Genes whose expression is highly positively or negatively correlated with pfcrt or pfmdr1
Adjalley SH, Scanfeld D, Kozlowski E, Llinás M, Fidock DA. Genome-wide transcriptome profiling reveals functional networks involving the Plasmodium falciparum drug resistance transporters PfCRT and PfMDR1.
$ Genes whose expression is highly correlated to that of both pfcrt and pfmdr1
Previous Gene ID Gene ID Annotation E.C# Transcript
DNA/RNA metabolism PFB0715w PF3D7_0215700 DNA-directed RNA polymerase II subunit RPB2 2.7.7.6
PFD1060w PF3D7_0422500 pre-mRNA-splicing helicase BRR2, putative 3.6.4.13
PFE0660c PF3D7_0513300
purine nucleoside phosphorylase 2.4.2.1
PFF1150w PF3D7_0623900 ribonuclease H2 subunit A, putative 3.1.26.4
PF11_0280 PF3D7_1126900 small nuclear ribonucleoprotein F, putative
PF14_0207 PF3D7_1421400 DNA-directed RNA polymerase III subunit RPC6, putative 2.7.7.6
PF14_0256 PF3D7_1427800
exosome complex exonuclease RRP41, putative 3.1.13.1
Translation PF11_0270 PF3D7_1126000
threonine--tRNA ligase 6.1.1.3
PF11_0313 PF3D7_1130200
60S ribosomal protein P0
PF13_0178 PF3D7_1332800 eukaryotic translation initiation factor 6, putative
PF13_0354 PF3D7_1367700
alanine--tRNA ligase 6.1.1.7
PF14_0428 PF3D7_1445100 histidine--tRNA ligase, putative 6.1.1.21
PFL0210c PF3D7_1204300
eukaryotic translation initiation factor 5A
PF14_0430 PF3D7_1445300 ribosomal protein S29, mitochondrial, putative
PF08_0053 PF3D7_0819100 BRIX domain, putative
PF07_0122 PF3D7_0729400 ribosome biogenesis protein BRX1 homolog, putative
Redox MAL7P1.88 PF3D7_0717900
thioredoxin-like protein
MAL7P1.159 PF3D7_0729200
1-cys peroxiredoxin 1.11.1.15
PFI1170c PF3D7_0923800
thioredoxin reductase 1.8.1.9
PF14_0368 PF3D7_1438900
thioredoxin peroxidase 1 1.11.1.15
Metabolic enzymes PFC0430w PF3D7_0310300 phosphoglycerate mutase, putative 5.4.2.11
PF10_0155 PF3D7_1015900
enolase 4.2.1.11
PF10_0325 PF3D7_1033400
haloacid dehalogenase-like hydrolase 3.8.1.-
PF13_0141 PF3D7_1324900
L-lactate dehydrogenase 1.1.1.27
PF14_0664 PF3D7_1469600
acetyl-coa carboxylase 6.3.4.14
PF10_0121 PF3D7_1012400
hypoxanthine-guanine phosphoribosyltransferase 2.4.2.8
Protein Modifications/Processing PFB0605w PF3D7_0213400
protein kinase 7 2.7.11.1
PF11_0156 PF3D7_1114700
cyclin-dependent-like kinase clk3 2.7.11.1
PFL0080c PF3D7_1201600 NIMA related kinase 3 2.7.11.1
PFI1135c PF3D7_0923100
OTU-like cysteine protease, putative 3.4.22.-
Protein Folding/Trafficking PFD0880w PF3D7_0418200 eukaryotic translation initiation factor 3 subunit m, putative
PF08_0032 PF3D7_0823800 DnaJ protein, putative
PF13_0036 PF3D7_1307200 DnaJ protein, putative
PFL2425w PF3D7_1250500 AP-3 complex subunit sigma, putative
PFF0330w PF3D7_0606700 coatomer alpha subunit, putative
MAL7P1.89 PF3D7_0718000
dynein heavy chain, putative
PFI0150c PF3D7_0903100 protein RER1, putative
Transporters/Components of the digestive vacuole PFA0160c PF3D7_0103200
nucleoside transporter 4, NT4
PFD0895c PF3D7_0418500 trafficking protein particle complex subunit 3, putative
PFE0965c PF3D7_0519200
V-type proton ATPase 16 kDa proteolipid subunit 3.6.3.14
PFE1150w PF3D7_0523000
multidrug resistance protein 1. MDR1, IP3 receptor 3.6.3.44
PFF0690c PF3D7_0614300 major facilitator superfamily-related transporter, MFR1
MAL7P1.27 PF3D7_0709000
chloroquine resistance transporter
PF08_0098 PF3D7_0810200 ABC1 family, putative, ABCK1
PF10_0366 PF3D7_1037300
ADP, ATP carrier protein 1, aac1
PF11_0334 PF3D7_1132500 amino acid transporter, putative
PF13_0252 PF3D7_1347200
nucleoside transporter 1, NT1
MAL13P1.271 PF3D7_1354400 V-type proton ATPase 21 kDa proteolipid subunit, putative 3.6.3.14
PF14_0321 PF3D7_1434000
CCR4-associated factor 16, putative
PF14_0541 PF3D7_1456800
V-type H(+)-translocating pyrophosphatase, putative, VP1 3.6.1.1
PF11_0310 PF3D7_1129900
apicomplexan amino acid transporter apiat4
PFF0825c PF3D7_0617000
mitochondrial import receptor subunit TOM40, putative
PF14_0517 PF3D7_1454400
aminopeptidase P 3.4.11.9
PF14_0678 PF3D7_1471100
exported protein 2
Genes whose expression is highly anti-correlated to that of both pfcrt and pfmdr1
Gene ID Previous Gene ID
DNA/RNA metabolism PF07_0083 PF3D7_0720100 pre-rRNA-processing protein ESF2, putative
PF14_0070 PF3D7_1407300 pre-mRNA-splicing factor 38B, putative
PFD0450c PF3D7_0409100 U4/U6 small nuclear ribonucleoprotein PRP31, putative
PFE1240w PF3D7_0524900 S-adenosyl-l-methionine-dependent trna 4-demethylwyosine synthase, putative 4.1.3.44
PFF0500c PF3D7_0610100 pre-mRNA-splicing factor SLU7, putative
PFL0355c PF3D7_1207100 pre-rRNA-processing protein esf1, putative
PF13_0013 PF3D7_1302600
deoxyhypusine hydroxylase 1.14.99.29
PF11_0264 PF3D7_1125300
DNA-directed RNA polymerase 2.7.7.6
PF13_0040 PF3D7_1307600
DNA-directed RNA polymerase subunit alpha, putative 2.7.7.6
PF14_0478 PF3D7_1450300
NADPH--cytochrome P450 reductase, putative
PF08_0111 PF3D7_0807100
parasite specific helicase 3 3.6.4.13
PF10_0209 PF3D7_1021500 ATP-dependent RNA helicase ROK1, putative 3.6.4.13
PFA0290w PF3D7_0105900 3'-5' exonuclease, putative 3.1.11.1
PFF0535c PF3D7_0610900 transcription elongation factor SPT5, putative
PFF0560c PF3D7_0611400
swi/snf-related matrix-associated actin-dependent regulator of chromatin
PFF0860c PF3D7_0617800
histone H2A
PFF1135w PF3D7_0623600 splicing factor-like protein, putative
PFE0430w PF3D7_0508700 pre-mRNA-processing ATP-dependent RNA helicase PRP5, putative 3.6.4.13
PF10_0327 PF3D7_1033600 pre-mRNA-splicing factor cef1, putative
PF14_0218 PF3D7_1422800
actin-related protein ARP4
PFA0555c PF3D7_0111500
UMP-CMP kinase, putative 2.7.4.14
Translation MAL7P1.81 PF3D7_0716800
eukaryotic translation initiation factor 3 subunit I, putative
PF07_0067 PF3D7_0716100 protein SDA1, putative
PFD0780w PF3D7_0416100
glutamyl-tRNA(Gln) amidotransferase subunit A 6.3.5.7
PFD0990w PF3D7_0420400
ribosome-recycling factor
PFC0405c PF3D7_0309700 SECIS-binding protein 2, putative
PF14_0447 PF3D7_1446900 glutaminyl-peptide cyclotransferase, putative 2.3.2.5
Protein Catabolism PF10_0174 PF3D7_1017900 26S proteasome regulatory subunit p55, putative 3.4.25.1
PF08_0067 PF3D7_0815700
apicoplast ubiquitin-like protein aubl
PF13_0096 PF3D7_1317000 U4/U6.U5 tri-snRNP-associated protein 2, putative
PFI0225w PF3D7_0904600 ubiquitin specific protease, putative 3.4.19.12
PFD0680c PF3D7_0413900 ubiquitin carboxyl-terminal hydrolase 13, putative 3.4.19.12
PFD0665c PF3D7_0413600
26S protease regulatory subunit 6B, putative; 26S proteasome AAA-ATPase subunit RPT3 3.6.4.8
PFC0581w PF3D7_0314000 hsp20-like chaperone, putative
Transporters PF13_0019 PF3D7_1303500
sodium/hydrogen exchanger, Na+, H+ antiporter NHE
PF13_0271 PF3D7_1352100
ABC transporter B family member 6, putative, ABCB6
Metabolic Enzymes PFF0680c PF3D7_0614000 thiamine-phosphate synthase, putative 2.5.1.3
PF11_0407 PF3D7_1139700 adrenodoxin reductase, putative 1.18.1.2
PFD0660w PF3D7_0413500 phosphoglucomutase-2 5.4.2.2
PF13_0121 PF3D7_1320800
dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex 2.3.1.61
PFI1680w PF3D7_0934700 UBX domain, putative
Kinases PF11_0227 PF3D7_1121900
3-phosphoinositide-dependent protein kinase 1 2.7.11.1
PF11_0242 PF3D7_1123100
calcium-dependent protein kinase 7 2.7.11.17
PF14_0143 PF3D7_1414500
atypical protein kinase, ABC-1 family, putative 1.14.13.-
PFA0555c PF3D7_0111500
UMP-CMP kinase, putative 2.7.4.14
Cell-related functions PF14_0673 PF3D7_1470600
RAP21
PFL0975w PF3D7_1220300 cell cycle associated protein, putative
MAL8P1.132 PF3D7_0806600 kinesin-like protein, putative
Unknown Function PFL2510w PF3D7_1252200
chitinase 3.2.1.14
MAL8P1.96 PF3D7_0813200 CS domain protein, putative
PF10_0326 PF3D7_1033500 WD repeat-containing protein 70, putative
PF11_0243 PF3D7_1123200 F-box protein FBXL2, putative
PFI1060w PF3D7_0921600 tetratricopeptide repeat protein, putative
PF13_0050 PF3D7_1309400 HORMA domain protein, putative
MAL13P1.395 PF3D7_1344100 tbc domain-containing protein, putative
Online articles related to Genes whose expression is highly positively or negatively correlated with pfcrt or pfmdr1 retrieved from PubMed