Malaria Parasite Metabolic Pathways
Drugs affecting pathway with unknown specific target
| Drug Name | PubMed Articles (year of publication) |
|---|---|
| Cytochalasin d | |
| Jasplankinolide | |
| Kakeromamide B | |
| Latrunculin a | |
| Violacein |
Actin and filaments map details
| PFID | PFID Old | Annotation | Formal Annotation | EC | Transcript |
|---|---|---|---|---|---|
PF3D7_0503400
|
PFE0165w | Actin-depolymerizing factor (ADF) Cofilin | actin-depolymerizing factor 1 |
|
|
| PF3D7_1361400 | PF13_0326 | Actin-depolymerizing factor (ADF) Cofilin | actin-depolymerizing factor 2 |
|
|
| PF3D7_1110700 | PF11_0114 | ALP1 | actin-like protein, putative |
|
|
| PF3D7_1103600 | PF11_0047 | ALP2a | actin-like protein, putative |
|
|
| PF3D7_0505200 | PFE0255w | ALP2b | actin-like protein, putative |
|
|
| PF3D7_0728200 | MAL7P1.153 | ALP3 | actin-like protein, putative |
|
|
| PF3D7_0910700 | PFI0520w | ALP5a | actin-like protein, putative |
|
|
| PF3D7_0409900 | PFD0487c | ALP5b | actin-like protein, putative |
|
|
| PF3D7_1118800 | PF11_0195 | ARC40 | actin-related protein 2/3 complex subunit 1, putative |
|
|
| PF3D7_0103800 | PFA0190c | Arp1 | actin-related protein arp1, putative |
|
|
|
PF3D7_1422800
|
PF14_0218 | ARP4a | actin-related protein ARP4 |
|
|
|
PF3D7_0719300
|
PF07_0077 | ARP6 | actin-related protein arp6 |
|
|
| PF3D7_0105300 | PFA0260c | CAP-like | cyclase-associated protein | ||
| PF3D7_0517600 | PFE0880c | Capping protein | F-actin-capping protein subunit beta, putative |
|
|
| PF3D7_0528500 | PFE1420w | Capping protein | F-actin-capping protein subunit alpha, putative |
|
|
|
PF3D7_0309000
|
PFC0380w | Chronophin | dual specificity protein phosphatase | 3.1.3.48 |
|
|
PF3D7_1455100
|
PF14_0524 | Chronophin | protein tyrosine phosphatase, putative | 3.1.3.48 |
|
PF3D7_1246900
|
PFL2250c | Cophilin kinase | RAC-beta serine/threonine protein kinase | 2.7.11.1 |
|
|
PF3D7_1337800
|
PF13_0211 | Cophilin kinase | calcium-dependent protein kinase 5, CDPK5 | 2.7.11.1 |
|
|
PF3D7_1251200
|
PFL2460w | Coronin | coronin |
|
|
| PF3D7_0623100 | PFF1110c | Coronin binding protein | nuclear polyadenylated rna-binding protein nab2 |
|
|
| PF3D7_1114900 | PF11_0158 | Filamin | filamin domain-containing protein, putative |
|
|
|
PF3D7_0530900
|
PFE1545c | Formin dimer | formin 1 |
|
|
|
PF3D7_1219000
|
PFL0925w | Formin dimer | formin 2 |
|
|
| PF3D7_1403800 | PF14_0035 | Formin dimer | nuclear formin-like protein misfit, putative |
|
|
| PF3D7_1110700 | PF11_0114 | G-actin monomer | actin-like protein, putative |
|
|
|
PF3D7_1246200
|
PFL2215w | G-actin monomer | actin I |
|
|
|
PF3D7_1412500
|
PF14_0124 | G-actin monomer | actin II |
|
|
| PF3D7_1324200 | MAL13P1.132 | Microfibril-associated Protein 1 | micro-fibrillar-associated protein, putative |
|
|
|
PF3D7_0932200
|
PFI1565w | Profilin | profilin |
|
|
| PF3D7_1007200 | PF10_0071 | rho GTPase-activating protein, putative | rho GTPase-activating protein, putative |
|
Total number of related proteins: 1
| # | PFID | Formal Name |
|---|---|---|
| 1 | PFA0190c | actin-related protein arp1, putative |
Total number of related proteins: 1
| # | PFID | Formal Name |
|---|---|---|
| 1 | PFA0260c | cyclase-associated protein |
Total number of related proteins: 2
| # | PFID | Formal Name |
|---|---|---|
| 1 |
PFC0380w
|
dual specificity protein phosphatase |
| 2 |
PF14_0524
|
protein tyrosine phosphatase, putative |
Total number of related proteins: 1
| # | PFID | Formal Name |
|---|---|---|
| 1 | PFD0487c | actin-like protein, putative |
Total number of related proteins: 2
| # | PFID | Formal Name |
|---|---|---|
| 1 |
PFE0165w
|
actin-depolymerizing factor 1 |
| 2 | PF13_0326 | actin-depolymerizing factor 2 |
Total number of related proteins: 1
| # | PFID | Formal Name |
|---|---|---|
| 1 | PFE0255w | actin-like protein, putative |
Total number of related proteins: 2
| # | PFID | Formal Name |
|---|---|---|
| 1 | PFE0880c | F-actin-capping protein subunit beta, putative |
| 2 | PFE1420w | F-actin-capping protein subunit alpha, putative |
Total number of related proteins: 3
| # | PFID | Formal Name |
|---|---|---|
| 1 |
PFE1545c
|
formin 1 |
| 2 |
PFL0925w
|
formin 2 |
| 3 | PF14_0035 | nuclear formin-like protein misfit, putative |
Total number of related proteins: 1
| # | PFID | Formal Name |
|---|---|---|
| 1 | PFF1110c | nuclear polyadenylated rna-binding protein nab2 |
Total number of related proteins: 1
| # | PFID | Formal Name |
|---|---|---|
| 1 |
PF07_0077
|
actin-related protein arp6 |
Total number of related proteins: 1
| # | PFID | Formal Name |
|---|---|---|
| 1 | MAL7P1.153 | actin-like protein, putative |
Total number of related proteins: 1
| # | PFID | Formal Name |
|---|---|---|
| 1 | PFI0520w | actin-like protein, putative |
Total number of related proteins: 1
| # | PFID | Formal Name |
|---|---|---|
| 1 |
PFI1565w
|
profilin |
Total number of related proteins: 1
| # | PFID | Formal Name |
|---|---|---|
| 1 | PF10_0071 | rho GTPase-activating protein, putative |
Total number of related proteins: 1
| # | PFID | Formal Name |
|---|---|---|
| 1 | PF11_0047 | actin-like protein, putative |
Total number of related proteins: 1
| # | PFID | Formal Name |
|---|---|---|
| 1 | PF11_0114 | actin-like protein, putative |
Total number of related proteins: 3
| # | PFID | Formal Name |
|---|---|---|
| 1 | PF11_0114 | actin-like protein, putative |
| 2 |
PFL2215w
|
actin I |
| 3 |
PF14_0124
|
actin II |
Total number of related proteins: 1
| # | PFID | Formal Name |
|---|---|---|
| 1 | PF11_0158 | filamin domain-containing protein, putative |
Total number of related proteins: 1
| # | PFID | Formal Name |
|---|---|---|
| 1 | PF11_0195 | actin-related protein 2/3 complex subunit 1, putative |
Total number of related proteins: 2
| # | PFID | Formal Name |
|---|---|---|
| 1 |
PFL2250c
|
RAC-beta serine/threonine protein kinase |
| 2 |
PF13_0211
|
calcium-dependent protein kinase 5, CDPK5 |
Total number of related proteins: 1
| # | PFID | Formal Name |
|---|---|---|
| 1 |
PFL2460w
|
coronin |
Total number of related proteins: 1
| # | PFID | Formal Name |
|---|---|---|
| 1 | MAL13P1.132 | micro-fibrillar-associated protein, putative |
Total number of related proteins: 1
| # | PFID | Formal Name |
|---|---|---|
| 1 |
PF14_0218
|
actin-related protein ARP4 |