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Protein kinase G-dependent phosphorylation in schizonts |
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Alam MM, Solyakov L, Bottrill AR, Flueck C, Siddiqui FA, Singh S, Mistry S, Viskaduraki M, Lee K, Hopp CS, Chitnis CE, Doerig C, Moon RW, Green JL, Holder, AA, Baker DA, Tobin AB. Phosphoproteomics reveals malaria parasite Protein Kinase G as a signalling hub regulating egress and invasion. Nat Commun. 2015 Jul 7;6:7285. |
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PfID |
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Annotation |
P-site |
EC |
Transcript |
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Invasion/egress-related proteins |
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| 14066 |
PF3D7_0414900 |
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armadillo-domain containing rhoptry protein |
s2346 |
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| 14097 |
PF3D7_1149000 |
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antigen 332, DBL-like protein |
s33, s36 |
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| 14100 |
PF3D7_1251200 |
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coronin |
s570, s571 |
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| 14078 |
PF3D7_0623100 |
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nuclear polyadenylated rna-binding protein nab2 |
s120 |
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| 14107 |
PF3D7_1434500 |
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dynein-related AAA-type ATPase, putative |
s7014 |
3.6.4.2 |
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| 14070 |
PF3D7_0515700 |
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glideosome-associated protein 40, putative |
t433, s436, s445, s446 |
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| 14099 |
PF3D7_1222700 |
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glideosome-associated protein 45 |
s149, s156 |
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| 14065 |
PF3D7_0316700 |
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protein yop1, putative |
s28 |
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| 14072 |
PF3D7_0525800 |
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inner membrane complex protein 1g, putative |
s274, s277 |
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| 14104 |
PF3D7_1342600 |
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myosin A |
s19 |
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| 14075 |
PF3D7_0613900 |
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myosin E, putative |
s1084, s1088 |
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| 14091 |
PF3D7_1021800 |
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schizont egress antigen-1 |
s280 |
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Transporters |
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| 14062 |
PF3D7_0106300 |
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calcium-transporting ATPase, ATP6 |
s482 |
3.6.3.8 |
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| 14068 |
PF3D7_0504000 |
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cation transporting P-ATPase, ATPase3 |
s1028 |
3.6.3.12 |
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| 14101 |
PF3D7_1304200 |
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CorA-like Mg2+ transporter protein, putative, MIT2 |
s72, s75 |
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| 14105 |
PF3D7_1347200 |
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nucleoside transporter 1, NT1 |
s8, s16 |
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| 14086 |
PF3D7_0824400 |
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nucleoside transporter 2, NT2 |
s324, s353, s372 |
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| 27702 |
PF3D7_0614300 |
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major facilitator superfamily-related transporter, MFR1 |
s435, s530 |
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| 14103 |
PF3D7_1340900 |
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sodium-dependent phosphate transporter, PiT |
s361 |
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| 27687 |
PF3D7_0312500 |
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apicomplexan amino acid transporter apiat10 |
s577 |
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| 14094 |
PF3D7_1129900 |
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apicomplexan amino acid transporter apiat4 |
s34 |
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Proteolysis |
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| 14069 |
PF3D7_0506900 |
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rhomboid protease ROM4 |
s92, s94/ s158, s160 |
3.4.21.105 |
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| 23991 |
PF3D7_0907700 |
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proteasome activator 28 |
s92 |
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| 14088 |
PF3D7_0922100 |
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ubiquitin-like protein, putative |
s931 |
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Signalling proteins |
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| 14102 |
PF3D7_1321500 |
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3',5'-cyclic nucleotide phosphodiesterase beta |
s156 |
3.1.4.17 |
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| 14085 |
PF3D7_0802600 |
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Adenylyl cyclase, Acb |
s1572 |
4.6.1.1 |
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| 14063 |
PF3D7_0217500 |
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Calcium-dependent protein kinases; CDPK1 |
s64 |
2.7.11.1 |
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| 14095 |
PF3D7_1138400 |
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guanylyl cyclase alfa Gca |
s674, s4203 |
4.6.1.2 |
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| 23849 |
PF3D7_0709700 |
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monoglyceride lipase |
s14 |
3.1.-.- |
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| 14071 |
PF3D7_0516400 |
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phosducin-like protein 1, putative |
s306, s309, s310 |
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Transcriptional regulation |
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| 15694 |
PF3D7_1006800 |
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G-strand-binding protein 2 |
s92 |
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| 25579 |
PF3D7_1002400 |
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transformer-2 protein homolog beta, putative |
s238 |
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| 23684 |
PF3D7_0730300 |
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AP2 domain transcription factor AP2-L, putative |
s948 |
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| 14096 |
PF3D7_1142500 |
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60S ribosomal protein L28 |
s98 |
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| 25797 |
PF3D7_1360900 |
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RNA-binding protein, putative |
s195 |
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Export proteins |
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| 14067 |
PF3D7_0424600 |
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plasmodium exported protein (phistb) |
t124 |
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| 14084 |
PF3D7_0730900 |
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EMP1-trafficking protein |
s1178/s1274/s1370/s1466/s1562/s1458 |
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Chromatin regulation |
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| 14093 |
PF3D7_1105100 |
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histone H2B |
t14 |
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| 14073 |
PF3D7_0610400 |
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histone H3 |
s29, s33 |
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| 23808 |
PF3D7_0617900 |
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histone H3 variant |
s29, s33, t34 |
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| 14082 |
PF3D7_0711500 |
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regulator of chromosome condensation, putative |
s600, s603, s676 |
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| 14080 |
PF3D7_0624600 |
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iswi chromatin-remodeling complex atpase |
s1898 |
3.6.4.12 |
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| 14098 |
PF3D7_1212900 |
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bromodomain protein 2, putative |
s408 |
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| 15949 |
PF3D7_0611400 |
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swi/snf-related matrix-associated actin-dependent regulator of chromatin |
s104 |
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Other |
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| 14092 |
PF3D7_1027300 |
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peroxiredoxin merozoite capping protein 1 |
s327, s329, t330 |
1.11.1.15 |
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| 14079 |
PF3D7_0624000 |
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hexokinase |
t18 |
2.7.1.1 |
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+23 unchharacterized proteins, |
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6 of which are are proteins that share an association |
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with the motor complex, suggesting that they might function as motor-associated proteins |
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