CatalasePV5idc:VPS45VPS45 idc:Aminoacylproline aminopeptidase Aminoacylproline aminopeptidase idc:Alanyl aminopeptidase Alanyl aminopeptidase FCP Plasmepsin I idc:Methionyl aminopeptidase Methionyl aminopeptidase Aspartyl aminopeptidase proline aminopeptidase Dipeptidyl aminopeptidase 1 idc:Subtilisin Histo-aspartic protease Falcilysin Falcipain 2, 3 Putative amino acid transporter Heme detoxification protein Plasmepsin II Plasmepsin IV idc:Plasmepsin I idc:Plasmepsin II idc:FCP idc:Plasmepsin IV idc:Putative amino acid transporter idc:Dipeptidyl aminopeptidase 1 idc:pfid:PF11_0165 idc:pfid:PF11_0162 idc:Histo-aspartic protease idc:Falcilysin aminopeptidase P idc:Aspartyl aminopeptidase Subtilisin idc:Heme detoxification protein idc:aminopeptidase P Putative amino acid transporter Leucyl aminopeptidase idc:Leucyl aminopeptidase idc:proline aminopeptidase HRPII HRPIII

Online articles related to Hemoglobin digestion retrieved from PubMed

RX Drugs affecting pathway with unknown specific target

Drug Name PubMed Articles (year of publication)
(±)-moxiquindole
1,2,4-trioxolane
1-[2,8-bis(trifluoromethyl)-4-quinolyl]-2-(butylamino)ethanol
1-[2,8-bis(trifluoromethyl)-4-quinolyl]-2-(ethylamino)ethanol
1-[2,8-bis(trifluoromethyl)-4-quinolyl]-2-(octylamino)ethanol
4-Tert-butyl-2-[(tert-butylamino)methyl]-6-[5-fluoro-6-(trifluoromethyl)pyridin-3-yl]phenol
5-(4-methylsulfonylphenyl)-3-[6-(trifluoromethyl)pyridin-3-yl]pyridin-2-amine
Artemisinin
Chloroquine
Co-PPIX
Cu-PPIX
Dihydroartemisinin
E64
Fe-PPIX
GNF-Pf-5660
Halofantrine hydrochloride
JPC-3210
Mefloquine
methyl (3R,4S)-3-butyl-3-methoxy-6,6-dimethyl-dioxane-4-carboxylate
MMV000356
MMV000483
MMV000963
MMV006087
MMV006172
MMV007977
MMV011576
MMV020654
MMV665928
MMV665929
MMV665948
Mn-PPIX
Nelfinavir
Ni-PPIX
Oz277
plakortin
Protoporphyrin ix
Quinine
Tafenoquine
Torin 2
Zn-PPIX

Hemoglobin digestion map details

PFID PFID Old Annotation Formal Annotation EC Transcript
PF3D7_1311800 loop drugs MAL13P1.56 Alanyl aminopeptidase M1-family alanyl aminopeptidase 3.4.11.2 pie diagram
PF3D7_0629500 drugs PFF1430c amino acid transporter aat1 amino acid transporter aat1 pie diagram
PF3D7_1454400 loop drugs PF14_0517 Aminoacylproline aminopeptidase aminopeptidase P 3.4.11.9 pie diagram
PF3D7_1454400 loop drugs PF14_0517 aminopeptidase P aminopeptidase P 3.4.11.9 pie diagram
PF3D7_0932300 loop drugs PFI1570c Aspartyl aminopeptidase M18 aspartyl aminopeptidase 3.4.11.21 pie diagram
PF3D7_1116700 loop drugs PF11_0174 Dipeptidyl aminopeptidase 1 dipeptidyl aminopeptidase 1 cathepsin C, homolog 3.4.14.1 pie diagram
PF3D7_1247800 loop drugs PFL2290w Dipeptidyl aminopeptidase 1 dipeptidyl aminopeptidase 2 3.4.14.1 pie diagram
PF3D7_1360800 loop drugs PF13_0322 Falcilysin falcilysin 3.4.24.- pie diagram
PF3D7_1115300 loop drugs PF11_0161 falcipain 2' cysteine proteinase falcipain 2b falcipain 2' cysteine proteinase falcipain 2b 3.4.22.- pie diagram
PF3D7_1115400 loop drugs PF11_0162 Falcipain 2, 3 cysteine proteinase falcipain 3 3.4.22.- pie diagram
PF3D7_1115700 loop drugs PF11_0165 Falcipain 2, 3 cysteine proteinase falcipain 2a falcipain 2 3.4.22.- pie diagram
PF3D7_1460100 loop PF14_0574 FCP FYVE and coiled-coil domain-containing protein pie diagram
PF3D7_1446800 loop drugs PF14_0446 Heme detoxification protein heme detoxification protein pie diagram
PF3D7_1115300 loop drugs PF11_0161 Histo-aspartic protease falcipain 2' cysteine proteinase falcipain 2b 3.4.22.- pie diagram
PF3D7_0831800 loop drugs MAL7P1.231 HRPII histidine-rich protein II
PF3D7_1372200 MAL13P1.480 HRPIII histidine-rich protein III pie diagram
PF3D7_1446200 loop drugs PF14_0439 Leucyl aminopeptidase M17 leucyl aminopeptidase 3.4.11.1 pie diagram
PF3D7_0527300 PFE1360c Methionyl aminopeptidase methionine aminopeptidase 1a, putative 3.4.11.18 pie diagram
PF3D7_0804400 drugs MAL8P1.140 Methionyl aminopeptidase methionine aminopeptidase 1c, putative 3.4.11.18 pie diagram
PF3D7_1015300 drugs PF10_0150 Methionyl aminopeptidase methionine aminopeptidase 1b, putative 3.4.11.18 pie diagram
PF3D7_1434600 drugs PF14_0327 Methionyl aminopeptidase methionine aminopeptidase 2 3.4.11.18 pie diagram
PF3D7_1407900 loop drugs PF14_0076 Plasmepsin I plasmepsin I 3.4.23.38 pie diagram
PF3D7_1408000 loop drugs PF14_0077 Plasmepsin II plasmepsin II 3.4.23.39 pie diagram
PF3D7_1407800 loop drugs PF14_0075 Plasmepsin IV plasmepsin IV 3.4.23.- pie diagram
PF3D7_1401300 loop PF14_0015 proline aminopeptidase proline aminopeptidase 3.4.11.5 pie diagram
PF3D7_0507200 loop PFE0355c subtilisin subtilisin-like protease 3 3.4.21.62 pie diagram
PF3D7_0507500 loop drugs PFE0370c Subtilisin subtilisin-like protease 1 3.4.21.62 pie diagram
PF3D7_1136900 loop drugs PF11_0381 Subtilisin subtilisin-like protease 2 3.4.21.62 pie diagram
PF3D7_0216400 loop PFB0750w VPS45 vacuolar protein sorting-associated protein 45, putative pie diagram