D7_1039600 |
|
|
exported protein family 1, pseudogene |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
3842 |
|
PF3D7_0222000 |
|
|
exported protein family 1 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
3883 |
|
PF3D7_0701700 |
|
|
exported protein family 1 |
2 |
0 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
3872 |
|
PF3D7_0601300 |
|
|
exported protein family 1 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
3831 |
|
PF3D7_0114000 |
|
|
exported protein family 1; MEC domain-containing protein |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
3876 |
|
PF3D7_0631500 |
|
|
Plasmodium exported protein (hyp4), unknown function exported protein family 3 |
1 |
1 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
3881 |
|
PF3D7_0701500 |
|
|
Plasmodium exported protein (hyp4), unknown function exported protein family 3 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
3920 |
|
PF3D7_1039800 |
|
|
Plasmodium exported protein (hyp4), unknown function exported protein family 3 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
3827 |
|
PF3D7_0101200 |
|
|
Plasmodium exported protein (hyp4), unknown function exported protein family 3 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
3844 |
|
PF3D7_0222200 |
|
|
Plasmodium exported protein (hyp4), unknown function exported protein family 3 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
3870 |
|
PF3D7_0601100 |
|
|
exported protein family 3 Plasmodium exported protein (hyp4), unknown function |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
3833 |
|
PF3D7_0114200 |
|
|
Plasmodium exported protein (hyp4), unknown function exported protein family 3 |
1 |
1 |
2/3 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
3924 |
|
PF3D7_1101600 |
|
|
exported protein family 3 Plasmodium exported protein (hyp4), unknown function |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
3826 |
|
PF3D7_0101100 |
|
|
exported protein family 4 Plasmodium exported protein (hyp5), unknown function |
0 |
2 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
3869 |
|
PF3D7_0601000 |
|
|
exported protein family 4 Plasmodium exported protein (hyp5), unknown function |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
3921 |
|
PF3D7_1039900 |
|
|
Plasmodium exported protein (hyp5), unknown function exported protein family 4 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
3853 |
|
PF3D7_0324300 |
|
|
Plasmodium exported protein (hyp5), unknown function exported protein family 4 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
3877 |
|
PF3D7_0631600 |
|
|
Plasmodium exported protein (hyp5), unknown function exported protein family 4 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
3923 |
|
PF3D7_1101500 |
|
|
Plasmodium exported protein (hyp5), unknown function exported protein family 4 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
3845 |
|
PF3D7_0222300 |
|
|
exported protein family 4, pseudogene |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
3880 |
|
PF3D7_0701400 |
|
|
exported protein family 4, pseudogene |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
29880 |
|
PF3D7_0114300 |
|
|
plasmodium exported protein (hyp5), unknown function, pseudogene |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
3858 |
Unknown function or localization |
PF3D7_0424600 |
|
|
plasmodium exported protein (phistb) |
0 |
1 |
86/RILSE |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
3940 |
PF3D7_1252700 |
|
|
Plasmodium exported protein (PHISTb), unknown function |
0 |
0 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
3884 |
PF3D7_0702100 |
|
|
Plasmodium exported protein (PHISTb), unknown function, pseudogene |
0 |
0 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
3879 |
PF3D7_0700900 |
|
|
RESA-like protein, pseudogene |
0 |
0 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
3830 |
PF3D7_0102200 |
|
|
ring-infected erythrocyte surface antigen |
0 |
0 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
33884 |
PF3D7_1104400 |
|
|
thioredoxin-like mero protein |
1 |
1 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
3934 |
PF3D7_1201000 |
|
|
Plasmodium exported protein (PHISTb), unknown function |
1 |
0 |
46/RILSS |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
3890 |
PF3D7_0731300 |
|
|
Plasmodium exported protein (PHISTb), unknown function |
1 |
0 |
52/RILSE |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
3859 |
PF3D7_0501000 |
|
|
Plasmodium exported protein, unknown function |
1 |
0 |
89/RVLAE |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
3868 |
PF3D7_0532300 |
|
|
Plasmodium exported protein (PHISTb), unknown function |
0 |
1 |
88/RNLCE |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
3865 |
PF3D7_0515200 |
|
|
conserved Plasmodium protein, unknown function |
0 |
1 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
3904 |
PF3D7_0936100 |
|
|
early transcribed membrane protein |
1 |
2 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
3896 |
PF3D7_0829600 |
|
|
early transcribed membrane protein 8 |
1 |
2 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
3914 |
PF3D7_1016900 |
|
|
early transcribed membrane protein 10.3, UIS4 |
1 |
2 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
3958 |
PF3D7_1476100 |
|
|
early transcribed membrane protein 14.2 |
1 |
2 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
3949 |
PF3D7_1401400 |
|
|
early transcribed membrane protein 14.1 |
1 |
2 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
3942 |
PF3D7_1302200 |
|
|
early transcribed membrane protein 13 |
1 |
1 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
3954 |
PF3D7_1445700 |
|
|
conserved Plasmodium protein, unknown function |
0 |
0 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
3938 |
PF3D7_1229400 |
|
|
macrophage migration inhibitory factor |
0 |
0 |
|
|
5.3.2.1 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|