Activation of the calcium and cAMP signaling pathway by melatonin

Online articles related to Activation of the calcium and cAMP signaling pathway by melatonin retrieved from PubMed

Drugs affecting pathway with unknown specific target

Drug Name	PubMed Articles (year of publication)
Dpb162-AE	Blocking IP 3 signal transduction pathways inhibits melatonin-induced Ca 2+ signals and impairs P. falciparum development and proliferation in erythrocytes
Dpb163-AE	Blocking IP 3 signal transduction pathways inhibits melatonin-induced Ca 2+ signals and impairs P. falciparum development and proliferation in erythrocytes
Luzindole	Products of tryptophan catabolism induce Ca2+ release and modulate the cell cycle of Plasmodium falciparum malaria parasites An interplay between 2 signaling pathways: melatonin-cAMP and IP3-Ca2+ signaling pathways control intraerythrocytic development of the malaria parasite Plasmodium falciparum
Melatonin	Melatonin and IP3-induced Ca2+ release from intracellular stores in the malaria parasite Plasmodium falciparum within infected red blood cells Flow cytometry as a tool for analyzing changes in Plasmodium falciparum cell cycle following treatment with indol compounds Effects of melatonin derivatives on human malaria parasite Plasmodium falciparum
Methyl [2-(1h-indol-3-yl)ethyl]carbamate	Synthetic indole and melatonin derivatives exhibit antimalarial activity on the cell cycle of the human malaria parasite Plasmodium falciparum
Methyl [2-(5-methoxy-1h-indol-3-yl)ethyl]carbamate	Synthetic indole and melatonin derivatives exhibit antimalarial activity on the cell cycle of the human malaria parasite Plasmodium falciparum
N(1)-acetyl-n(2)-formyl-5-methoxykynuramine	N1-acetyl-N2-formyl-5-methoxykynuramine modulates the cell cycle of malaria parasites
N-(2-(1h-indol-3-yl)ethyl)acetamide	Synthetic indole and melatonin derivatives exhibit antimalarial activity on the cell cycle of the human malaria parasite Plasmodium falciparum
N-(3,5-dichlorophenyl)-2-methyl-3-nitro-benzamide.	Synthetic indole and melatonin derivatives exhibit antimalarial activity on the cell cycle of the human malaria parasite Plasmodium falciparum
N-[2-(1h-indol-3-yl)ethyl]benzamide	Synthetic indole and melatonin derivatives exhibit antimalarial activity on the cell cycle of the human malaria parasite Plasmodium falciparum
N-[2-(1h-indol-3-yl)ethyl]butanamide	Synthetic indole and melatonin derivatives exhibit antimalarial activity on the cell cycle of the human malaria parasite Plasmodium falciparum
N-[2-(1h-indol-3-yl)ethyl]hexanamide	Synthetic indole and melatonin derivatives exhibit antimalarial activity on the cell cycle of the human malaria parasite Plasmodium falciparum
N-[2-(5-methoxy-1h-indol-3-yl)ethyl]benzamide	Synthetic indole and melatonin derivatives exhibit antimalarial activity on the cell cycle of the human malaria parasite Plasmodium falciparum
N-[2-(5-methoxy-1h-indol-3-yl)ethyl]hexanamide	Synthetic indole and melatonin derivatives exhibit antimalarial activity on the cell cycle of the human malaria parasite Plasmodium falciparum
N-acetyl-serotonin	Flow cytometry as a tool for analyzing changes in Plasmodium falciparum cell cycle following treatment with indol compounds
Serotonin	Flow cytometry as a tool for analyzing changes in Plasmodium falciparum cell cycle following treatment with indol compounds
Thapsigargin	Melatonin and IP3-induced Ca2+ release from intracellular stores in the malaria parasite Plasmodium falciparum within infected red blood cells
Tryptamine	Flow cytometry as a tool for analyzing changes in Plasmodium falciparum cell cycle following treatment with indol compounds
U73122	Products of tryptophan catabolism induce Ca2+ release and modulate the cell cycle of Plasmodium falciparum malaria parasites

Activation of the calcium and cAMP signaling pathway by melatonin map details

PFID	PFID Old	Annotation	Formal Annotation	EC	Transcript
PF3D7_0802600	MAL8P1.150	adenylyl cyclase	Adenylyl cyclase, Acb	4.6.1.1
PF3D7_1145400	PF11_0465	DYN1	dynamin-like protein
PF3D7_1037500	PF10_0368	DYN2	dynamin-like protein
PF3D7_1325600	MAL13P1.139	FIS1	mitochondrial fission 1 protein, putative
PF3D7_1444500	PF14_0423	PfeIK1	eukaryotic initiation factor 2alpha kinase 1	2.7.11.1
PF3D7_1468100	PF14_0649	PfMORC	MORC family protein
PF3D7_1123100	PF11_0242	PfPK7	calcium-dependent protein kinase 7	2.7.11.17
PF3D7_1013500	PF10_0132	Phospholipase C	phosphoinositide-specific phospholipase C	3.1.4.11
PF3D7_0934800	PFI1685w	Protein kinase A	cAMP-dependent protein kinase catalytic subunit	2.7.11.11
PF3D7_0422800	PFD1075w	receptor	serpentine receptor 12, putative

Total number of related proteins: 1

#	PFID	Formal Name
1	PFD1075w	serpentine receptor 12, putative

Total number of related proteins: 1

#	PFID	Formal Name
1	MAL8P1.150	Adenylyl cyclase, Acb

Total number of related proteins: 1

#	PFID	Formal Name
1	PFI1685w	cAMP-dependent protein kinase catalytic subunit

Total number of related proteins: 1

#	PFID	Formal Name
1	PF10_0132	phosphoinositide-specific phospholipase C

Total number of related proteins: 1

#	PFID	Formal Name
1	PF10_0368	dynamin-like protein

Total number of related proteins: 1

#	PFID	Formal Name
1	PF11_0242	calcium-dependent protein kinase 7

Total number of related proteins: 1

#	PFID	Formal Name
1	PF11_0465	dynamin-like protein

Total number of related proteins: 1

#	PFID	Formal Name
1	MAL13P1.139	mitochondrial fission 1 protein, putative

Total number of related proteins: 1

#	PFID	Formal Name
1	PF14_0423	eukaryotic initiation factor 2alpha kinase 1

Total number of related proteins: 1

#	PFID	Formal Name
1	PF14_0649	MORC family protein