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Methyl Methanesulfonate - effect of drug on gene transcription |
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Siwo GH, Smith RS, Tan A, Button-Simons KA, Checkley LA, Ferdig MT. An integrative analysis of small molecule transcriptional responses in the human malaria parasite Plasmodium falciparum. BMC Genomics. 2015 Dec 4;16:1030.PMID: 26637195 |
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Ratio = Transcript of treated vs untreated control |
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PfID |
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Annotation |
Ratio |
EC |
Transcript |
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| 32965 |
PF3D7_1348800 |
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E1-E2 ATPase, putative |
1.827 |
3.6.3.8 |
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| 32961 |
PF3D7_1143200 |
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DnaJ protein, putative |
1.769 |
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| 32954 |
PF3D7_1022300 |
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ZIP domain-containing protein, putative, ZIPCO |
1.763 |
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| 32951 |
PF3D7_0718300 |
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cysteine repeat modular protein 2 |
1.751 |
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| 32958 |
PF3D7_1039100 |
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DnaJ protein, putative, pseudogene? MEC domain-containing protein |
1.705 |
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| 32969 |
PF3D7_1469000 |
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translation initiation factor IF-1 |
1.701 |
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| 32971 |
PF3D7_1477800 |
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acyl-CoA binding protein |
1.672 |
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| 32959 |
PF3D7_1102200 |
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erythrocyte cytoskeleton-interacting j protein |
1.657 |
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| 32970 |
PF3D7_1475400 |
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cysteine repeat modular protein 4 |
1.647 |
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| 32946 |
PF3D7_0105300 |
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cyclase-associated protein |
1.637 |
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| 32949 |
PF3D7_0522500 |
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50S ribosomal protein L17, apicoplast, putative |
1.610 |
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| 32953 |
PF3D7_0905300 |
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dynein heavy chain, putative |
1.584 |
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| 32947 |
PF3D7_0220400 |
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DnaJ protein, putative, pseudogene; MEC domain-containing protein |
1.558 |
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| 32958 |
PF3D7_1039100 |
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DnaJ protein, putative, pseudogene? MEC domain-containing protein |
1.544 |
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| 32955 |
PF3D7_1022500 |
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citrate synthase, mitochondrial, putative |
0.743 |
2.3.3.1 |
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| 32960 |
PF3D7_1110700 |
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actin-like protein, putative |
0.742 |
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| 32975 |
PF3D7_1341000 |
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tRNA Arginine |
0.730 |
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| 32977 |
PF3D7_0514400 |
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tRNA Phenylalanine |
0.727 |
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| 32979 |
PF3D7_1370100 |
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tRNA Cysteine |
0.727 |
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| 32982 |
PF3D7_0706800 |
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tRNA Threonine |
0.725 |
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| 32966 |
PF3D7_1357700 |
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U3 small nucleolar RNA-associated protein 21, putative |
0.722 |
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| 32980 |
PF3D7_0714700 |
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tRNA Asparagine |
0.720 |
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| 32981 |
PF3D7_1252000 |
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tRNA Glutamine |
0.717 |
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| 32963 |
PF3D7_1218400 |
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triose or hexose phosphate/phosphate translocator, putative |
0.716 |
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| 32950 |
PF3D7_0705900 |
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ATP synthase subunit C, putative |
0.716 |
3.6.3.14 |
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| 32957 |
PF3D7_1032500 |
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DER1-like protein, putative |
0.710 |
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| 32967 |
PF3D7_1444300 |
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1-acyl-sn-glycerol-3-phosphate acyltransferase, putative |
0.709 |
2.3.1.51 |
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| 32968 |
PF3D7_1456800 |
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V-type H(+)-translocating pyrophosphatase, putative, VP1 |
0.704 |
3.6.1.1 |
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| 32956 |
PF3D7_1025600 |
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COX17 cytochrome c oxidase copper chaperone, putative |
0.699 |
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| 33234 |
PF3D7_0209900 |
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ncRNA |
0.698 |
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| 32948 |
PF3D7_0519200 |
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V-type proton ATPase 16 kDa proteolipid subunit |
0.695 |
3.6.3.14 |
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| 32974 |
PF3D7_0531900 |
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ITS2 |
0.691 |
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| 32972 |
PF3D7_0707000 |
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tRNA Lysine |
0.687 |
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| 32962 |
PF3D7_1215300 |
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10 kDa chaperonin |
0.653 |
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| 32976 |
PF3D7_1370000 |
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tRNA Arginine |
0.651 |
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| 32964 |
PF3D7_1311400 |
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AP-1 complex subunit mu-1 |
0.645 |
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| 32983 |
PF3D7_1370500 |
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ncRNA |
0.632 |
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| 32973 |
PF3D7_0725700 |
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rRNA |
0.622 |
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| 32978 |
PF3D7_0531700 |
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rRNA |
0.598 |
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| 32952 |
PF3D7_0812600 |
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ubiquitin-conjugating enzyme E2, putative |
0.563 |
2.3.2.23 |
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