Methyl Methanesulfonate  - effect of drug on gene transcription
Siwo GH, Smith RS, Tan A, Button-Simons KA, Checkley LA, Ferdig MT. An integrative analysis of small molecule transcriptional responses in the human malaria parasite Plasmodium falciparum. BMC Genomics. 2015 Dec 4;16:1030.PMID: 26637195
Ratio = Transcript of treated vs untreated control
PfID Annotation Ratio EC Transcript
32965 PF3D7_1348800 E1-E2 ATPase, putative 1.827 3.6.3.8
32961 PF3D7_1143200 DnaJ protein, putative 1.769
32954 PF3D7_1022300 ZIP domain-containing protein, putative, ZIPCO 1.763
32951 PF3D7_0718300
cysteine repeat modular protein 2 1.751
32958 PF3D7_1039100 DnaJ protein, putative, pseudogene? MEC domain-containing protein 1.705
32969 PF3D7_1469000
translation initiation factor IF-1 1.701
32971 PF3D7_1477800
acyl-CoA binding protein 1.672
32959 PF3D7_1102200
erythrocyte cytoskeleton-interacting j protein 1.657
32970 PF3D7_1475400 cysteine repeat modular protein 4 1.647
32946 PF3D7_0105300 cyclase-associated protein 1.637
32949 PF3D7_0522500 50S ribosomal protein L17, apicoplast, putative 1.610
32953 PF3D7_0905300
dynein heavy chain, putative 1.584
32947 PF3D7_0220400 DnaJ protein, putative, pseudogene; MEC domain-containing protein 1.558
32958 PF3D7_1039100 DnaJ protein, putative, pseudogene? MEC domain-containing protein 1.544
32955 PF3D7_1022500
citrate synthase, mitochondrial, putative 0.743 2.3.3.1
32960 PF3D7_1110700 actin-like protein, putative 0.742
32975 PF3D7_1341000 tRNA Arginine 0.730
32977 PF3D7_0514400 tRNA Phenylalanine 0.727
32979 PF3D7_1370100 tRNA Cysteine 0.727
32982 PF3D7_0706800 tRNA Threonine 0.725
32966 PF3D7_1357700 U3 small nucleolar RNA-associated protein 21, putative 0.722
32980 PF3D7_0714700 tRNA Asparagine 0.720
32981 PF3D7_1252000 tRNA Glutamine 0.717
32963 PF3D7_1218400 triose or hexose phosphate/phosphate translocator, putative 0.716
32950 PF3D7_0705900
ATP synthase subunit C, putative 0.716 3.6.3.14
32957 PF3D7_1032500 DER1-like protein, putative 0.710
32967 PF3D7_1444300 1-acyl-sn-glycerol-3-phosphate acyltransferase, putative 0.709 2.3.1.51
32968 PF3D7_1456800
V-type H(+)-translocating pyrophosphatase, putative, VP1 0.704 3.6.1.1
32956 PF3D7_1025600
COX17 cytochrome c oxidase copper chaperone, putative 0.699
33234 PF3D7_0209900 ncRNA 0.698
32948 PF3D7_0519200
V-type proton ATPase 16 kDa proteolipid subunit 0.695 3.6.3.14
32974 PF3D7_0531900 ITS2 0.691
32972 PF3D7_0707000 tRNA Lysine 0.687
32962 PF3D7_1215300
10 kDa chaperonin 0.653
32976 PF3D7_1370000 tRNA Arginine 0.651
32964 PF3D7_1311400
AP-1 complex subunit mu-1 0.645
32983 PF3D7_1370500 ncRNA 0.632
32973 PF3D7_0725700 rRNA 0.622
32978 PF3D7_0531700 rRNA 0.598
32952 PF3D7_0812600 ubiquitin-conjugating enzyme E2, putative 0.563 2.3.2.23
Online articles related to Methyl Methanesulfonate - effect of drug on gene transcription retrieved from PubMed