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SNAREs and their accessories |
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Protein name |
PfID |
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Annotation |
Comments |
SNARE type |
EC# |
Transcript |
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35579 |
Ykt6.1 |
PF3D7_0910600 |
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SNARE protein |
V-SNARE Synaptobrevin; Longin |
v-SNARE |
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35590 |
Ykt6.2 |
PF3D7_1324700 |
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SNARE protein, putative |
longin; Synaptobrevin |
v-SNARE |
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35585 |
Syn2 |
PF3D7_1210100 |
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syntaxin, Qa-SNARE family |
Target SNARE coiled-coil region; Qa-SNARE family |
t-SNARE |
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35597 |
Syn3 |
PF3D7_1456200 |
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conserved Plasmodium protein, unknown function |
Target SNARE coiled-coil region |
t-SNARE |
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35592 |
Syn5 |
PF3D7_1332000 |
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syntaxin, Qa-SNARE family |
Target SNARE coiled-coil region |
t-SNARE |
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35575 |
Syn6 |
PF3D7_0530100 |
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SNARE protein, putative |
Target SNARE coiled-coil region |
t-SNARE |
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35593 |
Syn11 |
PF3D7_1432000 |
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syntaxin, Qa-SNARE family |
Target SNARE coiled-coil region |
t-SNARE |
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35583 |
Syn13 |
PF3D7_1104100 |
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syntaxin, Qa-SNARE family |
Target SNARE coiled-coil region |
t-SNARE |
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35586 |
Syn16 |
PF3D7_1243000 |
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syntaxin-16, putative |
Target SNARE coiled-coil region; Syntaxin/epimorphin coiled-coil |
t-SNARE |
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35570 |
Syn17 |
PF3D7_0210700 |
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syntaxin, Qa-SNARE family |
Target SNARE coiled-coil region |
t-SNARE |
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35591 |
Syn18 |
PF3D7_1326800 |
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syntaxin, Qa-SNARE family |
Target SNARE coiled-coil region matches |
t-SNARE |
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35595 |
Vti1 |
PF3D7_1448600 |
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SNARE protein, putative |
Target SNARE coiled-coil region |
t-SNARE |
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35581 |
Bet1 |
PF3D7_1011200 |
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bet1-like protein, putative |
Target SNARE coiled-coil region |
t-SNARE |
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35596 |
Bet1 |
PF3D7_1452500 |
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syntaxin-6, putative |
SNARE domain-containing protein; Syntaxin 6 |
t-SNARE |
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35588 |
SEC20 |
PF3D7_1316800 |
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protein transport protein SEC20, putative |
forms a complex with syntaxin, SEC22 and USE1; involved in the transport from cis-Golgi to ER |
? |
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35573 |
Sec22 |
PF3D7_0320100 |
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protein transport protein SEC22 |
Synaptobrevin; Longin; R-SNARE |
v-SNARE |
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35587 |
VAMP8 |
PF3D7_1303200 |
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SNARE protein, putative |
Synaptobrevin; Longin; R-SNARE |
v-SNARE |
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35578 |
VAMP7 |
PF3D7_0826600 |
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SNARE protein, putative |
Synaptobrevin |
v-SNARE |
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35589 |
SNAP23 |
PF3D7_1320500 |
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SNARE protein, putative |
Target SNARE coiled-coil region |
t-SNARE |
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35574 |
SNAP |
PF3D7_0509000 |
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alpha-soluble nsf attachment protein, putative |
Soluble NSF attachment protein |
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35584 |
GS27 |
PF3D7_1111300 |
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protein transport protein BOS1, putative |
SNARE region anchored in the vesicle membrane C-terminus |
v-SNARE |
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35572 |
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PF3D7_0314100 |
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vesicle transport v-SNARE protein, putative |
V-SNARE_C |
v-SNARE |
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35594 |
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PF3D7_0710800 |
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protein transport protein USE1, putative |
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v-SNARE |
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35576 |
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PF3D7_1439800 |
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vesicle-associated membrane protein, putative |
VAMP-associated protein |
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35582 |
Sec1 |
PF3D7_0613700 |
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syntaxin binding protein, putative |
Sec1 |
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35580 |
Sec1 |
PF3D7_1034000 |
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Sec1 family protein, putative, SLY1 |
Sec1 |
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35571 |
VPS33 |
PF3D7_0935200 |
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vacuolar protein sorting-associated protein 33, putative |
Sec1/munc18-like |
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35577 |
VPS45 |
PF3D7_0216400 |
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vacuolar protein sorting-associated protein 45, putative |
Sec1/munc18-like |
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Rab1A |
PF3D7_0513800 |
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ras-related protein Rab-1A |
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3.6.5.2 |
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Rab1B |
PF3D7_0512600 |
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ras-related protein Rab-1B |
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3.6.5.2 |
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Rab2 |
PF3D7_1231100 |
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ras-related protein Rab-2 |
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3.6.5.2 |
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Rab5A |
PF3D7_0211200 |
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ras-related protein Rab-5A |
Intracellular granula; involved in hemoglobin uptake |
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3.6.5.2 |
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Rab5B |
PF3D7_1310600 |
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ras-related protein Rab-5B secretory complex protein 61 alpha |
PPM, FV, ER, tubovesicular network; interacts with casein kinase-1 |
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3.6.5.2 |
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Rab5C |
PF3D7_0106800 |
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ras-related protein Rab-5C |
Intracellular granula |
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3.6.5.2 |
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Rab6 |
PF3D7_1144900 |
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ras-related protein Rab-6 |
Golgi/ER |
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3.6.5.2 |
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Rab7 |
PF3D7_0903200 |
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ras-related protein RAB7 |
Endosomes ; interacts with PKA-C |
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3.6.5.2 |
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Rab11A |
PF3D7_1320600 |
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ras-related protein Rab-11A |
Vesicular intracellular structures in TZ and GC; rhoptries in SZ |
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3.6.5.2 |
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Rab11B |
PF3D7_1340700 |
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ras-related protein Rab-11B |
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3.6.5.2 |
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Rab18 |
PF3D7_0807300 |
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ras-related protein Rab-18 |
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3.6.5.2 |
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VPS9 (putative GEF) |
PF3D7_0815800 |
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vacuolar protein sorting-associated protein 9, putative |
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VPS10 (Sortilin) |
PF3D7_1451800 |
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sortilin |
Golgi; involved in merozoite formation and apical complex biogenesis |
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VPS45 |
PF3D7_0216400 |
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vacuolar protein sorting-associated protein 45, putative |
Involved in endosome-mediated hemoglobin uptake and IMC biogenesis |
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(S/M protein) |
PF3D7_0502000 |
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vacuolar protein sorting-associated protein 11, putative |
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VPS26 |
PF3D7_1250300 |
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vacuolar protein sorting-associated protein 26, putative |
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VPS29 |
PF3D7_1406700 |
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vacuolar protein sorting-associated protein 29 |
Endosomes |
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VPS35 |
PF3D7_1110500 |
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vacuolar protein sorting-associated protein 35, putative |
Endosomes |
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VPS51 |
PF3D7_0103100 |
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vacuolar protein sorting-associated protein 51, putative |
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VPS52 |
PF3D7_1323800 |
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vacuolar protein sorting-associated protein 52, putative |
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VPS53 |
PF3D7_0727000 |
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vacuolar protein sorting-associated protein 53, putative |
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VPS11 |
PF3D7_0502000 |
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vacuolar protein sorting-associated protein 11, putative |
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VPS16 |
PF3D7_1239900 |
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vacuolar protein sorting-associated protein 16, putative |
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VPS18 |
PF3D7_1309700 |
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vacuolar protein sorting-associated protein 18, putative |
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VPS3 |
PF3D7_1423800 |
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vacuolar protein sorting-associated protein 3, putative |
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VPS15 |
PF3D7_0823000 |
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serine/threonine protein kinase vps15 |
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VPS34 (PI3K) |
PF3D7_0515300 |
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phosphatidylinositol 3-kinase |
Involved in hemoglobin trafficking [71] |
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2.7.1.137 |
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VPS2 |
PF3D7_0816200 |
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vacuolar protein sorting-associated protein 2, putative |
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VPS32 (SNF7) |
PF3D7_1243500 |
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vacuolar protein-sorting-associated protein 32, putative |
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VPS46 |
PF3D7_0906100 |
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vacuolar protein sorting-associated protein 46, putative |
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VPS60 |
PF3D7_1441800 |
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vacuolar protein sorting-associated protein 60, putative |
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VPS4 |
PF3D7_1457500 |
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vacuolar protein sorting-associated protein 4 |
Mediates multivesicular body formation |
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SLY1 |
PF3D7_1034000 |
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Sec1 family protein, putative, SLY1 |
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S/M protein |
PF3D7_0613700 |
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syntaxin binding protein, putative |
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NSF |
PF3D7_0303000 |
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N-ethylmaleimide-sensitive fusion protein |
FV, vesicular structures; exhibits ATPase activity |
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3.6.4.6 |
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α-SNAP |
PF3D7_0509000 |
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alpha-soluble nsf attachment protein, putative |
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FLP |
PF3D7_0806300 |
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ferlin-like protein, putative |
Involved in gamete egress |
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VAMP |
PF3D7_1439800 |
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vesicle-associated membrane protein, putative |
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