Malaria Parasite Metabolic Pathways
Drugs affecting pathway with unknown specific target
| Drug Name | PubMed Articles (year of publication) |
|---|---|
| Farnesol | |
| Limonene | |
| Linalool | |
| Nerolidol | |
| SID92126115 | |
| Suggested target |
Dolichol metabolism map details
| PFID | PFID Old | Annotation | Formal Annotation | EC | Transcript |
|---|---|---|---|---|---|
| PF3D7_0109850 | PFA0485w | Dolichol kinase | phosphatidate cytidylyltransferase, putative |
|
|
| PF3D7_0311600 | PFC0490w | dolichyl-diphosphooligosaccharide-protein glycotransferase | dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit ost1, putative | 2.4.99.18 |
|
PF3D7_1141600
|
PF11_0427 | dolichyl-phosphate b-D-mannosyltransferase | dolichol-phosphate mannosyltransferase | 2.4.1.83 |
|
|
PF3D7_1341600
|
MAL13P1.210 | Dolichyl-phosphate-mannose-glycolipid a-mannosyltransferase | GPI mannosyltransferase 3 | 2.4.1.- |
|
| PF3D7_1010700 | PF10_0104 | dolichyl-phosphate-mannose-protein mannosyltransferase, putative | dolichyl-phosphate-mannose-protein mannosyltransferase, putative | 2.4.1.109 |
|
|
PF3D7_1147400
|
PF11_0483a | Farnesyltransferase | protein farnesyltransferase subunit beta |
|
|
|
PF3D7_0605600
|
PFF0275c | Nucleoside-P2 kinase | nucleoside diphosphate kinase, putative | 2.7.4.6 |
|
|
PF3D7_1366500
|
PF13_0349 | Nucleoside-P2 kinase | nucleoside diphosphate kinase | 2.7.4.6 |
|
|
PF3D7_0805600
|
MAL8P1.202 | Phosphatase | phosphatidic acid phosphatase 2; phospholipid phosphatase pap2 | 3.1.3.4 |
|
| PF3D7_1455900 | PF14_0791 | Polyprenol reductase | polyprenol reductase | 1.3.1.94 |
|
|
PF3D7_1147500
|
PF11_0483 | protein farnesyltransferase subunit beta | protein farnesyltransferase subunit beta | 2.5.1.58 |
|
Total number of related proteins: 1
| # | PFID | Formal Name |
|---|---|---|
| 1 | PFA0485w | phosphatidate cytidylyltransferase, putative |
Total number of related proteins: 1
| # | PFID | Formal Name |
|---|---|---|
| 1 | PFC0490w | dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit ost1, putative |
Total number of related proteins: 2
| # | PFID | Formal Name |
|---|---|---|
| 1 |
PFF0275c
|
nucleoside diphosphate kinase, putative |
| 2 |
PF13_0349
|
nucleoside diphosphate kinase |
Total number of related proteins: 1
| # | PFID | Formal Name |
|---|---|---|
| 1 |
MAL8P1.202
|
phosphatidic acid phosphatase 2; phospholipid phosphatase pap2 |
Total number of related proteins: 1
| # | PFID | Formal Name |
|---|---|---|
| 1 | PF10_0104 | dolichyl-phosphate-mannose-protein mannosyltransferase, putative |
Total number of related proteins: 1
| # | PFID | Formal Name |
|---|---|---|
| 1 |
PF11_0427
|
dolichol-phosphate mannosyltransferase |
Total number of related proteins: 1
| # | PFID | Formal Name |
|---|---|---|
| 1 |
PF11_0483a
|
protein farnesyltransferase subunit beta |
Total number of related proteins: 1
| # | PFID | Formal Name |
|---|---|---|
| 1 |
PF11_0483
|
protein farnesyltransferase subunit beta |
Total number of related proteins: 1
| # | PFID | Formal Name |
|---|---|---|
| 1 |
MAL13P1.210
|
GPI mannosyltransferase 3 |
Total number of related proteins: 1
| # | PFID | Formal Name |
|---|---|---|
| 1 | PF14_0791 | polyprenol reductase |