Highest expressed genes based on mRNA abundance
Compiled from
Le Roch KG, Zhou Y, Blair PL, Grainger M, Moch JK, Haynes JD, De La Vega P, Holder AA, Batalov S, Carucci DJ, Winzeler EA. Discovery of gene function by expression profiling of the malaria parasite life cycle. Science. 2003 301(5639):1503-8. PMID: 12893887.
Foth BJ, Zhang N, Chaal BK, Sze SK, Preiser PR, Bozdech Z. Quantitative time-course profiling of parasite and host cell proteins in the human malaria parasite Plasmodium falciparum. Mol Cell Proteomics. 2011 10(8):M110.006411. PMID: 21558492;
PfID Annotation Relative mRNA abundance at trophozoite stage
26018 PF3D7_1015900
enolase 10.0
26086 PF3D7_1462800
glyceraldehyde-3-phosphate dehydrogenase 10.0
25999 PF3D7_0818900
heat shock protein 70 10.0
26005 PF3D7_0917900
heat shock protein 70 10.0
25989 PF3D7_0708400
heat shock protein 90 10.0
26047 PF3D7_1222300
endoplasmin, putative 10.0
26052 PF3D7_1311800
M1-family alanyl aminopeptidase 10.0
26058 PF3D7_1343000
phosphoethanolamine N-methyltransferase 10.0
26008 PF3D7_0922500
phosphoglycerate kinase 10.0
26000 PF3D7_0826700
receptor for activated c kinase 10.0
26087 PF3D7_1468700
eukaryotic initiation factor 4A helicase 45 10.0
26007 PF3D7_0922200
S-adenosylmethionine synthetase 10.0
26086 PF3D7_1462800
glyceraldehyde-3-phosphate dehydrogenase 10.0
26043 PF3D7_1149100 Plasmodium exported protein, unknown function 10.8
25998 PF3D7_0818200
14-3-3 protein 9.0
26049 PF3D7_1246200
actin I 9.0
26004 PF3D7_0913200 elongation factor 1-beta 9.0
26084 PF3D7_1451100
elongation factor 2 9.0
26083 PF3D7_1444800
fructose-bisphosphate aldolase 9.0
26041 PF3D7_1134000
heat shock protein 70 9.0
26034 PF3D7_1118200 heat shock protein 90, putative 9.0
26009 PF3D7_0925900
lipocalin, lcn 9.0
26055 PF3D7_1324900
L-lactate dehydrogenase 9.0
26011 PF3D7_0930300
merozoite surface protein 1 9.0
25982 PF3D7_0608800
ornithine aminotransferase 9.0
26051 PF3D7_1302100
gamete antigen 27/25 9.0
26001 PF3D7_0827900
protein disulfide isomerase 9.0
25987 PF3D7_0626800
pyruvate kinase 9.0
26082 PF3D7_1439900
triosephosphate isomerase 9.0
25964 PF3D7_0307100 40S ribosomal protein S12, putative 8.0
26039 PF3D7_1130200
60S ribosomal protein P0 8.0
26022 PF3D7_1029600
adenosine deaminase 8.0
25990 PF3D7_0708800
heat shock protein 110 8.0
26065 PF3D7_1357000
elongation factor 1-alpha 8.0
26036 PF3D7_1121600
parasitophorous vacuole membrane antigen QF 116 exported protein 1 circumsporozoite-related antigen 8.0
26068 PF3D7_1360800
falcilysin 8.0
26033 PF3D7_1117700
GTP-binding nuclear protein RAN/TC4 8.0
26023 PF3D7_1033400
haloacid dehalogenase-like hydrolase 8.0
25985 PF3D7_0624000
hexokinase 8.0
25976 PF3D7_0511000
translationally-controlled tumor protein homolog 8.0
26017 PF3D7_1015600
heat shock protein 60 8.0
26035 PF3D7_1120100
phosphoglycerate mutase, putative 8.0
26069 PF3D7_1361900
proliferating cell nuclear antigen 1 8.0
25978 PF3D7_0513300
purine nucleoside phosphorylase 8.0
26081 PF3D7_1438900
thioredoxin peroxidase 1 8.0
26019 PF3D7_1016300
glycophorin binding protein 7.0
26048 PF3D7_1226300
haloacid dehalogenase-like hydrolase, putative 7.0
26030 PF3D7_1115600
peptidyl-prolyl cis-trans isomerase 7.0
25959 PF3D7_0209800
ATP-dependent RNA helicase UAP56 7.0
26045 PF3D7_1204300
eukaryotic translation initiation factor 5A 7.0
25986 PF3D7_0626700 ATPase, putative 7.0
26016 PF3D7_1012400
hypoxanthine-guanine phosphoribosyltransferase 7.0
26044 PF3D7_1203700
nucleosome assembly protein 7.0
26073 PF3D7_1407900
plasmepsin I 7.0
25966 PF3D7_0317000 proteasome subunit alpha type-3, putative 7.0
25971 PF3D7_0419600 ran-specific GTPase-activating protein 1, putative 7.0
26053 PF3D7_1311900
V-type proton ATPase catalytic subunit A 7.0
25999 PF3D7_0818900
heat shock protein 70 6.9
26020 PF3D7_1026800
40S ribosomal protein S2 6.0
26027 PF3D7_1108600
endoplasmic reticulum-resident calcium binding protein 6.0
26088 PF3D7_1471100
exported protein 2 6.0
26031 PF3D7_1115700
cysteine proteinase falcipain 2a falcipain 2 6.0
26029 PF3D7_1115300
falcipain 2' cysteine proteinase falcipain 2b 6.0
26010 PF3D7_0929400
high molecular weight rhoptry protein 2 6.0
26026 PF3D7_1105800 conserved apicomplexan protein, unknown function 6.0
26061 PF3D7_1347500
DNA/RNA-binding protein Alba 4 6.0
26062 PF3D7_1350100
lysine--tRNA ligase 6.0
26021 PF3D7_1027300
peroxiredoxin merozoite capping protein 1 6.0
26072 PF3D7_1407800
plasmepsin IV 6.0
26063 PF3D7_1353800 proteasome subunit alpha type-4, putative 6.0
25983 PF3D7_0610800
transketolase 6.0
26084 PF3D7_1451100
elongation factor 2 5.9
26024 PF3D7_1038000 antigen UB05 5.1
26036 PF3D7_1121600
parasitophorous vacuole membrane antigen QF 116 exported protein 1 circumsporozoite-related antigen 5.0
25957 PF3D7_0108000
proteasome subunit beta type-3, putative 5.0
26038 PF3D7_1127100
deoxyuridine 5'-triphosphate nucleotidohydrolase dUTP pyrophosphatase 5.0
25995 PF3D7_0814200
DNA/RNA-binding protein Alba 1 5.0
25980 PF3D7_0532100
early transcribed membrane protein 5 5.0
26078 PF3D7_1434300
Hsp70/Hsp90 organizing protein 5.0
26060 PF3D7_1346300
DNA/RNA-binding protein Alba 2 5.0
26071 PF3D7_1403900 serine/threonine protein phosphatase cpped1 5.0
26074 PF3D7_1408000
plasmepsin II 5.0
26075 PF3D7_1408100
plasmepsin III histo-aspartic protease 5.0
26013 PF3D7_0932200
profilin 5.0
26089 PF3D7_1474800 proteasome subunit alpha type-1, putative 5.0
25994 PF3D7_0727400
proteasome subunit alpha type-5, putative 5.0
26076 PF3D7_1410400
rhoptry-associated protein 1 5.0
26040 PF3D7_1132200 T-complex protein 1 subunit alpha 5.0
25965 PF3D7_0308200 T-complex protein 1 subunit eta 5.0
26066 PF3D7_1357800
T-complex protein 1 subunit delta, tcp-1-delta 5.0
26025 PF3D7_1103100
60S acidic ribosomal protein P1, putative 4.5
26007 PF3D7_0922200
S-adenosylmethionine synthetase 4.5
26005 PF3D7_0917900
heat shock protein 70 4.2
26015 PF3D7_1011400
proteasome subunit beta type-5 4.0
26025 PF3D7_1103100
60S acidic ribosomal protein P1, putative 4.0
25993 PF3D7_0722400 OBG-like ATPase 1, putative 4.0
25967 PF3D7_0319600 elongation factor 1-delta, putative 4.0
25991 PF3D7_0716800 eukaryotic translation initiation factor 3 subunit I, putative 4.0
26059 PF3D7_1344200 endoplasmic reticulum chaperone grp170 4.0
26077 PF3D7_1427900 leucine-rich repeat protein 4.0
25988 PF3D7_0627500
protein DJ-1 4.0
25977 PF3D7_0511800
inositol-3-phosphate synthase 4.0
26012 PF3D7_0931800
proteasome subunit beta type-6, putative 4.0
25981 PF3D7_0608500 proteasome subunit alpha type-2, putative 4.0
26064 PF3D7_1353900 proteasome subunit alpha type-7, putative 4.0
25968 PF3D7_0320300 T-complex protein 1 subunit epsilon 4.0
25982 PF3D7_0608800
ornithine aminotransferase 4.0
25961 PF3D7_0220200 Plasmodium exported protein, unknown function 4.0
26016 PF3D7_1012400
hypoxanthine-guanine phosphoribosyltransferase 4.0
26046 PF3D7_1211800 polyubiquitin 3.8
25963 PF3D7_0306900 40S ribosomal protein S23, putative 3.5
26055 PF3D7_1324900
L-lactate dehydrogenase 3.4
26088 PF3D7_1471100
exported protein 2 3.3
25960 PF3D7_0219400
ribosome associated membrane protein RAMP4, putative 3.2
25979 PF3D7_0516900 60S ribosomal protein L2 3.1
25970 PF3D7_0413600
26S protease regulatory subunit 6B, putative; 26S proteasome AAA-ATPase subunit RPT3 3.0
25997 PF3D7_0816600
chaperone protein ClpB1 3.0
25969 PF3D7_0322000
peptidyl-prolyl cis-trans isomerase 3.0
26050 PF3D7_1247400
peptidyl-prolyl cis-trans isomerase fkbp 3.0
26006 PF3D7_0918000
glideosome-associated protein 50 secreted acid phosphatase 3.0
25984 PF3D7_0621800 nascent polypeptide-associated complex subunit alpha, putative 3.0
25992 PF3D7_0718500 prefoldin subunit 3, putative 3.0
26042 PF3D7_1134100
protein disulfide isomerase, putative 3.0
26067 PF3D7_1357900 pyrroline-5-carboxylate reductase, putative 3.0
25958 PF3D7_0207600
serine repeat antigen 5 3.0
26070 PF3D7_1367000 suppressor of kinetochore protein 1, putative 3.0
26002 PF3D7_0903700
alpha tubulin 1 3.0
26054 PF3D7_1317800 40S ribosomal protein S19 2.0
26028 PF3D7_1110700 actin-like protein, putative 2.0
25996 PF3D7_0815600 eukaryotic translation initiation factor 3 subunit G, putative 2.0
25973 PF3D7_0501100
co-chaperone j domain protein jdp 2.0
26037 PF3D7_1123900
13 kda ribonucleoprotein-associated protein, putative 2.0
26032 PF3D7_1116000
rhoptry neck protein 4 2.0
26056 PF3D7_1332800 eukaryotic translation initiation factor 6, putative 2.0
25962 PF3D7_0302500
cytoadherence linked asexual protein 3.1 1.0
26003 PF3D7_0905400
high molecular weight rhoptry protein 3 1.0
26080 PF3D7_1437900
HSP40, subfamily A 1.0
25972 PF3D7_0423800
RH5-Ripr membrane anchoring protein cysteine-rich protective antigen 1.0
34053 PF3D7_1461400
morn repeat protein, putative 1.0
26057 PF3D7_1335100
merozoite surface protein 7 1.0
25975 PF3D7_0501600
rhoptry-associated protein 2 1.0
25974 PF3D7_0501500
rhoptry-associated protein 3 1.0
26079 PF3D7_1437200
ribonucleoside-diphosphate reductase large subunit, putative 1.0
26014 PF3D7_1008700
tubulin beta chain 1.0
Online articles related to Highest expressed genes based on mRNA abundance retrieved from PubMed