|
Proteins predicted to be involved in cell cycle regulatory network |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Cai H, Hong C, Lilburn TG, Rodriguez AL, Chen S, Gu J, Kuang R, Wang Y. A. novel subnetwork alignment approach predicts new components of the cell cycle regulatory apparatus in Plasmodium falciparum. BMC Bioinformatics. 2013;14 Suppl 12:S2. PMID: 24267797 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Functional category |
PfID |
|
|
Annotation |
EC# |
Transcript |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 15937 |
Cyclin |
PF3D7_1227500 |
|
|
protein soc2, putative |
|
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 15901 |
Cell differentiation |
PF3D7_0507600 |
|
|
protein caf40, putative |
|
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 15902 |
Chromosome organization |
PF3D7_0509100 |
|
 |
structural maintenance of chromosomes protein 4 |
|
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 15924 |
|
PF3D7_1105100 |
|
|
histone H2B |
|
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 15942 |
Mitosis |
PF3D7_1309400 |
|
|
HORMA domain protein, putative |
|
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 15910 |
DNA repair |
PF3D7_0726300 |
|
|
DNA mismatch repair protein PMS1, putative |
|
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 15921 |
|
PF3D7_1011700 |
|
|
DNA repair protein RAD23, putative |
|
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 15913 |
|
PF3D7_0803400 |
|
|
DNA repair and recombination protein RAD54, putative |
3.6.4.12 |
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 15906 |
DNA replication |
PF3D7_0705400 |
|
|
DNA replication licensing factor MCM7 |
|
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 15934 |
|
PF3D7_1211700 |
|
|
DNA replication licensing factor MCM5, putative |
|
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 33705 |
|
PF3D7_0705300 |
 |
|
mediator of RNA polymerase ii transcription subunit 10, putative |
|
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 15904 |
|
PF3D7_0527000 |
|
|
DNA replication licensing factor MCM3, putative |
1.3.3.6 |
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 15908 |
Regulation of cell cycle |
PF3D7_0711000 |
|
|
AAA family ATPase, CDC48 subfamily |
3.6.4.6 |
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 15941 |
|
PF3D7_1239700 |
|
|
ATP-dependent zinc metalloprotease FTSH 1 |
3.4.24.- |
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 15896 |
Protein phosphorylation |
PF3D7_0302100 |
|
|
serine/threonine protein kinase |
2.7.11.1 |
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 15944 |
|
PF3D7_1356800 |
|
|
serine/threonine protein kinase ark3, putative |
2.7.11.1 |
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 15945 |
|
PF3D7_1431500 |
|
|
mitogen-activated protein kinase 1 |
2.7.11.24 |
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 24346 |
|
PF3D7_0317200 |
|
|
cdc2-related protein kinase 4 |
2.7.11.22 |
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 15930 |
|
PF3D7_1145200 |
|
|
serine/threonine protein kinase, putative |
2.7.11.1 |
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 15925 |
|
PF3D7_1114700 |
|
|
cyclin-dependent-like kinase clk3 |
2.7.11.1 |
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 15927 |
|
PF3D7_1122800 |
|
|
calcium-dependent protein kinase 6 |
2.7.11.13 |
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 15938 |
|
PF3D7_1228300 |
|
|
NIMA related kinase 1 |
2.7.11.1 |
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 15946 |
Proteolysis |
PF3D7_1454400 |
|
|
aminopeptidase P |
3.4.11.9 |
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 20935 |
|
PF3D7_1337000 |
|
|
mitochondrial intermediate peptidase, putative |
3.4.24.59 |
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 15939 |
|
PF3D7_1233900 |
|
|
sentrin-specific protease 1 |
3.4.22.68 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 15923 |
|
PF3D7_1015300 |
|
|
methionine aminopeptidase 1b, putative |
3.4.11.18 |
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 15912 |
Cytoskeleton |
PF3D7_0803200 |
|
|
filament assembling protein, putative |
|
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 15918 |
Heat shock |
PF3D7_0917900 |
|
|
PfHsp70-2 |
|
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 15933 |
|
PF3D7_1211400 |
|
|
heat shock protein DNAJ homologue Pfj4 |
|
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 15928 |
|
PF3D7_1134000 |
|
|
PfHsp70-3 |
|
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 15926 |
|
PF3D7_1118200 |
|
|
heat shock protein 90, putative |
|
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 15907 |
|
PF3D7_0708400 |
|
|
heat shock protein 90 |
|
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 15915 |
|
PF3D7_0818900 |
|
|
PfHsp70-1 |
|
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 15893 |
|
PF3D7_0213100 |
|
|
protein SIS1 |
|
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 15917 |
|
PF3D7_0907400 |
|
|
ATP-dependent protease ATPase subunit ClpY |
|
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 15895 |
Pathogenesis |
PF3D7_0300100 |
|
|
erythrocyte membrane protein 1, PfEMP1 |
|
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 15916 |
|
PF3D7_0900100 |
|
|
erythrocyte membrane protein 1, PfEMP1 |
|
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 15899 |
|
PF3D7_0400100 |
|
|
erythrocyte membrane protein 1, PfEMP1 |
|
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 15914 |
|
PF3D7_0809100 |
|
|
erythrocyte membrane protein 1, PfEMP1 |
|
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 15935 |
|
PF3D7_1219300 |
|
|
erythrocyte membrane protein 1, PfEMP1 |
|
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 15931 |
|
PF3D7_1200100 |
|
|
erythrocyte membrane protein 1, PfEMP1 |
|
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 15894 |
|
PF3D7_0223500 |
|
|
erythrocyte membrane protein 1, PfEMP1 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 15919 |
|
PF3D7_0937800 |
|
|
erythrocyte membrane protein 1, PfEMP1 |
|
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 15897 |
Microtubule cytoskeleton organization and activity |
PF3D7_0303500 |
|
|
spindle pole body protein, putative |
|
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 15909 |
|
PF3D7_0724900 |
|
|
kinesin-20, putative |
|
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 15922 |
Transcriptional regulation |
PF3D7_1014600 |
|
|
transcriptional coactivator ADA2 |
|
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 15900 |
|
PF3D7_0420300 |
|
|
AP2 domain transcription factor |
|
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 23750 |
|
PF3D7_1222600 |
|
|
AP2 domain transcription factor AP-G |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 23759 |
|
PF3D7_1143100 |
|
|
AP2 domain transcription factor AP2-O |
|
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 23600 |
|
PF3D7_0516800 |
|
|
AP2 domain transcription factor AP2-O2, putative |
|
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 23685 |
|
PF3D7_0730300 |
|
|
AP2 domain transcription factor AP2-L, putative |
|
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 27568 |
|
PF3D7_1007700 |
|
|
AP2 domain transcription transcription factor AP2-I |
|
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 15940 |
|
PF3D7_1239200 |
|
|
transcription factor with AP2 domain(s) |
|
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 25568 |
|
PF3D7_1209300 |
|
|
telomere repeat-binding zinc finger protein, putative |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Drugs affecting pathway with unknown specific target