Malaria Parasite Metabolic Pathways
Drugs affecting pathway with unknown specific target
| Drug Name | PubMed Articles (year of publication) |
|---|---|
| Artemisinin | |
| Biochemical analyses, suggested target |
Post-translational modification –SUMOylation map details
| PFID | PFID Old | Annotation | Formal Annotation | EC | Transcript |
|---|---|---|---|---|---|
| PF3D7_1144500 | PF11_0457 | Aos1 | SUMO-activating enzyme subunit 1 |
|
|
| PF3D7_1360700 | MAL13P1.302 | E3 SUMO-protein ligase PIAS, putative | E3 SUMO-protein ligase PIAS, putative | 2.3.2.27 |
|
PF3D7_0505800
|
PFE0285c | SUMO | small ubiquitin-related modifier |
|
|
PF3D7_1237000
|
PFL1790w | Uba2 | SUMO-activating enzyme subunit 2 | 6.2.1.45 |
|
|
PF3D7_0915100
|
PFI0740c | Ubc9 | SUMO-conjugating enzyme UBC9 | 6.3.2.19 |
|
| PF3D7_1451300 | PF14_0488 | Ubc9 | E3 SUMO-protein ligase NSE2, putative | 2.3.2.27 |
|
| PF3D7_0801700 | MAL8P1.157 | Ulp1 | sentrin-specific protease 2, putative | 3.4.22.68 |
|
| PF3D7_1233900 | PFL1635w | Ulp1 | sentrin-specific protease 1 | 3.4.22.68 | |
| PF3D7_0420000 | PFD0970c | Ulp2 | zinc finger protein, putative |
|
|
| PF3D7_1009500 | PF10_0092 | Wss1 | metalloprotease | 3.4.24.- |
|
Total number of related proteins: 1
| # | PFID | Formal Name |
|---|---|---|
| 1 | PFD0970c | zinc finger protein, putative |
Total number of related proteins: 1
| # | PFID | Formal Name |
|---|---|---|
| 1 |
PFE0285c
|
small ubiquitin-related modifier |
Total number of related proteins: 2
| # | PFID | Formal Name |
|---|---|---|
| 1 | MAL8P1.157 | sentrin-specific protease 2, putative |
| 2 | PFL1635w | sentrin-specific protease 1 |
Total number of related proteins: 2
| # | PFID | Formal Name |
|---|---|---|
| 1 |
PFI0740c
|
SUMO-conjugating enzyme UBC9 |
| 2 | PF14_0488 | E3 SUMO-protein ligase NSE2, putative |
Total number of related proteins: 1
| # | PFID | Formal Name |
|---|---|---|
| 1 | PF10_0092 | metalloprotease |
Total number of related proteins: 1
| # | PFID | Formal Name |
|---|---|---|
| 1 | PF11_0457 | SUMO-activating enzyme subunit 1 |
Total number of related proteins: 1
| # | PFID | Formal Name |
|---|---|---|
| 1 |
PFL1790w
|
SUMO-activating enzyme subunit 2 |
Total number of related proteins: 1
| # | PFID | Formal Name |
|---|---|---|
| 1 | MAL13P1.302 | E3 SUMO-protein ligase PIAS, putative |