Malaria Parasite Metabolic Pathways
Drugs affecting pathway with unknown specific target
Hemoglobin digestion map details
| PFID | PFID Old | Annotation | Formal Annotation | EC | Transcript |
|---|---|---|---|---|---|
PF3D7_1311800
|
MAL13P1.56 | Alanyl aminopeptidase | M1-family alanyl aminopeptidase | 3.4.11.2 |
|
|
PF3D7_0629500
|
PFF1430c | amino acid transporter aat1 | amino acid transporter aat1 |
|
|
|
PF3D7_1454400
|
PF14_0517 | Aminoacylproline aminopeptidase | aminopeptidase P | 3.4.11.9 |
|
|
PF3D7_1454400
|
PF14_0517 | aminopeptidase P | aminopeptidase P | 3.4.11.9 |
|
|
PF3D7_0932300
|
PFI1570c | Aspartyl aminopeptidase | M18 aspartyl aminopeptidase | 3.4.11.21 |
|
|
PF3D7_1116700
|
PF11_0174 | Dipeptidyl aminopeptidase 1 | dipeptidyl aminopeptidase 1 cathepsin C, homolog | 3.4.14.1 |
|
|
PF3D7_1247800
|
PFL2290w | Dipeptidyl aminopeptidase 1 | dipeptidyl aminopeptidase 2 | 3.4.14.1 |
|
|
PF3D7_1360800
|
PF13_0322 | Falcilysin | falcilysin | 3.4.24.- |
|
|
PF3D7_1115300
|
PF11_0161 | falcipain 2' cysteine proteinase falcipain 2b | falcipain 2' cysteine proteinase falcipain 2b | 3.4.22.- |
|
|
PF3D7_1115400
|
PF11_0162 | Falcipain 2, 3 | cysteine proteinase falcipain 3 | 3.4.22.- |
|
|
PF3D7_1115700
|
PF11_0165 | Falcipain 2, 3 | cysteine proteinase falcipain 2a falcipain 2 | 3.4.22.- |
|
|
PF3D7_1460100
|
PF14_0574 | FCP | FYVE and coiled-coil domain-containing protein |
|
|
|
PF3D7_1446800
|
PF14_0446 | Heme detoxification protein | heme detoxification protein |
|
|
|
PF3D7_1115300
|
PF11_0161 | Histo-aspartic protease | falcipain 2' cysteine proteinase falcipain 2b | 3.4.22.- |
|
|
PF3D7_0831800
|
MAL7P1.231 | HRPII | histidine-rich protein II | ||
| PF3D7_1372200 | MAL13P1.480 | HRPIII | histidine-rich protein III |
|
|
|
PF3D7_1446200
|
PF14_0439 | Leucyl aminopeptidase | M17 leucyl aminopeptidase | 3.4.11.1 |
|
| PF3D7_0527300 | PFE1360c | Methionyl aminopeptidase | methionine aminopeptidase 1a, putative | 3.4.11.18 |
|
|
PF3D7_0804400
|
MAL8P1.140 | Methionyl aminopeptidase | methionine aminopeptidase 1c, putative | 3.4.11.18 |
|
|
PF3D7_1015300
|
PF10_0150 | Methionyl aminopeptidase | methionine aminopeptidase 1b, putative | 3.4.11.18 |
|
|
PF3D7_1434600
|
PF14_0327 | Methionyl aminopeptidase | methionine aminopeptidase 2 | 3.4.11.18 |
|
|
PF3D7_1407900
|
PF14_0076 | Plasmepsin I | plasmepsin I | 3.4.23.38 |
|
|
PF3D7_1408000
|
PF14_0077 | Plasmepsin II | plasmepsin II | 3.4.23.39 |
|
|
PF3D7_1407800
|
PF14_0075 | Plasmepsin IV | plasmepsin IV | 3.4.23.- |
|
|
PF3D7_1401300
|
PF14_0015 | proline aminopeptidase | proline aminopeptidase | 3.4.11.5 |
|
|
PF3D7_0507200
|
PFE0355c | subtilisin | subtilisin-like protease 3 | 3.4.21.62 |
|
|
PF3D7_0507500
|
PFE0370c | Subtilisin | subtilisin-like protease 1 | 3.4.21.62 |
|
|
PF3D7_1136900
|
PF11_0381 | Subtilisin | subtilisin-like protease 2 | 3.4.21.62 |
|
|
PF3D7_0216400
|
PFB0750w | VPS45 | vacuolar protein sorting-associated protein 45, putative |
|
Total number of related proteins: 1
| # | PFID | Formal Name |
|---|---|---|
| 1 |
PFB0750w
|
vacuolar protein sorting-associated protein 45, putative |
Total number of related proteins: 3
| # | PFID | Formal Name |
|---|---|---|
| 1 |
PFE0355c
|
subtilisin-like protease 3 |
| 2 |
PFE0370c
|
subtilisin-like protease 1 |
| 3 |
PF11_0381
|
subtilisin-like protease 2 |
Total number of related proteins: 4
| # | PFID | Formal Name |
|---|---|---|
| 1 | PFE1360c | methionine aminopeptidase 1a, putative |
| 2 |
MAL8P1.140
|
methionine aminopeptidase 1c, putative |
| 3 |
PF10_0150
|
methionine aminopeptidase 1b, putative |
| 4 |
PF14_0327
|
methionine aminopeptidase 2 |
Total number of related proteins: 1
| # | PFID | Formal Name |
|---|---|---|
| 1 |
PFF1430c
|
amino acid transporter aat1 |
Total number of related proteins: 1
| # | PFID | Formal Name |
|---|---|---|
| 1 |
MAL7P1.231
|
histidine-rich protein II |
Total number of related proteins: 1
| # | PFID | Formal Name |
|---|---|---|
| 1 |
PFI1570c
|
M18 aspartyl aminopeptidase |
Total number of related proteins: 1
| # | PFID | Formal Name |
|---|---|---|
| 1 |
PF11_0161
|
falcipain 2' cysteine proteinase falcipain 2b |
Total number of related proteins: 1
| # | PFID | Formal Name |
|---|---|---|
| 1 |
PF11_0161
|
falcipain 2' cysteine proteinase falcipain 2b |
Total number of related proteins: 2
| # | PFID | Formal Name |
|---|---|---|
| 1 |
PF11_0162
|
cysteine proteinase falcipain 3 |
| 2 |
PF11_0165
|
cysteine proteinase falcipain 2a falcipain 2 |
Total number of related proteins: 2
| # | PFID | Formal Name |
|---|---|---|
| 1 |
PF11_0174
|
dipeptidyl aminopeptidase 1 cathepsin C, homolog |
| 2 |
PFL2290w
|
dipeptidyl aminopeptidase 2 |
Total number of related proteins: 1
| # | PFID | Formal Name |
|---|---|---|
| 1 |
MAL13P1.56
|
M1-family alanyl aminopeptidase |
Total number of related proteins: 1
| # | PFID | Formal Name |
|---|---|---|
| 1 |
PF13_0322
|
falcilysin |
Total number of related proteins: 1
| # | PFID | Formal Name |
|---|---|---|
| 1 | MAL13P1.480 | histidine-rich protein III |
Total number of related proteins: 1
| # | PFID | Formal Name |
|---|---|---|
| 1 |
PF14_0015
|
proline aminopeptidase |
Total number of related proteins: 1
| # | PFID | Formal Name |
|---|---|---|
| 1 |
PF14_0075
|
plasmepsin IV |
Total number of related proteins: 1
| # | PFID | Formal Name |
|---|---|---|
| 1 |
PF14_0076
|
plasmepsin I |
Total number of related proteins: 1
| # | PFID | Formal Name |
|---|---|---|
| 1 |
PF14_0077
|
plasmepsin II |
Total number of related proteins: 1
| # | PFID | Formal Name |
|---|---|---|
| 1 |
PF14_0439
|
M17 leucyl aminopeptidase |
Total number of related proteins: 1
| # | PFID | Formal Name |
|---|---|---|
| 1 |
PF14_0446
|
heme detoxification protein |
Total number of related proteins: 1
| # | PFID | Formal Name |
|---|---|---|
| 1 |
PF14_0517
|
aminopeptidase P |
Total number of related proteins: 1
| # | PFID | Formal Name |
|---|---|---|
| 1 |
PF14_0517
|
aminopeptidase P |
Total number of related proteins: 1
| # | PFID | Formal Name |
|---|---|---|
| 1 |
PF14_0574
|
FYVE and coiled-coil domain-containing protein |