Glycosylphosphatidylinositol (GPI) anchor biosynthesis

Online articles related to Glycosylphosphatidylinositol (GPI) anchor biosynthesis retrieved from PubMed

Drugs affecting pathway with unknown specific target

Drug Name	PubMed Articles (year of publication)
2-deoxy-d-glucose	Inhibition of glycosyl-phosphatidylinositol biosynthesis in Plasmodium falciparum by C-2 substituted mannose analogues
Guanosine triphosphate	Biosynthesis of glycosylphosphatidylinositols of Plasmodium falciparum in a cell-free incubation system: inositol acylation is needed for mannosylation of glycosylphosphatidylinositols
Mannosamine	Developmental stage-specific biosynthesis of glycosylphosphatidylinositol anchors in intraerythrocytic Plasmodium falciparum and its inhibition in a novel manner by mannosamine Inhibition of glycosyl-phosphatidylinositol biosynthesis in Plasmodium falciparum by C-2 substituted mannose analogues
tamoxifen	Effect of tamoxifen on the sphingolipid biosynthetic pathway in the different intraerythrocytic stages of the apicomplexa Plasmodium falciparum

Glycosylphosphatidylinositol (GPI) anchor biosynthesis map details

PFID	PFID Old	Annotation	Formal Annotation	EC	Transcript
PF3D7_1141600	PF11_0427	dolichol-phosphate mannosyltransferase– PIG M	dolichol-phosphate mannosyltransferase	2.4.1.83
PF3D7_1210900	PFL0540w	dolichol-phosphate mannosyltransferase– PIG M	GPI mannosyltransferase I	2.4.1.83
PF3D7_1341600	MAL13P1.210	Dolichyl-phosphate-mannose-glycolipid a-mannosyltransferase	GPI mannosyltransferase 3	2.4.1.-
PF3D7_1247300	PFL2270w	GPI mannosyltransferase 2 – PIG V	GPI mannosyltransferase 2, putative	2.4.1.-
PF3D7_1122100	PF11_0229	GPI16	GPI transamidase component GPI16, putative
PF3D7_1128700	PF11_0298	GPI8	GPI-anchor transamidase	3.4.13.19
PF3D7_1369000	MAL13P1.348	GPI8	glycosylphosphatidylinositol anchor attachment 1 protein, putative
PF3D7_1369000	MAL13P1.348	GPI-anchor transamidase	glycosylphosphatidylinositol anchor attachment 1 protein, putative
PF3D7_1330700	MAL13P1.165	GPI-anchor transamidase – PIG-U	GPI transamidase subunit PIG-U, putative
PF3D7_0624700	PFF1190c	N-acetylglucosaminylphosphatidylinositol deacetylase	N-acetylglucosaminylphosphatidylinositol deacetylase, putative	3.5.1.89
PF3D7_0911000	PFI0535w	N-acetylglucosaminylphosphatidylinositol deacetylase	phosphatidylinositol N-acetylglucosaminyltransferase, putative	3.5.1.89
PF3D7_0618900	PFF0915w	Phosphatidylinositol N-acetylglucosaminyltransferase	phosphatidylinositol N-acetylglucosaminyltransferase subunit GPI1	2.4.1.198
PF3D7_0935300	PFI1705w	Phosphatidylinositol N-acetylglucosaminyltransferase	phosphatidylinositol N-acetylglucosaminyltransferase subunit P, putative	2.4.1.198
PF3D7_1032400	PF10_0316	Phosphatidylinositol N-acetylglucosaminyltransferase	phosphatidylinositol N-acetylglucosaminyltransferase subunit A, putative	2.4.1.198
PF3D7_1141400	PF11_0425	Phosphatidylinositol N-acetylglucosaminyltransferase	phosphatidylinositol N-acetylglucosaminyltransferase subunit H, putative	2.4.1.198
PF3D7_1214100	PFL0685w	PIG-O	GPI ethanolamine phosphate transferase 3, putative
PF3D7_0615300	PFF0740c	PIG-W	GPI-anchored wall transfer protein 1, putative

Total number of related proteins: 1

#	PFID	Formal Name
1	PFF0740c	GPI-anchored wall transfer protein 1, putative

Total number of related proteins: 4

#	PFID	Formal Name
1	PFF0915w	phosphatidylinositol N-acetylglucosaminyltransferase subunit GPI1
2	PFI1705w	phosphatidylinositol N-acetylglucosaminyltransferase subunit P, putative
3	PF10_0316	phosphatidylinositol N-acetylglucosaminyltransferase subunit A, putative
4	PF11_0425	phosphatidylinositol N-acetylglucosaminyltransferase subunit H, putative

Total number of related proteins: 2

#	PFID	Formal Name
1	PFF1190c	N-acetylglucosaminylphosphatidylinositol deacetylase, putative
2	PFI0535w	phosphatidylinositol N-acetylglucosaminyltransferase, putative

Total number of related proteins: 1

#	PFID	Formal Name
1	PF11_0229	GPI transamidase component GPI16, putative

Total number of related proteins: 2

#	PFID	Formal Name
1	PF11_0298	GPI-anchor transamidase
2	MAL13P1.348	glycosylphosphatidylinositol anchor attachment 1 protein, putative

Total number of related proteins: 2

#	PFID	Formal Name
1	PF11_0427	dolichol-phosphate mannosyltransferase
2	PFL0540w	GPI mannosyltransferase I

Total number of related proteins: 1

#	PFID	Formal Name
1	PFL0685w	GPI ethanolamine phosphate transferase 3, putative

Total number of related proteins: 1

#	PFID	Formal Name
1	PFL2270w	GPI mannosyltransferase 2, putative

Total number of related proteins: 1

#	PFID	Formal Name
1	MAL13P1.165	GPI transamidase subunit PIG-U, putative

Total number of related proteins: 1

#	PFID	Formal Name
1	MAL13P1.210	GPI mannosyltransferase 3

Total number of related proteins: 1

#	PFID	Formal Name
1	MAL13P1.348	glycosylphosphatidylinositol anchor attachment 1 protein, putative