P. falciparum genes harboring G-quadruplexes
The striking genomic features of P. falciparum, wherein GC richness is uniquely localized in parasite's AT rich genome hint towards existence of regulatory elements in GC rich regions. G-stretches have the potential to form non Watson-Crick secondary structures called G-quadruplexes. Studies in different genomes suggest that DNA or RNA quadruplexes can regulate gene expression.
Bhartiya D, Chawla V, Ghosh S, Shankar R, Kumar N. Genome-wide regulatory dynamics of G-quadruplexes in human malaria parasite Plasmodium falciparum. Genomics. 2016 Oct 24. pii: S0888-7543(16)30094-5.PMID: 27789319.
Functional category PFID New Annotation E.C Transcript
DNA metabolism PF3D7_0318600 cleavage and polyadenylation specificity factor, putative
PF3D7_1425400 DEAD/DEAH box helicase, putative 3.6.4.13
PF3D7_1117800
DNA mismatch repair protein MLH
PF3D7_0726300 DNA mismatch repair protein PMS1, putative
PF3D7_0411900 DNA polymerase alpha 2.7.7.7
PF3D7_0803400 DNA repair and recombination protein RAD54, putative 3.6.4.12
PF3D7_1368800 DNA repair endonuclease XPF, putative 3.1.21.1
PF3D7_0710400 DNA repair protein RAD14, putative 4.2.99.18
PF3D7_1211700 DNA replication licensing factor MCM5, putative
PF3D7_0814200
DNA/RNA-binding protein Alba 1
PF3D7_0614800 endonuclease III homologue, putative 4.2.99.18
PF3D7_1360900 RNA-binding protein, putative
PF3D7_1107300
polyadenylate-binding protein-interacting protein 1, putative
PF3D7_0409600 replication protein A1, large subunit
PF3D7_0623900 ribonuclease H2 subunit A, putative 3.1.26.4
RNA metabolism PF3D7_1243100 zinc finger protein, putative
PF3D7_1031500
ATP-dependent DNA helicase ddx3x 3.6.4.13
PF3D7_0318200 DNA-directed RNA polymerase II subunit RPB1 2.7.7.6
PF3D7_1472700 DNA-directed RNA polymerase, alpha subunit, putative 2.7.7.6
PF3D7_1244000 glucose inhibited division protein a homologue, putative
PF3D7_0611900 lsm12, putative
PF3D7_0822100 mediator of RNA polymerase II transcription subunit 7, putative
PF3D7_1235500 mRNA methyltransferase, putative, METTL14 2.1.1.62
PF3D7_0917600
pre-mRNA-splicing factor ATP-dependent RNA helicase PRP43, putative 3.6.4.13
PF3D7_0515000 pre-mRNA-splicing factor CWC2, putative
PF3D7_0422500 pre-mRNA-splicing helicase BRR2, putative 3.6.4.13
PF3D7_1005500
regulator of nonsense transcripts 1, putative
PF3D7_0509400
RNA polymerase I 2.7.7.6
PF3D7_0319500 RNA-binding protein, putative
PF3D7_0416000 RNA-binding protein, putative
PF3D7_1310700
PhIL1-interacting protein PhIP
PF3D7_1326300 RNA-binding protein, putative
PF3D7_1407100
rRNA 2'-O-methyltransferase fibrillarin, putative
PF3D7_0422900 methyltransferase, putative
PF3D7_0517300
serine/arginine-rich splicing factor 1
PF3D7_1217200 multiple rna-binding domain-containing protein 1
PF3D7_1234800 splicing factor 3B subunit 3, putative
PF3D7_1420000 splicing factor 3B subunit 4, putative
PF3D7_0420300
AP2 domain transcription factor
PF3D7_1239200
transcription factor with AP2 domain(s)
PF3D7_1317200 AP2 domain transcription factor AP2-FG
PF3D7_1342900 ap2 domain transcription factor ap2-hs
PF3D7_1466400
AP2 domain transcription factor AP2-SP/EXP
PF3D7_0623600 splicing factor-like protein, putative
PF3D7_1014600 transcriptional coactivator ADA2
PF3D7_0408900
tRNA N6-adenosine threonylcarbamoyltransferase 2.6.99.4
PF3D7_1105700 tRNA-splicing ligase RTCB 6.5.1.3
PF3D7_1306900 U1 small nuclear ribonucleoprotein A, putative
PF3D7_0935000 U2 small nuclear ribonucleoprotein B'', putative
PF3D7_1448000 U3 small nucleolar RNA-associated protein 12, putative
PF3D7_1309300 U4/U6 small nuclear ribonucleoprotein PRP3, putative
PF3D7_1009400 zinc finger protein, putative
Translation PF3D7_0801100 28S ribosomal RNA
PF3D7_0516200 40S ribosomal protein S11
PF3D7_0317600 40S ribosomal protein S11, putative
PF3D7_1317800 40S ribosomal protein S19
PF3D7_0705700 40S ribosomal protein S29, putative
PF3D7_0918200 50S ribosomal protein L3, apicoplast, putative
PF3D7_1331800 60S ribosomal protein L23, putative
PF3D7_0509600
asparagine--tRNA ligase 6.1.1.22
PF3D7_0514300 aspartate--tRNA ligase, putative 6.1.1.12
PF3D7_1331700
glutamine--tRNA ligase, putative 6.1.1.18
PF3D7_1431300 large subunit GTPase 1, putative 3.6.5.1
PF3D7_1350100
lysine--tRNA ligase 6.1.1.6
PF3D7_1416800
lysine--tRNA ligase, putative 6.1.1.6
PF3D7_0212300 eukaryotic peptide chain release factor subunit 1, putative; ERF1 3.1.1.29
PF3D7_0704900 peptide chain release factor 2 3.1.1.29
PF3D7_0603700
phenylalanine--tRNA ligase 6.1.1.20
PF3D7_1213800
prolyl-tRNA synthetase proline--tRNA ligase 6.1.1.15
PF3D7_0203700 protein MAK16, putative
PF3D7_1346100
protein transport protein SEC61 subunit alpha
PF3D7_1010000 ribosomal protein L43, mitochondrial, putative
PF3D7_1123400 eukaryotic peptide chain release factor GTP-binding subunit, putative, erf3
PF3D7_0828500 translation initiation factor eIF-2B subunit alpha, putative
Post-translational modifications PF3D7_0711000
AAA family ATPase, CDC48 subfamily 3.6.4.6
PF3D7_1230400
ATP-dependent protease subunit ClpQ 3.5.1.98
PF3D7_1414500
atypical protein kinase, ABC-1 family, putative 1.14.13.-
PF3D7_1453700 co-chaperone p23
PF3D7_1302600
deoxyhypusine hydroxylase 1.14.99.29
PF3D7_0911900
inhibitor of cysteine proteases falstatin
PF3D7_0409400
chaperone protein dnaj; heat shock protein 40
PF3D7_1108700
heat shock protein 40, type ii
PF3D7_0628100
hect domain-containing protein 1, putative 6.3.2.19
PF3D7_1028000 methyltransferase, putative 2.1.1.61
PF3D7_0109500 N-acetyltransferase, putative 2.3.1.1
PF3D7_1228300
NIMA related kinase 1 2.7.11.1
PF3D7_0507700 nuclear protein localization protein 4, putative
PF3D7_0205400 PCI domain-containing protein, putative
PF3D7_1349700 peptidase, putative
PF3D7_0322000
peptidyl-prolyl cis-trans isomerase 5.2.1.8
PF3D7_0528700
peptidyl-prolyl cis-trans isomerase 5.2.1.8
PF3D7_1202400
peptidyl-prolyl cis-trans isomerase 5.2.1.8
PF3D7_1313300
peptidyl-prolyl cis-trans isomerase, putative 5.2.1.8
PF3D7_0311700
plasmepsin VI 3.4.23.-
PF3D7_1428300 proliferation-associated protein 2g4, putative
PF3D7_1011400
proteasome subunit beta type-5 3.4.25.1
PF3D7_1426200
protein arginine N-methyltransferase 1 2.1.1.125
PF3D7_0628200
eukaryotic translation initiation factor 2-alpha kinase 2.7.11.1
PF3D7_0311400 kinase-related protein pkrp
PF3D7_0724600 protein kinase, putative 2.7.11.1
PF3D7_0926100 protein kinase, putative 2.7.11.1
PF3D7_0926300 protein kinase, putative 2.7.11.17
PF3D7_1315100
serine/threonine protein kinase PK9 2.7.11.1
PF3D7_1148000
serine/threonine protein kinase, putative 2.7.11.1
PF3D7_1114700
cyclin-dependent-like kinase clk3 2.7.11.1
PF3D7_0802800
serine/threonine protein phosphatase 2B catalytic subunit A 3.1.3.16
PF3D7_1018200 serine/threonine protein phosphatase 8, putative 3.1.3.16
PF3D7_1136900
subtilisin-like protease 2 3.4.21.62
PF3D7_0915100
SUMO-conjugating enzyme UBC9
PF3D7_0516700 ubiquitin carboxyl-terminal hydrolase 2, putative 3.4.19.12
PF3D7_1365400 adenylyltransferase and sulfurtransferase uba4, putative 2.7.7.-
PF3D7_1033900 ubiquitin-conjugating enzyme e2, putative 2.3.2.23
PF3D7_1314800
ubiquitin-like protein, putative
Chromosome structure PF3D7_0603800
NdP2 protein, putative
PF3D7_0509100
structural maintenance of chromosomes protein 4
PF3D7_0813200 CS domain protein, putative
PF3D7_1336800 nuclear movement protein, putative
PF3D7_0711500 regulator of chromosome condensation, putative
PF3D7_0624600
iswi chromatin-remodeling complex atpase 3.6.4.12
PF3D7_0608700 T-complex protein 1 subunit zeta
Histone modifications PF3D7_1234100
bromodomain protein 5
PF3D7_1023900
SNF2 helicase, putative chromodomain-helicase-DNA-binding protein 1 homolog, putative 3.6.4.12
PF3D7_1020700 histone acetyltransferase, putative 2.3.1.1
PF3D7_0416400
histone acetyltransferase, putative 2.3.1.48
PF3D7_0925700
histone deacetylase 1 3.5.1.98
PF3D7_0711400 histone deacetylase complex subunit SAP18, putative
PF3D7_1472200
histone deacetylase, putative 3.5.1.98
PF3D7_0320900
H2A.Z
PF3D7_1105000
histone H4
PF3D7_0403900 SET domain protein, putative 2.1.1.43
Amino acid metabolism PF3D7_0405700
lysine decarboxylase, putative 4.1.1.18
PF3D7_0413700 lysine decarboxylase-like protein, putative 4.1.1.18
PF3D7_1430700
NADP-specific glutamate dehydrogenase 1.4.1.4
PF3D7_1205100 O-phosphoseryl-tRNA(Sec) selenium transferase, putative 2.9.1.2
PF3D7_0522300
S-adenosylmethionine-dependent methyltransferase, putative 2.1.1.12
PF3D7_1236700 S-adenosyl-methyltransferase, putative 2.1.1.12
Carbohydrate metabolism PF3D7_1454700
6-phosphogluconate dehydrogenase, decarboxylating, putative 1.1.1.44
PF3D7_1444800
fructose-bisphosphate aldolase 4.1.2.13
PF3D7_1453800
glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase 1.1.1.49
PF3D7_1436000 glucose-6-phosphate isomerase 5.3.1.9
PF3D7_1462800
glyceraldehyde-3-phosphate dehydrogenase 1.2.1.12
PF3D7_0922500
phosphoglycerate kinase 2.7.2.3
PF3D7_0310300 phosphoglycerate mutase, putative 5.4.2.11
PF3D7_1446400
pyruvate dehydrogenase E1 component subunit beta 1.2.4.1
PF3D7_0626800
pyruvate kinase 2.7.1.40
PF3D7_1037100
pyruvate kinase 2, pyrkii 2.7.1.40
PF3D7_1343600 UDP-N-acetylglucosamine pyrophosphorylase, putative 2.7.7.23
Nucleotide metabolism PF3D7_1308200
carbamoyl phosphate synthetase 6.3.5.5
PF3D7_1138400
guanylyl cyclase alfa Gca 4.6.1.2
PF3D7_0605600
nucleoside diphosphate kinase, putative 2.7.4.6
Lipid metabolism PF3D7_0401900 acyl-CoA synthetase 6.2.1.3
PF3D7_1469600
acetyl-coa carboxylase 6.3.4.14
PF3D7_0322300
diacylglycerol O-acyltransferase 2.3.1.20
PF3D7_0615100
enoyl-acyl carrier reductase 1.3.1.9
PF3D7_0705500
inositol-phosphate phosphatase, putative 3.1.3.25
PF3D7_0714300
palmitoyltransferase, putative 2.3.1.-
PF3D7_1321400
palmitoyltransferase, putative 2.3.1.-
PF3D7_0311300 phosphatidylinositol 3- and 4-kinase, putative 2.7.1.67
PF3D7_0515300
phosphatidylinositol 3-kinase 2.7.1.137
PF3D7_0509800
phosphatidylinositol 4-kinase beta 2.7.1.67
PF3D7_1343000
phosphoethanolamine N-methyltransferase 2.1.1.103
PF3D7_0704400 phosphoinositide-binding protein, putative
PF3D7_1415700
serine palmitoyltransferase, putative 2.3.1.50
Cofactor metabolism PF3D7_1337200
1-deoxy-D-xylulose 5-phosphate synthase 2.2.1.7
PF3D7_1240000 3-hydroxyisobutyryl-CoA hydrolase, putative 4.2.1.17
PF3D7_1142400
coproporphyrinogen-III oxidase HemF 1.3.3.3
PF3D7_1147500
protein farnesyltransferase subunit beta 2.5.1.58
PF3D7_1453500 NAD(P) transhydrogenase, putative, nth 1.6.1.1
Redox metabolsim PF3D7_1353700 reactive oxygen species modulator 1, putative
PF3D7_0814900
superoxide dismutase [Fe] 1.15.1.1
PF3D7_0923800
thioredoxin reductase 1.8.1.9
Intracellular traffic PF3D7_0606700 coatomer alpha subunit, putative
PF3D7_1145100 coatomer subunit gamma, putative
PF3D7_1353600
ER lumen protein retaining receptor
PF3D7_1017300
golgi re-assembly stacking protein 2
PF3D7_0804900 GTPase-activating protein, putative
PF3D7_0907200 GTPase-activating protein, putative
PF3D7_0508500
nd6 protein, putative
PF3D7_1116400
guanine nucleotide-exchange factor SEC12
PF3D7_1230700
protein transport protein SEC13
PF3D7_0214100
protein transport protein SEC31
PF3D7_0724000 Rab GTPase activator and protein kinase, putative
PF3D7_0807300
ras-related protein Rab-18 3.6.5.2
PF3D7_1324700
SNARE protein, putative
PF3D7_1309700 vacuolar protein sorting-associated protein 18, putative
PF3D7_1110500
vacuolar protein sorting-associated protein 35, putative
PF3D7_0103100 vacuolar protein sorting-associated protein 51, putative
Protein export PF3D7_0619400
cell division cycle protein 48 homologue, putative
PF3D7_0718300
cysteine repeat modular protein 2
PF3D7_1033200
early transcribed membrane protein 10.2
PF3D7_0829600 early transcribed membrane protein 8
PF3D7_0302300 erythrocyte membrane protein 1 (PfEMP1), pseudogene
PF3D7_0402800 erythrocyte membrane protein 1 (PfEMP1), pseudogene
PF3D7_1240200 erythrocyte membrane protein 1 (PfEMP1), pseudogene
PF3D7_0600100 erythrocyte membrane protein 1 (PfEMP1), pseudogene
PF3D7_1219400 erythrocyte membrane protein 1 (PfEMP1), pseudogene
PF3D7_1400100 erythrocyte membrane protein 1 (PfEMP1), truncated, pseudogene
PF3D7_0100100
erythrocyte membrane protein 1, PfEMP1
PF3D7_0115700
erythrocyte membrane protein 1, PfEMP1
PF3D7_0200100 erythrocyte membrane protein 1, PfEMP1
PF3D7_0223500
erythrocyte membrane protein 1, PfEMP1
PF3D7_0300100 erythrocyte membrane protein 1, PfEMP1
PF3D7_0324900
erythrocyte membrane protein 1, PfEMP1
PF3D7_0400100 erythrocyte membrane protein 1, PfEMP1
PF3D7_0400400
erythrocyte membrane protein 1, PfEMP1
PF3D7_0412400 erythrocyte membrane protein 1, PfEMP1
PF3D7_0412700
erythrocyte membrane protein 1, PfEMP1
PF3D7_0412900 erythrocyte membrane protein 1, PfEMP1
PF3D7_0413100 erythrocyte membrane protein 1, PfEMP1
PF3D7_0420700 erythrocyte membrane protein 1, PfEMP1
PF3D7_0420900 erythrocyte membrane protein 1, PfEMP1
PF3D7_0421100 erythrocyte membrane protein 1, PfEMP1
PF3D7_0421300
erythrocyte membrane protein 1, PfEMP1
PF3D7_0425800
erythrocyte membrane protein 1, PfEMP1
PF3D7_0426000 erythrocyte membrane protein 1, PfEMP1
PF3D7_0500100 erythrocyte membrane protein 1, PfEMP1
PF3D7_0600200 erythrocyte membrane protein 1, PfEMP1
PF3D7_0617400 erythrocyte membrane protein 1, PfEMP1
PF3D7_0632500
erythrocyte membrane protein 1, PfEMP1
PF3D7_0632800 erythrocyte membrane protein 1, PfEMP1
PF3D7_0700100
erythrocyte membrane protein 1, PfEMP1
PF3D7_0711700
erythrocyte membrane protein 1, PfEMP1
PF3D7_0712000
erythrocyte membrane protein 1, PfEMP1
PF3D7_0712400 erythrocyte membrane protein 1, PfEMP1
PF3D7_0712600 erythrocyte membrane protein 1, PfEMP1
PF3D7_0712800 erythrocyte membrane protein 1, PfEMP1
PF3D7_0712900
erythrocyte membrane protein 1, PfEMP1
PF3D7_0733000 erythrocyte membrane protein 1, PfEMP1
PF3D7_0800100 erythrocyte membrane protein 1, PfEMP1
PF3D7_0800200
erythrocyte membrane protein 1, PfEMP1
PF3D7_0800300
erythrocyte membrane protein 1, PfEMP1
PF3D7_0808600 erythrocyte membrane protein 1, PfEMP1
PF3D7_0808700
erythrocyte membrane protein 1, PfEMP1
PF3D7_0809100 erythrocyte membrane protein 1, PfEMP1
PF3D7_0833500 erythrocyte membrane protein 1, PfEMP1
PF3D7_0900100 erythrocyte membrane protein 1, PfEMP1
PF3D7_0937800 erythrocyte membrane protein 1, PfEMP1
PF3D7_1041300 erythrocyte membrane protein 1, PfEMP1
PF3D7_1100100 erythrocyte membrane protein 1, PfEMP1
PF3D7_1100200
erythrocyte membrane protein 1, PfEMP1
PF3D7_1150400
erythrocyte membrane protein 1, PfEMP1
PF3D7_1200100 erythrocyte membrane protein 1, PfEMP1
PF3D7_1219300 erythrocyte membrane protein 1, PfEMP1
PF3D7_1240300 erythrocyte membrane protein 1, PfEMP1
PF3D7_1240400 erythrocyte membrane protein 1, PfEMP1
PF3D7_1240600
erythrocyte membrane protein 1, PfEMP1
PF3D7_1240900 erythrocyte membrane protein 1, PfEMP1
PF3D7_1255200 erythrocyte membrane protein 1, PfEMP1
PF3D7_1300300 erythrocyte membrane protein 1, PfEMP1
PF3D7_1373500 erythrocyte membrane protein 1, PfEMP1
PF3D7_1200600
erythrocyte membrane protein 1, PfEMP1
PF3D7_0906000
exoribonuclease II 3.1.27.1
PF3D7_0601300 exported protein family 1
PF3D7_0701700 exported protein family 1
PF3D7_1101800
exported protein family 1
PF3D7_0101400
exported protein family 1, pseudogene
PF3D7_0220000 liver stage antigen 3
PF3D7_0114100
Pfmc-2TM Maurer's cleft two transmembrane protein
PF3D7_0222100
Pfmc-2TM Maurer's cleft two transmembrane protein
PF3D7_0324100
Pfmc-2TM Maurer's cleft two transmembrane protein
PF3D7_0631400
Pfmc-2TM Maurer's cleft two transmembrane protein
PF3D7_1039700
Pfmc-2TM Maurer's cleft two transmembrane protein
PF3D7_0532200
Plasmodium exported protein (PHISTc), unknown function
PF3D7_0113200
Plasmodium exported protein, unknown function
PF3D7_0201000 rifin PIR protein
PF3D7_0222600 rifin
PF3D7_0300700 rifin
PF3D7_0400900 rifin
PF3D7_0401000 rifin
PF3D7_0500500 PIR protein rifin
PF3D7_0808900 rifin PIR protein
PF3D7_0900300 PIR protein rifin
PF3D7_0901000
rifin
PF3D7_1101200
rifin
PF3D7_1400300 rifin
PF3D7_1479700 rifin PIR protein
PF3D7_0412600 rifin, pseudogene
PF3D7_0421500 rifin, pseudogene
PF3D7_0711900 rifin, pseudogene
PF3D7_1451800
sortilin
PF3D7_0617600
PIR protein stevor
PF3D7_0832900 stevor PIR protein
PF3D7_0603400
trophozoite exported protein 1
Organellar functions PF3D7_0504400
ATP-dependent helicase, putative 3.6.1.3
PF3D7_0708700 cytochrome c oxidase subunit 4, putative, Cox4
PF3D7_1435000 cytochrome c oxidase assembly protein cox15
mal_mito_2 COX 1 cytochrome c oxidase subunit I 1.9.3.1
PF3D7_1232200
dihydrolipoyl dehydrogenase, mitochondrial 1.8.1.4
PF3D7_1413500
ABC transporter I family member 1 FeS assembly ATPase SufC
PF3D7_0607800 GTP-binding protein, putative
PF3D7_0824300 GTP-binding protein obg2, putative
PF3D7_1217300
GTP-binding protein ENGA
PF3D7_1411600
GTP-binding protein protein obg1
PF3D7_0303200 lipin, putative 3.1.3.4
PF3D7_0616800
malate:quinone oxidoreductase, putative 1.1.5.4
PF3D7_0905200
mitochondrial carrier protein, putative
PF3D7_1368700 mitochondrial carrier protein, putative
PF3D7_1434700 mitochondrial import inner membrane translocase subunit TIM17, putative
PF3D7_0627400 mitochondrial import inner membrane translocase subunit TIM22, putative
PF3D7_0828400 mitochondrial inner membrane protein OXA1, putative
PF3D7_0523100 cytochrome b-c1 complex subunit 2, putative 3.4.24.64
PF3D7_1456600 ribosomal protein L28, mitochondrial, putative
PF3D7_1249800 THO complex subunit 2, putative
PF3D7_0915000
type II NADH:ubiquinone oxidoreductase 1.6.5.3
Transport PF3D7_0629500
amino acid transporter aat1
PF3D7_0415000
ATPase get3, putative, Get3
PF3D7_0828600
folate transporter 1 FT1
PF3D7_0316600
formate-nitrite transporter, FNT
PF3D7_1107900
mechanosensitive ion channel protein
PF3D7_1317900 nucleolar complex protein 4, putative
PF3D7_0916000
major facilitator superfamily domain-containing protein, MFS2
PF3D7_0312500
apicomplexan amino acid transporter apiat10
PF3D7_0627700 transportin
PF3D7_1137400 UVB-resistance protein UVR8 homologue
PF3D7_0806800
v-type proton atpase subunit a, putative 3.6.3.14
PF3D7_1456800
V-type H(+)-translocating pyrophosphatase, putative, VP1 3.6.1.1
PF3D7_0934500 V-type proton ATPase subunit E, putative 3.6.3.14
PF3D7_0408300 zinc finger ran-binding domain-containing protein 2, putative
Invasion and motility PF3D7_0903700
alpha tubulin 1
PF3D7_0503400
actin-depolymerizing factor 1
PF3D7_0422300
alpha tubulin 2, transcript expression profile microgametocyte
PF3D7_0423400
apical asparagine-rich protein AARP
PF3D7_0315200 circumsporozoite- and TRAP-related protein
PF3D7_1023100
dynein heavy chain, putative
PF3D7_0530900
formin 1
PF3D7_1219000
formin 2
PF3D7_0423500
glideosome associated protein with multiple membrane spans 2
PF3D7_0724900 kinesin-20, putative
PF3D7_1370300
membrane associated histidine-rich protein
PF3D7_1036000
merozoite surface protein 11
PF3D7_1035400
merozoite surface protein 3
PF3D7_1035500
merozoite surface protein 6
PF3D7_1246400
myosin a-tail interacting protein
PF3D7_1329100
myosin F
PF3D7_0613900 myosin E, putative
PF3D7_0207700
serine repeat antigen 4 3.4.22.-
PF3D7_0902800
serine repeat antigen 9 3.4.22.2
PF3D7_0909500
subpellicular microtubule protein 1, putative
PF3D7_1008700
tubulin beta chain
PF3D7_1475700
tubulin epsilon chain, putative
Unknown function PF3D7_1207700 41-3 protein
PF3D7_0806300 ferlin-like protein, putative
PF3D7_1455600
ferlin, putative
PF3D7_1344100 tbc domain-containing protein, putative
PF3D7_0309300 N2227-like protein, putative
PF3D7_0932100 protein MAM3, putative
PF3D7_1218800 secreted ookinete protein, putative
PF3D7_0518600 WD repeat-containing protein 26, putative
PF3D7_1033500 WD repeat-containing protein 70, putative
PF3D7_1121400 WD repeat-containing protein, putative
PF3D7_1228800 WD repeat-containing protein, putative
PF3D7_1459200 WD repeat-containing protein, putative
+ 89 conserved plasmodium proteins, unknown function + 9 conserved Plasmodium membrane protein, unknown function
Online articles related to P. falciparum genes harboring G-quadruplexes retrieved from PubMed

RX Drugs affecting pathway with unknown specific target

Drug Name PubMed Articles (year of publication)
2,9-bis[(substituted-aminomethyl)phenyl]-1,10-phenanthroline
Quarfloxin