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Potential Farnesylated proteins |
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Basso AD, Kirschmeier P, Bishop WR. Lipid posttranslational modifications. Farnesyl transferase inhibitors. J Lipid Res. 2006 47(1):15-31. PMID: 16278491. |
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Farnesyl protein transferase (FTase) catalyzes the transfer of a 15 carbon isoprenyl lipid from farnesyl diphosphate (FPP) onto a cysteine residue in the C-terminal CaaX box |
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CAAX motif |
PfID |
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Annotation |
EC# |
Transcript |
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| 41553 |
CSVL |
PF3D7_0109850 |
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phosphatidate cytidylyltransferase, putative |
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| 40896 |
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PF3D7_0212900 |
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arginyl-trna--protein transferase |
2.3.2.8 |
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| 40903 |
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PF3D7_0323300 |
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conserved protein, unknown function |
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| 40917 |
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PF3D7_0517900 |
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zinc finger protein, putative |
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| 40928 |
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PF3D7_0716100 |
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protein SDA1, putative |
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| 40930 |
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PF3D7_0718700 |
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conserved Plasmodium membrane protein, unknown function |
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| 40940 |
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PF3D7_0824800 |
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conserved Plasmodium membrane protein, unknown function |
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| 40942 |
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PF3D7_0832400 |
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PIR protein stevor |
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| 40947 |
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PF3D7_0908600 |
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ribosomal RNA methyltransferase, putative |
2.1.1.56 |
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| 40953 |
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PF3D7_0935800 |
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cytoadherence linked asexual protein 9 |
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| 40957 |
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PF3D7_1008400 |
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26S protease regulatory subunit 4, putative |
3.6.4.8 |
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| 40958 |
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PF3D7_1017000 |
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DNA polymerase delta catalytic subunit |
2.7.7.7 |
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| 40959 |
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PF3D7_1019500 |
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tmem94 domain-containing protein, putative |
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| 40965 |
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PF3D7_1127600 |
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CRAL/TRIO domain-containing protein, putative |
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| 40968 |
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PF3D7_1140600 |
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conserved Plasmodium protein, unknown function |
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| 40970 |
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PF3D7_1201500 |
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XPA binding protein 1, putative |
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| 40974 |
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PF3D7_1214100 |
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GPI ethanolamine phosphate transferase 3, putative |
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| 40975 |
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PF3D7_1215200 |
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peptidyl-prolyl cis-trans isomerase |
5.2.1.8 |
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| 40982 |
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PF3D7_1243800 |
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WD repeat-containing protein 82, putative |
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| 40988 |
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PF3D7_1325200 |
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lactate dehydrogenase |
1.1.1.27 |
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| 40989 |
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PF3D7_1337000 |
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mitochondrial intermediate peptidase, putative |
3.4.24.59 |
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| 41003 |
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PF3D7_1465800 |
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dynein beta chain, putative |
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| 40949 |
CSVM |
PF3D7_0917000 |
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condensin complex subunit 3, putative? cnd3 |
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| 40973 |
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PF3D7_1212300 |
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WD repeat-containing protein, putative |
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| 40993 |
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PF3D7_1408000 |
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plasmepsin II |
3.4.23.39 |
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| 41005 |
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PF3D7_1471200 |
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inorganic anion exchanger, inorganic anion antiporter, SulP |
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| 40929 |
CHLM |
PF3D7_0717400 |
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queuine tRNA-ribosyltransferase, putative |
2.4.2.29 |
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| 40919 |
CQTS |
PF3D7_0523400 |
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DnaJ protein, putative |
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| 40963 |
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PF3D7_1112600 |
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ATPase, putative |
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| 40987 |
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PF3D7_1322100 |
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set domain-containing protein 2 |
2.1.1.43 |
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| 40991 |
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PF3D7_1356400 |
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phosphatase 2A regulatory subunit-related protein, putative |
3.1.3.16 |
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| 40997 |
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PF3D7_1432500 |
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RNA methyltransferase, putative |
2.1.1.34 |
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| 40898 |
CSIM |
PF3D7_0218300 |
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rRNA methyltransferase, putative |
2.1.1.- |
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| 40901 |
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PF3D7_0310500 |
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DEAD box helicase, putative |
3.6.4.13 |
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| 40905 |
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PF3D7_0402800 |
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erythrocyte membrane protein 1 (PfEMP1), pseudogene |
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| 40923 |
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PF3D7_0629700 |
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SET domain protein, putative |
2.1.1.43 |
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| 40934 |
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PF3D7_0722600 |
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U3 small nucleolar RNA-associated protein 7, putative |
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| 40948 |
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PF3D7_0910600 |
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SNARE protein |
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| 40969 |
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PF3D7_1144500 |
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SUMO-activating enzyme subunit 1 |
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| 40978 |
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PF3D7_1229900 |
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conserved Plasmodium protein, unknown function |
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| 40979 |
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PF3D7_1233200 |
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conserved Plasmodium protein, unknown function |
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| 40893 |
CKTQ |
PF3D7_0100100 |
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erythrocyte membrane protein 1, PfEMP1 |
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| 40897 |
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PF3D7_0216100 |
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conserved Plasmodium protein, unknown function |
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| 40925 |
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PF3D7_0712000 |
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erythrocyte membrane protein 1, PfEMP1 |
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| 40933 |
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PF3D7_0722000 |
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conserved Plasmodium protein, unknown function |
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| 40943 |
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PF3D7_0900100 |
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erythrocyte membrane protein 1, PfEMP1 |
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| 40955 |
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PF3D7_0937800 |
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erythrocyte membrane protein 1, PfEMP1 |
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| 40977 |
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PF3D7_1219300 |
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erythrocyte membrane protein 1, PfEMP1 |
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| 40980 |
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PF3D7_1240300 |
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erythrocyte membrane protein 1, PfEMP1 |
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| 40981 |
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PF3D7_1240900 |
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erythrocyte membrane protein 1, PfEMP1 |
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| 40990 |
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PF3D7_1345600 |
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inner membrane complex protein |
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| 40906 |
CKVQ |
PF3D7_0403800 |
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alpha/beta hydrolase, putative |
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| 40907 |
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PF3D7_0405200 |
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cytosolically exposed rhoptry leaflet interacting protein 2 |
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| 40914 |
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PF3D7_0501800 |
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chromatin assembly factor 1 subunit a CAF1A |
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| 40920 |
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PF3D7_0533100 |
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erythrocyte membrane protein 1 PfEMP1 VAR-UPSA2 |
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| 40932 |
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PF3D7_0720000 |
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exosome complex component CSL4, putative |
3.1.13.1 |
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| 40941 |
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PF3D7_0824900 |
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conserved Plasmodium protein, unknown function |
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| 40946 |
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PF3D7_0907600 |
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translation initiation factor SUI1, putative |
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| 40951 |
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PF3D7_0926100 |
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protein kinase, putative |
2.7.11.1 |
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| 40962 |
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PF3D7_1112100 |
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conserved Plasmodium protein, unknown function |
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| 40986 |
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PF3D7_1308400 |
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conserved Plasmodium protein, unknown function |
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| 41000 |
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PF3D7_1437000 |
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N-acetyltransferase, putative |
2.3.1.1 |
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| 41006 |
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PF3D7_1471600 |
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apical polar ring protein apr2, putative |
|
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| 40952 |
CVIM |
PF3D7_0935400 |
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gametocyte development protein 1 |
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| 40964 |
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PF3D7_1122100 |
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GPI transamidase component GPI16, putative |
|
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| 40972 |
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PF3D7_1208800 |
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zinc finger protein, putative |
|
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| 41002 |
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PF3D7_1438500 |
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cleavage and polyadenylation specificity factor subunit 3, putative |
|
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| 40908 |
CVVM |
PF3D7_0405400 |
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pre-mRNA-processing-splicing factor 8, putative |
|
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| 40894 |
CKVL |
PF3D7_0106000 |
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conserved Plasmodium protein, unknown function |
|
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| 40900 |
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PF3D7_0307900 |
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conserved Plasmodium protein, unknown function |
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| 40909 |
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PF3D7_0406800 |
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ribosomal protein L25 |
|
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| 40910 |
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PF3D7_0407100 |
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methyltransferase, putative |
2.1.1.201 |
 |
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| 40913 |
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PF3D7_0421700 |
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conserved Plasmodium protein, unknown function |
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| 40916 |
|
PF3D7_0516400 |
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phosducin-like protein 1, putative |
|
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| 40922 |
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PF3D7_0626800 |
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pyruvate kinase |
2.7.1.40 |
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| 40924 |
|
PF3D7_0703900 |
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conserved Plasmodium membrane protein, unknown function |
|
 |
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| 40927 |
|
PF3D7_0715200 |
|
|
conserved Plasmodium protein, unknown function |
|
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| 40937 |
|
PF3D7_0806600 |
|
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kinesin-like protein, putative |
|
 |
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| 40939 |
|
PF3D7_0820600 |
|
|
conserved Plasmodium membrane protein, unknown function |
|
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|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 40944 |
|
PF3D7_0901100 |
|
|
rifin |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 40950 |
|
PF3D7_0918600 |
|
|
ATP-dependent DNA helicase Q1; bloom protein homolog |
3.6.4.12 |
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 40954 |
|
PF3D7_0937300 |
|
|
rifin PIR protein |
|
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 40976 |
|
PF3D7_1218600 |
|
|
arginine-tRNA ligase; arginyl-tRNA synthetase |
6.1.1.19 |
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 40983 |
|
PF3D7_1254000 |
|
|
rifin |
|
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 40984 |
|
PF3D7_1301000 |
|
|
rifin, pseudogene |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 40992 |
|
PF3D7_1402300 |
|
|
26S proteasome regulatory subunit RPN6 |
|
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 40996 |
|
PF3D7_1419600 |
|
|
conserved Plasmodium protein, unknown function |
|
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 40999 |
|
PF3D7_1434500 |
|
|
dynein-related AAA-type ATPase, putative |
3.6.4.2 |
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 41001 |
|
PF3D7_1437700 |
|
|
succinyl-CoA ligase, putative |
6.2.1.5 |
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 40895 |
CCVQ |
PF3D7_0112200 |
|
|
multidrug resistance-associated protein 1 MRP1 |
3.6.3.44 |
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 40971 |
CCVM |
PF3D7_1205100 |
|
|
O-phosphoseryl-tRNA(Sec) selenium transferase, putative |
2.9.1.2 |
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 40961 |
CCVT |
PF3D7_1103800 |
|
|
CCR4-NOT transcription complex subunit not1-g, putative |
|
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 41004 |
|
PF3D7_1468000 |
|
|
conserved Plasmodium protein, unknown function |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 40898 |
CSIM |
PF3D7_0218300 |
|
|
rRNA methyltransferase, putative |
2.1.1.- |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 40901 |
|
PF3D7_0310500 |
|
|
DEAD box helicase, putative |
3.6.4.13 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 40905 |
|
PF3D7_0402800 |
|
|
erythrocyte membrane protein 1 (PfEMP1), pseudogene |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 40923 |
|
PF3D7_0629700 |
|
|
SET domain protein, putative |
2.1.1.43 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 40934 |
|
PF3D7_0722600 |
|
|
U3 small nucleolar RNA-associated protein 7, putative |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 40948 |
|
PF3D7_0910600 |
|
|
SNARE protein |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 40969 |
|
PF3D7_1144500 |
|
|
SUMO-activating enzyme subunit 1 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 40978 |
|
PF3D7_1229900 |
|
|
conserved Plasmodium protein, unknown function |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 40979 |
|
PF3D7_1233200 |
|
|
conserved Plasmodium protein, unknown function |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 40904 |
CNLM |
PF3D7_0400300 |
|
|
rifin PIR protein |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 40912 |
|
PF3D7_0419900 |
|
|
phosphatidylinositol 4-kinase, putative |
2.7.1.67 |
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 40985 |
|
PF3D7_1302500 |
|
|
aaa domain-containing protein, putative |
|
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 40998 |
|
PF3D7_1433800 |
|
|
conserved Plasmodium protein, unknown function |
|
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 40899 |
CLIT |
PF3D7_0222700 |
|
|
rifin |
|
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 40902 |
|
PF3D7_0313400 |
|
|
conserved Plasmodium protein, unknown function |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 40911 |
|
PF3D7_0418000 |
|
|
conserved Plasmodium protein, unknown function |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 40915 |
|
PF3D7_0515700 |
|
|
glideosome-associated protein 40, putative |
|
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 40918 |
|
PF3D7_0518700 |
|
|
mRNA-binding protein PUF1 |
|
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 40921 |
|
PF3D7_0617100 |
|
|
AP-2 complex subunit alpha, putative |
|
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 40926 |
|
PF3D7_0713900 |
|
|
conserved Plasmodium protein, unknown function |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 40931 |
|
PF3D7_0719500 |
|
|
LEM3/CDC50 family protein, putative |
|
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 40935 |
|
PF3D7_0723100 |
|
|
conserved Plasmodium protein, unknown function |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 40936 |
|
PF3D7_0727000 |
|
|
vacuolar protein sorting-associated protein 53, putative |
|
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 40938 |
|
PF3D7_0815100 |
|
|
heptatricopeptide repeat and rap domain-containing protein, putative |
|
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 40945 |
|
PF3D7_0904100 |
|
|
AP-4 complex subunit epsilon, putative |
|
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 40956 |
|
PF3D7_1003700 |
|
|
mkt1 domain-containing protein, putative |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 40960 |
|
PF3D7_1034400 |
|
|
flavoprotein subunit of succinate dehydrogenase |
1.3.5.1 |
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 40966 |
|
PF3D7_1129600 |
|
|
phosphatidylinositol-4-phosphate 5-kinase, putative |
2.7.1.68 |
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 40967 |
|
PF3D7_1139900 |
|
|
ER membrane protein complex subunit 8, putative |
|
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 40994 |
|
PF3D7_1409700 |
|
|
conserved Plasmodium protein, unknown function |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 40995 |
|
PF3D7_1417600 |
|
|
ookinete surface and oocyst capsule protein oscp, putative |
|
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 41002 |
|
PF3D7_1438500 |
|
|
cleavage and polyadenylation specificity factor subunit 3, putative |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|