|
Phosphatome - Phosphatases of Plasmodium falciparum |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Combined results of Wilkes JM, Doerig C.The protein-phosphatome of the human malaria parasite Plasmodium falciparum.BMC Genomics. 2008 15;9:412 and Pandey R, Mohmmed A, Pierrot C, Khalife J, Malhotra P, Gupta D. Genome wide in silico analysis of Plasmodium falciparum phosphatome. BMC Genomics. 2014 15:1024. PMID: 25425018 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Ppase domain |
PfID |
|
|
Annotation |
Transcript |
EC |
Sub_cell localization |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
CYTH_like_Pase (Triphosphate Tunnel Metaloenzyme Phosphatases) superfamily |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
14502 |
|
PF3D7_0322100 |
|
|
mRNA-capping enzyme subunit beta |
|
3.1.3.33 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
EEP Exonuclease-endonuclease Phosphatases superfamily |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
14563 |
|
PF3D7_0107200 |
|
|
ccr4 domain-containing protein 3, putative |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
14497 |
|
PF3D7_0305600 |
|
|
AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative |
|
4.2.99.18 |
MIT,AP |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
14501 |
|
PF3D7_0319200 |
|
|
ccr4 domain-containing protein 4, putative |
|
|
AP |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
20717 |
|
PF3D7_1238600 |
|
|
sphingomyelin phosphodiesterase |
|
3.1.4.12 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
14549 |
|
PF3D7_1363500 |
|
|
CCR4 domain-containing protein 2, putative |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
34020 |
|
PF3D7_1430600 |
|
|
endonuclease/exonuclease/phosphatase family protein, putative |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
14509 |
|
PF3D7_0705500 |
|
|
inositol-phosphate phosphatase, putative |
|
3.1.3.25 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
14525 |
|
PF3D7_1111600 |
|
|
endonuclease/exonuclease/phosphatase family protein, putative |
|
3.1.3.56 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
HAD (haloacid dehalogenase) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
14523 |
|
PF3D7_1012700 |
|
|
NLI interacting factor-like phosphatase, putative |
|
3.1.3.16 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
14527 |
|
PF3D7_1118400 |
|
|
haloacid dehalogenase-like hydrolase, putative |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
14546 |
|
PF3D7_1355700 |
|
|
NLI interacting factor-like phosphatase, putative |
|
3.1.3.16 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
14496 |
|
PF3D7_0303200 |
|
|
lipin, putative |
|
3.1.3.4 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
14548 |
|
PF3D7_1363200 |
|
|
bifunctional polynucleotide phosphatase/kinase |
|
3.1.3.32 |
MIT |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
HAD_like (Haloacid Dehalogenase) superfamily |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
14505 |
|
PF3D7_0515900 |
|
|
NLI interacting factor-like phosphatase, putative |
|
|
MIT |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
14510 |
|
PF3D7_0715000 |
|
|
4-nitrophenylphosphatase |
|
3.1.3.41 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
14511 |
|
PF3D7_0726900 |
|
|
mitochondrial import inner membrane translocase subunit TIM50, putative |
|
|
MIT |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
14517 |
|
PF3D7_0817400 |
|
|
phosphatase, putative |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
14535 |
|
PF3D7_1226100 |
|
|
haloacid dehalogenase-like hydrolase, putative |
|
3.1.3.1 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
HP (Histidine phosphatases) superfamily |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
14495 |
|
PF3D7_0208400 |
|
|
conserved Plasmodium protein, unknown function |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
14499 |
|
PF3D7_0310300 |
|
|
phosphoglycerate mutase, putative |
|
5.4.2.11 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
14504 |
|
PF3D7_0413500 |
|
|
phosphoglucomutase-2 |
|
5.4.2.2 |
MIT |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
14528 |
|
PF3D7_1120100 |
|
|
phosphoglycerate mutase, putative |
|
5.4.2.11 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
14554 |
|
PF3D7_1430300 |
|
|
acid phosphatase, putative |
|
3.1.3.2 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
MPP (Metallophosphatase) superfamily |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
14500 |
|
PF3D7_0314400 |
|
|
serine/threonine protein phosphatase 6, putative |
|
3.1.3.16 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
14513 |
|
PF3D7_0802800 |
|
|
serine/threonine protein phosphatase 2B catalytic subunit A |
|
3.1.3.16 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
14518 |
|
PF3D7_0912400 |
|
|
alkaline phosphatase, putative |
|
3.1.3.1 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
14519 |
|
PF3D7_0918000 |
|
|
glideosome-associated protein 50 secreted acid phosphatase |
|
3.1.3.2 |
AP |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
14520 |
|
PF3D7_0925400 |
|
|
protein phosphatase-beta |
|
3.1.3.16 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
14521 |
|
PF3D7_0927700 |
|
|
serine/threonine protein phosphatase 4, putative |
|
3.1.3.16 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
14524 |
|
PF3D7_1018200 |
|
|
serine/threonine protein phosphatase 8, putative |
|
3.1.3.16 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
14532 |
|
PF3D7_1206000 |
|
|
shewanella-like protein phosphatase 2 |
|
3.1.3.16 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
14543 |
|
PF3D7_1340600 |
|
|
RNA lariat debranching enzyme, putative |
|
3.1.4.- |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
14550 |
|
PF3D7_1403900 |
|
|
serine/threonine protein phosphatase cpped1 |
|
3.1.3.2 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
14551 |
|
PF3D7_1406700 |
|
|
vacuolar protein sorting-associated protein 29 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
14552 |
|
PF3D7_1414400 |
|
|
serine/threonine protein phosphatase PP1 |
|
3.1.3.16 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
14559 |
|
PF3D7_1464600 |
|
|
serine/threonine protein phosphatase uis2, putative |
|
3.1.3.16 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
14561 |
|
PF3D7_1469200 |
|
|
shewanella-like protein phosphatase 1, putative |
|
3.1.3.16 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
14553 |
|
PF3D7_1423300 |
|
|
serine/threonine protein phosphatase 7 |
|
3.1.3.16 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
14560 |
|
PF3D7_1466100 |
|
|
protein phosphatase containing kelch-like domains |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
14545 |
|
PF3D7_1355500 |
|
|
serine/threonine protein phosphatase 5 |
|
3.1.3.16 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
14494 |
|
PF3D7_0107800 |
|
|
double-strand break repair protein MRE11 |
|
3.1.11.- |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
14545 |
|
PF3D7_1355500 |
|
|
serine/threonine protein phosphatase 5 |
|
3.1.3.16 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
NBD Nucleoside phosphatase |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
25682 |
|
PF3D7_1322000 |
|
|
nucleoside-diphosphatase, putative |
|
3.6.1.6 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
25940 |
|
PF3D7_1431800 |
|
|
apyrase |
|
3.6.1.5 |
AP |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
PAP2_like (2-phosphatidic acid phosphatases) superfamily |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
14508 |
|
PF3D7_0625000 |
|
|
sphingomyelin synthase 1, putative |
|
2.7.8.27 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
14514 |
|
PF3D7_0805600 |
|
|
phosphatidic acid phosphatase 2; phospholipid phosphatase pap2 |
|
3.1.3.4 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
14547 |
|
PF3D7_1356400 |
|
|
phosphatase 2A regulatory subunit-related protein, putative |
|
3.1.3.16 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
PP2Cc (Protein phosphatases 2c domain) superfamily |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
14503 |
|
PF3D7_0410300 |
|
|
protein phosphatase PPM1, putative |
|
3.1.3.16 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
14506 |
|
PF3D7_1138500 |
|
|
protein phosphatase 2C protein phosphatase PPM2 |
|
3.1.3.16 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
14515 |
|
PF3D7_1455000 |
|
|
protein phosphatase PPM3, putative |
|
3.1.3.16 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
14516 |
|
PF3D7_1249300 |
|
|
protein phosphatase PPM4, putative |
|
3.1.3.16 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
27600 |
|
PF3D7_0810300 |
|
|
protein phosphatase PPM5, putative |
|
3.1.3.16 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
14530 |
|
PF3D7_1309200 |
|
|
protein phosphatase PPM6, putative |
|
3.1.3.16 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
14531 |
|
PF3D7_0810500 |
|
|
protein phosphatase PPM7, putative |
|
3.1.3.16 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
27602 |
|
PF3D7_1135100 |
|
|
protein phosphatase PPM8, putative |
|
3.1.3.16 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
14537 |
|
PF3D7_0520100 |
|
|
protein phosphatase PPM9, putative |
|
3.1.3.16 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
14539 |
|
PF3D7_1009600 |
|
|
protein phosphatase ppm10, putative |
|
3.1.3.16 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
14557 |
|
PF3D7_1208900 |
|
|
protein phosphatase ppm11, putative |
|
3.1.3.16 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
14540 |
|
PF3D7_1319700 |
|
|
protein phosphatase PP2A regulatory subunit A, putative |
|
3.1.3.16 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
PTH2_family (Peptidyl-tRNA hydrolase, type 2) superfamily |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
14507 |
|
PF3D7_0610500 |
|
|
peptidyl-tRNA hydrolase PTRHD1, putative |
|
3.1.1.29 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
PTPc (Protein Tyrosine phosphatase) superfamily |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
14498 |
|
PF3D7_0309000 |
|
|
dual specificity protein phosphatase |
|
3.1.3.16 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
14526 |
|
PF3D7_1113100 |
|
|
protein tyrosine phosphatase |
|
3.1.3.48 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
14529 |
|
PF3D7_1127000 |
|
|
protein phosphatase, putative |
|
3.1.3.16 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
14558 |
|
PF3D7_1455100 |
|
|
protein tyrosine phosphatase, putative |
|
3.1.3.48 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
PTPLA (Protein tyrosine phosphatase-like protein) superfamily |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
14542 |
|
PF3D7_1331600 |
|
|
3-hydroxyacyl-coa dehydratase deh |
|
3.1.3.48 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
RHOD (Rhodanese Homology Domain) superfamily |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
14533 |
|
PF3D7_1206400 |
|
|
thiosulfate sulfurtransferase, putative |
|
2.8.1.1 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
14538 |
|
PF3D7_1305500 |
|
|
mitogen-activated protein kinase phosphatase 1, putative |
|
2.7.11.24 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Syja_N (SacL homology domain) superfamily |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
14512 |
|
PF3D7_0802500 |
|
|
inositol 5-phosphatase, putative |
|
3.1.3.36 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
27580 |
|
PF3D7_1354200 |
|
|
phosphoinositide phosphatase sac1 |
|
3.1.3.56 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|