|
Effect of hyperoxia on gene expression |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Torrentino-Madamet M, Alméras L, Desplans J, Le Priol Y, Belghazi M, Pophillat M, Fourquet P, Jammes Y, Parzy D. Global response of Plasmodium falciparum to hyperoxia: a combined transcriptomic and proteomic approach. Malar J. 2011 Jan 11;10:4. PMID: 21223545; |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
PfID |
|
|
Annotation |
% change |
EC |
Transcript |
Functional category |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
33361 |
PF3D7_1230200 |
|
|
vacuolar transporter chaperone, putative, pseudogene |
35.98 |
2.7.1.151 |
|
Intracellular traffic |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
33355 |
PF3D7_1210900 |
|
|
GPI mannosyltransferase I |
31.66 |
2.4.1.83 |
|
Lipid metabolism |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
33285 |
PF3D7_0308000 |
|
|
DNA polymerase delta small subunit, putative |
31.33 |
2.7.7.7 |
|
DNA metabolism |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
33311 |
PF3D7_0725000 |
|
|
exonuclease I, putative |
26.88 |
3.1.16.1 |
|
DNA metabolism |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
33328 |
PF3D7_1004400 |
|
|
RNA-binding protein, putative |
26.80 |
|
|
RNA metabolism |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
33339 |
PF3D7_1034600 |
|
|
translation initiation factor IF-3, putative |
24.11 |
|
|
Translation |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
33286 |
PF3D7_0311600 |
|
|
dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit ost1, putative |
22.35 |
2.4.99.18 |
|
Lipid metabolism |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
PF07_0131 |
|
|
|
22.19 |
|
|
Protein export |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
33343 |
PF3D7_1111100 |
|
|
replication factor C subunit 5, putative |
21.73 |
|
|
DNA metabolism |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
33337 |
PF3D7_1028400 |
|
|
ribosome biogenesis protein rpf2, putative |
21.36 |
|
|
Translation |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
33308 |
PF3D7_0715600 |
|
|
GTP-binding translation elongation factor tu family protein, putative |
21.07 |
|
|
Translation |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
33372 |
PF3D7_1309400 |
|
|
HORMA domain protein, putative |
20.93 |
|
|
Chromosome structure |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
33404 |
PF3D7_1435700 |
|
|
ataxin-2 like protein, putative |
20.35 |
|
|
Post translational modification |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
33296 |
PF3D7_0504000 |
|
|
cation transporting P-ATPase, ATPase3 |
17.36 |
3.6.3.12 |
|
Transport |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
33353 |
PF3D7_1206500 |
|
|
Tat binding protein 1(TBP-1)-interacting protein, putative |
17.17 |
|
|
Post translational modification |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
33306 |
PF3D7_0708800 |
|
|
PfHsp70-z |
17.08 |
|
|
Post translational modification |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
33344 |
PF3D7_1122900 |
|
|
dynein heavy chain, putative |
16.71 |
|
|
Invasion and motility |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
33351 |
PF3D7_1201400 |
|
|
Plasmodium exported protein, unknown function |
16.48 |
|
|
Protein export |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
33303 |
PF3D7_0628800 |
|
|
glutamyl-tRNA(Gln) amidotransferase subunit B, putative |
16.43 |
6.3.5.7 |
|
Translation |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
33312 |
PF3D7_0730100 |
|
|
tRNA pseudouridine synthase D, putative |
16.41 |
5.4.99.12 |
|
RNA metabolism |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
33304 |
PF3D7_0628900 |
|
|
RAP protein, putative |
15.30 |
|
|
Unknown function |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
33406 |
PF3D7_1437900 |
|
|
HSP40, subfamily A |
15.26 |
|
|
Post translational modification |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
33936 |
PF3D7_1249900 |
|
|
ribosomal RNA small subunit methyltransferase a2, putative |
14.97 |
|
|
Organellar functions |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
33402 |
PF3D7_1431800 |
|
|
apyrase |
14.44 |
3.6.1.5 |
|
Nucleotide metabolism |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
33309 |
PF3D7_0719200 |
|
|
NIMA related kinase 4 |
14.04 |
2.7.11.1 |
|
Post translational modification |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
33398 |
PF3D7_1411400 |
|
|
plastid replication-repair enzyme |
14.02 |
2.7.7.7 |
|
Organellar functions |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
33301 |
PF3D7_0607800 |
|
|
GTP-binding protein, putative |
13.83 |
|
|
Intracellular traffic |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
33380 |
PF3D7_1334300 |
|
|
MSP7-like protein |
13.68 |
|
|
Invasion and motility |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
33379 |
PF3D7_1330800 |
|
|
RNA-binding protein, putative |
13.37 |
|
|
RNA metabolism |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
33280 |
PF3D7_0212000 |
|
|
GDP-fructose:GMP antiporter, putative |
12.90 |
|
|
Transport |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
33407 |
PF3D7_1443400 |
|
|
WD repeat-containing protein, putative |
12.35 |
|
|
Unknown function |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
33274 |
PF3D7_0111400 |
|
|
conserved Plasmodium protein, unknown function gametocyte exported protein 19 |
12.28 |
|
|
Protein export |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
33396 |
PF3D7_1405400 |
|
|
DNA mismatch repair protein, putative |
12.27 |
|
|
DNA metabolism |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
33325 |
PF3D7_0930200 |
|
|
leucine-rich repeat protein |
12.17 |
|
|
Unknown function |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
33403 |
PF3D7_1434300 |
|
|
Hsp70/Hsp90 organizing protein |
12.07 |
|
|
Post translational modification |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
33302 |
PF3D7_0612300 |
|
|
transmembrane protein 234, putative |
12.00 |
|
|
Unknown function |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
33371 |
PF3D7_1307300 |
|
|
ATP-dependent RNA helicase dbp6 |
11.62 |
3.6.4.13 |
|
RNA metabolism |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
33376 |
PF3D7_1319100 |
|
|
ubiquitin carboxyl-terminal hydrolase mindy, putative |
11.36 |
3.4.19.12 |
|
Post translational modification |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
33340 |
PF3D7_1035000 |
|
|
U2 snRNA/tRNA pseudouridine synthase, putative |
11.24 |
5.4.99.12 |
|
RNA metabolism |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
33400 |
PF3D7_1416200 |
|
|
metacaspase-3, putative |
11.10 |
|
|
Post translational modification |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
33324 |
PF3D7_0928800 |
|
|
serine/threonine protein kinase, putative |
10.65 |
2.7.11.1 |
|
Post translational modification |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
33299 |
PF3D7_0524800 |
|
|
ubiquitin fusion degradation protein 1, putative |
10.46 |
|
|
Post translational modification |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
33374 |
PF3D7_1313400 |
|
|
DEAD box helicase, putative |
10.36 |
3.6.1.3 |
|
DNA metabolism |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
33384 |
PF3D7_1351600 |
|
|
glycerol kinase |
10.25 |
2.7.1.30 |
|
Carbohydrate metabolism |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
33334 |
PF3D7_1020800 |
|
|
dihydrolipoamide acyltransferase component E2 |
10.12 |
2.3.1.12 |
|
Organellar functions |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
33287 |
PF3D7_0316300 |
|
|
inorganic pyrophosphatase |
10.06 |
3.6.1.1 |
|
Lipid metabolism |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
33364 |
PF3D7_1241700 |
|
|
replication factor C subunit 4, putative |
9.94 |
|
|
DNA metabolism |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
33289 |
PF3D7_0413900 |
|
|
ubiquitin carboxyl-terminal hydrolase 13, putative |
9.93 |
3.4.19.12 |
|
Post translational modification |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
33357 |
PF3D7_1221400 |
|
|
inner membrane complex protein 1h, putative |
9.77 |
|
|
Invasion and motility |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
33392 |
PF3D7_1360500 |
|
|
guanylyl cyclase beta |
9.73 |
4.6.1.2 |
|
Nucleotide metabolism |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
33352 |
PF3D7_1203000 |
|
|
origin recognition complex subunit 1 |
9.47 |
|
|
DNA metabolism |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
33284 |
PF3D7_0306400 |
|
|
FAD-dependent glycerol-3-phosphate dehydrogenase, putative |
9.36 |
1.1.5.3 |
|
Carbohydrate metabolism |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
33300 |
PF3D7_0525500 |
|
|
WD repeat-containing protein, putative |
8.87 |
|
|
Unknown function |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
33295 |
PF3D7_0502000 |
|
|
vacuolar protein sorting-associated protein 11, putative |
8.35 |
|
|
Intracellular traffic |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
33397 |
PF3D7_1410900 |
|
|
ribosome maturation protein SBDS, putative |
8.30 |
|
|
Translation |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
33336 |
PF3D7_1027300 |
|
|
peroxiredoxin merozoite capping protein 1 |
7.97 |
1.11.1.15 |
|
Redox metabolism |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
33394 |
PF3D7_1366500 |
|
|
nucleoside diphosphate kinase |
7.77 |
2.7.4.6 |
|
Nucleotide metabolism |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
33350 |
PF3D7_1147700 |
|
|
ATP synthase subunit delta, mitochondrial, putative |
7.73 |
3.6.3.14 |
|
Organellar functions |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
33373 |
PF3D7_1311400 |
|
|
AP-1 complex subunit mu-1 |
7.37 |
|
|
Intracellular traffic |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
33272 |
PF3D7_0109000 |
|
|
photosensitized INA-labeled protein PHIL1 |
7.02 |
|
|
Invasion and motility |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
33358 |
PF3D7_1224000 |
|
|
GTP cyclohydrolase I |
6.96 |
3.5.4.16 |
|
Nucleotide metabolism |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
33332 |
PF3D7_1020400 |
|
|
rRNA(cytosine-c(5))-methyltransferase, putative |
6.51 |
2.1.1.12 |
|
RNA metabolism |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
33327 |
PF3D7_1003800 |
|
|
U5 small nuclear ribonucleoprotein component, putative |
6.40 |
|
|
RNA metabolism |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
33333 |
PF3D7_1020500 |
|
|
ribosomal silencing factor rsfs, putative |
6.11 |
|
|
Translation |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
33405 |
PF3D7_1437200 |
|
|
ribonucleoside-diphosphate reductase large subunit, putative |
5.75 |
1.17.4.1 |
|
Nucleotide metabolism |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
33401 |
PF3D7_1420400 |
|
|
glycine--tRNA ligase |
5.40 |
6.1.1.14 |
|
Translation |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
33305 |
PF3D7_0702000 |
|
|
Plasmodium exported protein (hyp12), unknown function |
5.32 |
|
|
Protein export |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
33375 |
PF3D7_1315900 |
|
|
exportin-T, putative |
5.07 |
|
|
Transport |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
33291 |
PF3D7_0423100 |
|
|
AP-4 complex subunit sigma, putative |
3.93 |
|
|
Intracellular traffic |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
33395 |
PF3D7_1401300 |
|
|
proline aminopeptidase |
-3.53 |
3.4.11.5 |
|
Amino acid metabolism |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
33288 |
PF3D7_0324700 |
|
|
erythrocyte membrane protein 1 (PfEMP1), exon 2, pseudogene |
-5.21 |
|
|
Protein export |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
33331 |
PF3D7_1017500 |
|
|
myosin essential light chain ELC |
-5.65 |
|
|
Invasion and motility |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
33411 |
PF3D7_1465800 |
|
|
dynein beta chain, putative |
-6.21 |
|
|
Invasion and motility |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
33385 |
PF3D7_1352100 |
|
|
ABC transporter B family member 6, putative, ABCB6 |
-7.37 |
|
|
Transport |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
33320 |
PF3D7_0913500 |
|
|
apicoplast-minus ipp-rescued 4 |
-8.12 |
|
|
Post translational modification |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
33368 |
PF3D7_1303500 |
|
|
sodium/hydrogen exchanger, Na+, H+ antiporter NHE |
-8.17 |
|
|
Transport |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
33335 |
PF3D7_1022600 |
|
|
kelch protein K10 |
-8.87 |
|
|
Post translational modification |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
33329 |
PF3D7_1009000 |
|
|
diphthine methyl ester synthase, putative |
-8.94 |
2.1.1.314 |
|
Post translational modification |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
33410 |
PF3D7_1453400 |
|
|
gamma-tubulin complex component, putative |
-9.73 |
|
|
Invasion and motility |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
33330 |
PF3D7_1014400 |
|
|
MO15-related protein kinase |
-9.73 |
2.7.11.22 |
|
DNA metabolism |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
33399 |
PF3D7_1413800 |
|
|
diphthamide biosynthesis protein 1, putative |
-9.92 |
6.3.2.22 |
|
Post translational modification |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
33338 |
PF3D7_1030200 |
|
|
claudin-like apicomplexan microneme protein |
-10.04 |
|
|
Invasion and motility |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
33386 |
PF3D7_1352200 |
|
|
U3 small nucleolar RNA-associated protein 15, putative |
-10.19 |
|
|
RNA metabolism |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
33276 |
PF3D7_0201600 |
|
|
PHISTb domain-containing RESA-like protein 1 |
-10.36 |
|
|
Protein export |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
33322 |
PF3D7_0918900 |
|
|
gamma-glutamylcysteine synthetase |
-10.37 |
6.3.2.2 |
|
Redox metabolism |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
33389 |
PF3D7_1355300 |
|
|
histone-lysine N-methyltransferase, putative |
-10.44 |
2.1.1.43 |
|
Histone modifications |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
33314 |
PF3D7_0821100 |
|
|
protein kinase 1 |
-10.56 |
2.7.11.1 |
|
Post translational modification |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
33378 |
PF3D7_1330000 |
|
|
pith domain-containing protein, putative |
-10.91 |
|
|
Post translational modification |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
33297 |
PF3D7_0511300 |
|
|
MORN repeat protein, putative |
-10.93 |
|
|
Post translational modification |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
33408 |
PF3D7_1445100 |
|
|
histidine--tRNA ligase, putative |
-10.98 |
6.1.1.21 |
|
Translation |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
33356 |
PF3D7_1218600 |
|
|
arginine-tRNA ligase; arginyl-tRNA synthetase |
-11.61 |
6.1.1.19 |
|
Translation |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
33292 |
PF3D7_0423500 |
|
|
glideosome associated protein with multiple membrane spans 2 |
-11.72 |
|
|
Invasion and motility |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
33377 |
PF3D7_1325000 |
|
|
U6 snRNA-associated Sm-like protein LSm6, putative |
-11.95 |
|
|
RNA metabolism |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
33323 |
PF3D7_0926100 |
|
|
protein kinase, putative |
-12.90 |
2.7.11.1 |
|
Post translational modification |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
33346 |
PF3D7_1127000 |
|
|
protein phosphatase, putative |
-12.91 |
3.1.3.16 |
|
Post translational modification |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
33342 |
PF3D7_1104200 |
|
|
chromatin remodeling protein |
-13.18 |
|
|
Histone modifications |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
33362 |
PF3D7_1231600 |
|
|
pre-mRNA-splicing factor ATP-dependent RNA helicase PRP2, putative |
-13.23 |
3.6.4.13 |
|
RNA metabolism |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
33391 |
PF3D7_1357700 |
|
|
U3 small nucleolar RNA-associated protein 21, putative |
-13.63 |
|
|
RNA metabolism |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
33348 |
PF3D7_1138100 |
|
|
ubiquitin-related modifier 1, putative |
-14.31 |
|
|
Post translational modification |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
33319 |
PF3D7_0909300 |
|
|
apoptosis-related protein |
-14.46 |
|
|
Post translational modification |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
33313 |
PF3D7_0815600 |
|
|
eukaryotic translation initiation factor 3 subunit G, putative |
-14.53 |
|
|
Translation |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
33307 |
PF3D7_0712600 |
|
|
erythrocyte membrane protein 1, PfEMP1 |
-14.55 |
|
|
Protein export |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
33321 |
PF3D7_0914600 |
|
|
transcription elongation factor 1, putative |
-15.28 |
|
|
RNA metabolism |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
33383 |
PF3D7_1341900 |
|
|
V-type proton ATPase subunit D, putative |
-15.41 |
3.6.3.14 |
|
Transport |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
33367 |
PF3D7_1301900 |
|
|
Plasmodium exported protein, unknown function |
-15.45 |
|
|
Protein export |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
33345 |
PF3D7_1125800 |
|
|
kelch domain-containing protein, putative |
-15.90 |
|
|
Unknown function |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
33298 |
PF3D7_0523400 |
|
|
DnaJ protein, putative |
-15.93 |
|
|
Post translational modification |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
33409 |
PF3D7_1447300 |
|
|
mitochondrial ribosomal protein S14 precursor, putative |
-16.40 |
|
|
Organellar functions |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
33279 |
PF3D7_0208000 |
|
|
serine repeat antigen 1 |
-16.67 |
3.4.22.- |
|
Post translational modification |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
33363 |
PF3D7_1237800 |
|
|
ubiquitin-like modifier HUB1, putative |
-16.72 |
|
|
Post translational modification |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
33360 |
PF3D7_1229800 |
|
|
myosin J |
-17.24 |
|
|
Invasion and motility |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
33317 |
PF3D7_0902500 |
|
|
serine/threonine protein kinase, FIKK family |
-17.29 |
2.7.11.1 |
|
Post translational modification |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
33393 |
PF3D7_1361400 |
|
|
actin-depolymerizing factor 2 |
-17.34 |
|
|
Invasion and motility |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
33354 |
PF3D7_1207100 |
|
|
pre-rRNA-processing protein esf1, putative |
-17.60 |
|
|
RNA metabolism |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
33369 |
PF3D7_1305400 |
|
|
AAR2 protein, putative |
-17.79 |
|
|
RNA metabolism |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
33390 |
PF3D7_1355700 |
|
|
NLI interacting factor-like phosphatase, putative |
-18.11 |
3.1.3.16 |
|
Post translational modification |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
33952 |
PF3D7_1353200 |
|
|
membrane associated histidine-rich protein 2 |
-18.45 |
|
|
Protein export |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
33277 |
PF3D7_0207000 |
|
|
merozoite surface protein 4 |
-18.56 |
|
|
Invasion and motility |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
33278 |
PF3D7_0207500 |
|
|
serine repeat antigen 6 |
-18.88 |
3.4.22.- |
|
Invasion and motility |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
33326 |
PF3D7_0936800 |
|
|
Plasmodium exported protein (PHISTc), unknown function |
-19.34 |
|
|
Protein export |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
33318 |
PF3D7_0904700 |
|
|
bacterial histone-like protein |
-19.52 |
|
|
Histone modifications |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
33283 |
PF3D7_0301300 |
|
|
epoxide hydrolase 1 |
-19.73 |
|
|
Protein export |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
33315 |
PF3D7_0822300 |
|
|
small nuclear ribonucleoprotein G, putative |
-20.22 |
|
|
RNA metabolism |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
33388 |
PF3D7_1355200 |
|
|
RAP protein, putative |
-21.11 |
|
|
Unknown function |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
33347 |
PF3D7_1137100 |
|
|
ribosomal protein s9, mitochondrial, putative |
-21.15 |
|
|
Organellar functions |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
33275 |
PF3D7_0111500 |
|
|
UMP-CMP kinase, putative |
-21.52 |
2.7.4.14 |
|
Nucleotide metabolism |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
33294 |
PF3D7_0501700 |
|
|
anaphase-promoting complex subunit 3, putative |
-22.56 |
|
|
Chromosome structure |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
33349 |
PF3D7_1141600 |
|
|
dolichol-phosphate mannosyltransferase |
-22.61 |
2.4.1.83 |
|
Lipid metabolism |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
33281 |
PF3D7_0212600 |
|
|
secreted protein with altered thrombospondin repeat domain |
-22.92 |
|
|
Protein export |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
33365 |
PF3D7_1248000 |
|
|
tRNA-splicing endonuclease, putative |
-24.69 |
4.6.1.16 |
|
RNA metabolism |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
33381 |
PF3D7_1334600 |
|
|
MSP7-like protein |
-24.76 |
|
|
Invasion and motility |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
33282 |
PF3D7_0220800 |
|
|
cytoadherence linked asexual protein 2 |
-26.61 |
|
|
cytoad |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
33359 |
PF3D7_1227900 |
|
|
RNA pseudouridylate synthase, putative |
-27.71 |
4.2.1.70 |
|
RNA metabolism |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
33310 |
PF3D7_0720700 |
|
|
phosphoinositide-binding protein px1 |
-28.44 |
|
|
Lipid metabolism |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
33273 |
PF3D7_0109600 |
|
|
cold-shock protein, putative |
-29.73 |
|
|
Post translational modification |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
33290 |
PF3D7_0414900 |
|
|
armadillo-domain containing rhoptry protein |
-30.80 |
|
|
Invasion and motility |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
33316 |
PF3D7_0902200 |
|
|
serine/threonine protein kinase, FIKK family |
-30.92 |
2.7.11.1 |
|
Post translational modification |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
33293 |
PF3D7_0424300 |
|
|
erythrocyte binding antigen-165, pseudogene |
-33.55 |
|
|
Invasion and motility |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
33341 |
PF3D7_1036000 |
|
|
merozoite surface protein 11 |
-35.16 |
|
|
Invasion and motility |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
33412 |
PF3D7_1475000 |
|
|
mediator of RNA polymerase ii transcription subunit 31, putative |
-39.54 |
|
|
RNA metabolism |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
33370 |
PF3D7_1306800 |
|
|
RED-like protein, putative |
-39.73 |
|
|
Unknown function |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
33382 |
PF3D7_1335100 |
|
|
merozoite surface protein 7 |
-44.15 |
|
|
Invasion and motility |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
+72 conserved Plasmodium protein, unknown function |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|