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Top ranked surface exposed proteins |
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El-Manzalawy Y, Munoz EE, Lindner SE, Honavar V. PlasmoSEP: Predicting surface exposed proteins on the malaria parasite using semi-supervised Self-training and expert-annotated data. Proteomics. 2016 Oct 7. PMID: 27714937. |
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Functional group |
PfID |
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Annotation |
EC# |
Transcript |
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22894 |
DNA metabolism |
PF3D7_1239500 |
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DNA gyrase subunit B |
5.99.1.3 |
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22867 |
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PF3D7_1011700 |
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DNA repair protein RAD23, putative |
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22798 |
RNA metabolism |
PF3D7_0110400 |
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DNA-directed RNA polymerase II subunit RPB9, putative |
2.7.7.6 |
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22875 |
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PF3D7_1108000 |
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IWS1-like protein, putative |
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25653 |
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PF3D7_0602200 |
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MYND-type zinc finger protein, putative |
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22913 |
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PF3D7_1409800 |
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CUGBP Elav-like family member 2 |
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22841 |
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PF3D7_0714500 |
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transcription elongation factor s-II, putative |
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23740 |
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PF3D7_1107800 |
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AP2 domain transcription factor, putative |
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22928 |
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PF3D7_1428800 |
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transcription initiation TFIID-like, putative |
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22883 |
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PF3D7_1120500 |
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tRNA nucleotidyltransferase, putative |
2.7.7.72 |
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22825 |
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PF3D7_0516300 |
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tRNA pseudouridine synthase, putative |
4.2.1.70 |
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22804 |
Translation |
PF3D7_0307100 |
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40S ribosomal protein S12, putative |
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22824 |
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PF3D7_0516200 |
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40S ribosomal protein S11 |
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22806 |
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PF3D7_0309600 |
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60S acidic ribosomal protein P2 |
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22905 |
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PF3D7_1331800 |
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60S ribosomal protein L23, putative |
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22911 |
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PF3D7_1358500 |
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zinc finger protein, putative |
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33924 |
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PF3D7_1244800 |
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translation machinery-associated protein 46, putative |
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25647 |
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PF3D7_0319600 |
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elongation factor 1-delta, putative |
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22803 |
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PF3D7_0305000 |
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elongation factor Ts |
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22836 |
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PF3D7_0621800 |
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nascent polypeptide-associated complex subunit alpha, putative |
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22853 |
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PF3D7_0907900 |
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peptide deformylase |
3.5.1.88 |
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22879 |
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PF3D7_1115600 |
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peptidyl-prolyl cis-trans isomerase |
5.2.1.8 |
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22833 |
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PF3D7_0607000 |
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translation initiation factor IF-2, putative |
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22843 |
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PF3D7_0813600 |
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translation initiation factor SUI1, putative |
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22906 |
Post-translational modifications |
PF3D7_1333000 |
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20 kDa chaperonin |
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30540 |
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PF3D7_0627500 |
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protein DJ-1 |
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22892 |
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PF3D7_1232100 |
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60 kDa chaperonin |
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22923 |
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PF3D7_1454400 |
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aminopeptidase P |
3.4.11.9 |
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22805 |
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PF3D7_0307400 |
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ATP-dependent Clp protease proteolytic subunit |
3.4.21.92 |
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22917 |
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PF3D7_1436800 |
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ATP-dependent Clp protease proteolytic subunit |
3.4.21.92 |
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22907 |
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PF3D7_1342400 |
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casein kinase II beta chain |
2.7.11.1 |
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22881 |
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PF3D7_1116700 |
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dipeptidyl aminopeptidase 1 cathepsin C, homolog |
3.4.14.1 |
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29746 |
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PF3D7_0314000 |
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hsp20-like chaperone, putative |
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22922 |
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PF3D7_1453700 |
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co-chaperone p23 |
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22856 |
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PF3D7_0911900 |
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inhibitor of cysteine proteases falstatin |
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23437 |
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PF3D7_1247400 |
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peptidyl-prolyl cis-trans isomerase fkbp |
5.2.1.8 |
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22882 |
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PF3D7_1116800 |
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heat shock protein 101 chaperone protein ClpB2 |
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22908 |
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PF3D7_1344200 |
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PfHsp70-y |
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22868 |
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PF3D7_1015600 |
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heat shock protein 60 |
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22845 |
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PF3D7_0818900 |
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PfHsp70-1 |
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22857 |
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PF3D7_0917900 |
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PfHsp70-2 |
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22840 |
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PF3D7_0708400 |
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heat shock protein 90 |
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22880 |
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PF3D7_1116300 |
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peptidyl-prolyl cis-trans isomerase |
5.2.1.8 |
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22887 |
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PF3D7_1141800 |
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EELM2 domain-containing protein, putative |
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22916 |
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PF3D7_1416900 |
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prefoldin subunit 2, putative |
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22842 |
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PF3D7_0727400 |
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proteasome subunit alpha type-5, putative |
3.4.25.1 |
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22926 |
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PF3D7_1472600 |
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protein disulfide-isomerase |
5.3.4.1 |
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22848 |
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PF3D7_0827900 |
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protein disulfide isomerase |
5.3.4.1 |
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22847 |
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PF3D7_0826700 |
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receptor for activated c kinase |
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22844 |
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PF3D7_0816500 |
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small heat shock protein HSP20, putative |
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22918 |
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PF3D7_1440200 |
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stromal-processing peptidase, putative |
3.4.24.56 |
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22810 |
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PF3D7_0320300 |
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T-complex protein 1 subunit epsilon |
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22895 |
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PF3D7_1241900 |
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tetratricopeptide repeat protein, putative |
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22851 |
Histone modifications |
PF3D7_0904700 |
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bacterial histone-like protein |
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22891 |
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PF3D7_1224500 |
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histone chaperone ASF1 |
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22811 |
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PF3D7_0320900 |
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H2A.Z |
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22839 |
Chromosome structure |
PF3D7_0702900 |
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centrin, putative |
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22890 |
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PF3D7_1213500 |
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integral membrane protein GPR180, putative |
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25836 |
Amino acid metabolism |
PF3D7_1357900 |
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pyrroline-5-carboxylate reductase, putative |
1.5.1.2 |
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22861 |
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PF3D7_0922200 |
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S-adenosylmethionine synthetase |
2.5.1.6 |
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22869 |
Carbohydrate metabolism |
PF3D7_1015900 |
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enolase |
4.2.1.11 |
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22920 |
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PF3D7_1444800 |
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fructose-bisphosphate aldolase |
4.1.2.13 |
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22854 |
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PF3D7_0909200 |
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GDP-fucose protein O-fucosyltransferase 2, putative |
2.4.1.221 |
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22924 |
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PF3D7_1462800 |
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glyceraldehyde-3-phosphate dehydrogenase |
1.2.1.12 |
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22878 |
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PF3D7_1114800 |
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glycerol-3-phosphate dehydrogenase, putative |
1.1.1.8 |
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29738 |
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PF3D7_0604700 |
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glyoxalase I-like protein gilp |
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22837 |
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PF3D7_0624000 |
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hexokinase |
2.7.1.1 |
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22862 |
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PF3D7_0922500 |
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phosphoglycerate kinase |
2.7.2.3 |
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22800 |
Lipid metabolism |
PF3D7_0208500 |
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acyl carrier protein |
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22902 |
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PF3D7_1323000 |
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beta-hydroxyacyl-ACP dehydratase |
4.2.1.59 |
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29765 |
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PF3D7_1469600 |
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acetyl-coa carboxylase |
6.3.4.14 |
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22866 |
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PF3D7_1010700 |
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dolichyl-phosphate-mannose-protein mannosyltransferase, putative |
2.4.1.109 |
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22860 |
Nucleotide metabolism |
PF3D7_0920800 |
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inosine-5'-monophosphate dehydrogenase |
1.1.1.205 |
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22823 |
|
PF3D7_0513300 |
|
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purine nucleoside phosphorylase |
2.4.2.1 |
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22827 |
Cofactor synthesis |
PF3D7_0520500 |
|
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phosphomethylpyrimidine kinase, putative |
2.7.1.49 |
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22901 |
Protein trafic |
PF3D7_1314500 |
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transmembrane emp24 domain-containing protein, putative |
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22877 |
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PF3D7_1108600 |
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endoplasmic reticulum-resident calcium binding protein |
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22807 |
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PF3D7_0310400 |
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TVN-junction protein 1 parasite-infected erythrocyte surface protein |
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22846 |
|
PF3D7_0822600 |
 |
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protein transport protein SEC23 |
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22822 |
|
PF3D7_0509000 |
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|
alpha-soluble nsf attachment protein, putative |
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34041 |
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PF3D7_1441800 |
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vacuolar protein sorting-associated protein 60, putative |
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22830 |
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PF3D7_0526900 |
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transmembrane emp24 domain-containing protein, putative |
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22816 |
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PF3D7_0422100 |
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transmembrane emp24 domain-containing protein, putative |
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23623 |
Protein export |
PF3D7_1147800 |
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membrane associated erythrocyte binding-like protein |
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22884 |
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PF3D7_1129100 |
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parasitophorous vacuolar protein 1 |
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22814 |
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PF3D7_0406200 |
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parasitophorous vacuole membrane protein s16; sexual stage-specific protein s16 |
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22893 |
Organellar functions |
PF3D7_1235700 |
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ATP synthase subunit beta, mitochondrial |
3.6.3.14 |
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22871 |
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PF3D7_1025600 |
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COX17 cytochrome c oxidase copper chaperone, putative |
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22872 |
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PF3D7_1034400 |
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flavoprotein subunit of succinate dehydrogenase |
1.3.5.1 |
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22915 |
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PF3D7_1411400 |
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plastid replication-repair enzyme |
2.7.7.7 |
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22876 |
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PF3D7_1108500 |
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succinate--CoA ligase [ADP-forming] subunit alpha, putative |
6.2.1.4 |
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22821 |
Invasion and motility |
PF3D7_0508000 |
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6-cysteine protein |
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22812 |
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PF3D7_0404900 |
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6-cysteine protein |
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22897 |
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PF3D7_1246200 |
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actin I |
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22850 |
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PF3D7_0903700 |
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alpha tubulin 1 |
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22817 |
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PF3D7_0422300 |
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alpha tubulin 2, transcript expression profile microgametocyte |
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22886 |
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PF3D7_1133400 |
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apical membrane antigen 1 |
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22813 |
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PF3D7_0405900 |
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apical sushi protein |
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22802 |
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PF3D7_0302200 |
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cytoadherence linked asexual protein 3.2 |
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22904 |
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PF3D7_1323700 |
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glideosome associated protein with multiple membrane spans 1 |
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22912 |
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PF3D7_1406800 |
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glideosome associated protein with multiple membrane spans 3 |
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22849 |
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PF3D7_0828800 |
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GPI-anchored micronemal antigen |
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22863 |
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PF3D7_0929400 |
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high molecular weight rhoptry protein 2 |
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22852 |
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PF3D7_0905400 |
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high molecular weight rhoptry protein 3 |
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22829 |
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PF3D7_0525800 |
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inner membrane complex protein 1g, putative |
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22864 |
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PF3D7_0930300 |
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merozoite surface protein 1 |
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22815 |
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PF3D7_0408700 |
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perforin-like protein 1 |
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22820 |
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PF3D7_0506900 |
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rhomboid protease ROM4 |
3.4.21.105 |
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22921 |
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PF3D7_1452000 |
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rhoptry neck protein 2 |
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22899 |
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PF3D7_1252100 |
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rhoptry neck protein 3 |
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22801 |
|
PF3D7_0214900 |
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