Model for merozoite invasion

Online articles related to Model for merozoite invasion retrieved from PubMed

Drugs affecting pathway with unknown specific target

Drug Name	PubMed Articles (year of publication)
2,3-Butanedione monoxime	Quantitative phospho-proteomics reveals the Plasmodium merozoite triggers pre-invasion host kinase modification of the red cell cytoskeleton
2-Methoxy-2-((R)-3-(4-methoxybenzyl)-2-oxothiazolidin-4-yl)- tetrahydro-2H-pyran-4-yl 2-(Thiophen-2-yl)benzoate	Truncated Latrunculins as Actin Inhibitors Targeting Plasmodium falciparum Motility and Host Cell Invasion
2-Methoxy-2-((R)-3-(4-methoxybenzyl)-2-oxothiazolidin-4-yl)- tetrahydro-2H-pyran-4-yl 2′,3′,4′,5′-tetrahydro-[1,1′-biphenyl]-2- carboxylate	Truncated Latrunculins as Actin Inhibitors Targeting Plasmodium falciparum Motility and Host Cell Invasion
Ama1-binding peptide r1	Isolation of viable Plasmodium falciparum merozoites to define erythrocyte invasion events and advance vaccine and drug development
blebbistatin	Quantitative phospho-proteomics reveals the Plasmodium merozoite triggers pre-invasion host kinase modification of the red cell cytoskeleton
CbTI–2	Caesalpinia bonduc serine proteinase inhibitor CbTI-2: Exploring the conformational features and antimalarial activity
Cytochalasin d	Isolation of viable Plasmodium falciparum merozoites to define erythrocyte invasion events and advance vaccine and drug development Quantitative phospho-proteomics reveals the Plasmodium merozoite triggers pre-invasion host kinase modification of the red cell cytoskeleton
De-N-Ac Hep	Identification of Heparin Modifications and Polysaccharide Inhibitors of Plasmodium falciparum Merozoite Invasion That Have Potential for Novel Drug Development
Dermatan sulfate	Sulfated polyanions inhibit invasion of erythrocytes by plasmodial merozoites and cytoadherence of endothelial cells to parasitized erythrocytes
Dextran sulfate	Sulfated polyanions inhibit invasion of erythrocytes by plasmodial merozoites and cytoadherence of endothelial cells to parasitized erythrocytes Identification of Heparin Modifications and Polysaccharide Inhibitors of Plasmodium falciparum Merozoite Invasion That Have Potential for Novel Drug Development
FTY720	Plasmodium falciparum ligand binding to erythrocytes induce alterations in deformability essential for invasion
graphene oxide	Graphene oxide inhibits malaria parasite invasion and delays parasitic growth in vitro
Heparan sulfate	Sulfated polyanions inhibit invasion of erythrocytes by plasmodial merozoites and cytoadherence of endothelial cells to parasitized erythrocytes
Heparin	Isolation of viable Plasmodium falciparum merozoites to define erythrocyte invasion events and advance vaccine and drug development
Imidazole	The anti-malarial activity of bivalent imidazolium salts
Imidazolium	The anti-malarial activity of bivalent imidazolium salts
Inulin sulfate	Identification of Heparin Modifications and Polysaccharide Inhibitors of Plasmodium falciparum Merozoite Invasion That Have Potential for Novel Drug Development
Meplazumab	Nonclinical safety, tolerance and pharmacodynamics evaluation for meplazumab treating chloroquine-resistant Plasmodium falciparum
NS8593	Plasmodium falciparum ligand binding to erythrocytes induce alterations in deformability essential for invasion
oxidation of the Prx2	Treatment of erythrocytes with the 2-cys peroxiredoxin inhibitor, Conoidin A, prevents the growth of Plasmodium falciparum and enhances parasite sensitivity to chloroquine
PfRH2b mAbs	PfRH2b specific monoclonal antibodies inhibit merozoite invasion
Sulfated polyanions	Sulfated polyanions inhibit invasion of erythrocytes by plasmodial merozoites and cytoadherence of endothelial cells to parasitized erythrocytes
Tlck	Isolation of viable Plasmodium falciparum merozoites to define erythrocyte invasion events and advance vaccine and drug development
waixenicin A	Plasmodium falciparum ligand binding to erythrocytes induce alterations in deformability essential for invasion
Xylan sulfate	Identification of Heparin Modifications and Polysaccharide Inhibitors of Plasmodium falciparum Merozoite Invasion That Have Potential for Novel Drug Development

Model for merozoite invasion map details

PFID	PFID Old	Annotation	Formal Annotation
PF3D7_1133400	PF11_0344	AMA1	apical membrane antigen 1
PF3D7_0930300	PFI1475w	MSP1	merozoite surface protein 1
PF3D7_0424200	PFD1150c	Rh4	reticulocyte binding protein homologue 4
PF3D7_0424100	PFD1145c	Rh5	reticulocyte binding protein homologue 5
PF3D7_0323400	PFC1045c	RIPR	Rh5 interacting protein
PF3D7_1452000	PF14_0495	RON2	rhoptry neck protein 2
PF3D7_1116000	PF11_0168	RON4	rhoptry neck protein 4
PF3D7_0817700	MAL8P1.73	RON5	rhoptry neck protein 5

Total number of related proteins: 1

#	PFID	Formal Name
1	PFC1045c	Rh5 interacting protein

Total number of related proteins: 1

#	PFID	Formal Name
1	PFD1145c	reticulocyte binding protein homologue 5

Total number of related proteins: 1

#	PFID	Formal Name
1	PFD1150c	reticulocyte binding protein homologue 4

Total number of related proteins: 1

#	PFID	Formal Name
1	MAL8P1.73	rhoptry neck protein 5

Total number of related proteins: 1

#	PFID	Formal Name
1	PFI1475w	merozoite surface protein 1

Total number of related proteins: 1

#	PFID	Formal Name
1	PF11_0168	rhoptry neck protein 4

Total number of related proteins: 1

#	PFID	Formal Name
1	PF11_0344	apical membrane antigen 1

Total number of related proteins: 1

#	PFID	Formal Name
1	PF14_0495	rhoptry neck protein 2

Malaria Parasite Metabolic Pathways

Drugs affecting pathway with unknown specific target

Model for merozoite invasion map details

Total number of related proteins: 1

Total number of related proteins: 1

Total number of related proteins: 1

Total number of related proteins: 1

Total number of related proteins: 1

Total number of related proteins: 1

Total number of related proteins: 1

Total number of related proteins: 1