Malaria Parasite Metabolic Pathways
Drugs affecting pathway with unknown specific target
| Drug Name | PubMed Articles (year of publication) |
|---|---|
| 4-(2-methyl-2-(4-(1-((1r,5R,7S)-spiro[adamantane-2,3'-[1,2,4]trioxan]-6'-yl)vinyl)phenoxy)propoxy)-4-oxobutanoic acid | |
| Artesunate | |
| pumilacidin C |
Import of proteins into the mitochondrion map details
| PFID | PFID Old | Annotation | Formal Annotation | EC | Transcript |
|---|---|---|---|---|---|
PF3D7_1215300
|
PFL0740c | Cpn10 | 10 kDa chaperonin |
|
|
|
PF3D7_1333000
|
PF13_0180 | Cpn20 | 20 kDa chaperonin |
|
|
PF3D7_1124700
|
PF11_0258 | GrpE | GrpE protein homolog, mitochondrial, putative |
|
|
| PF3D7_1420300 | PF14_0197 | Hep1 | DNL-type zinc finger protein; hsp70-escort protein 1 |
|
|
|
PF3D7_0818900
|
PF08_0054 | Hsp70 | PfHsp70-1 |
|
|
|
PF3D7_0831700
|
MAL7P1.228 | Hsp70 | PfHsp70-x |
|
|
|
PF3D7_1134000
|
PF11_0351 | Hsp70 | PfHsp70-3 |
|
|
| PF3D7_1320400 | PF13_0118 | Imp1 | type I signal peptidase | 3.4.21.89 |
|
| PF3D7_1337000 | MAL13P1.184 | MIP | mitochondrial intermediate peptidase, putative | 3.4.24.59 |
|
| PF3D7_0523100 | PFE1155c | MPP | cytochrome b-c1 complex subunit 2, putative | 3.4.24.64 |
|
|
PF3D7_0933600
|
PFI1625c | MPP | cytochrome b-c1 complex subunit 1, putative | 3.4.24.64 |
|
| PF3D7_0828400 | MAL8P1.14 | Oxa | mitochondrial inner membrane protein OXA1, putative |
|
|
| PF3D7_0502200 | PFE0110w | protein mpv17 | protein mpv17, putative |
|
|
| PF3D7_0611100 | PFF0545c | Sdh3 | succinate dehydrogenase subunit 3, putative | 1.3.5.1 | |
| PF3D7_1208600 | PFL0430w | TIM10 | mitochondrial import inner membrane translocase subunit TIM10, putative |
|
|
| PF3D7_0502900 | PFE0140c | TIM10/ddp family zinc finger protein, putative | TIM10/ddp family zinc finger protein, putative |
|
|
| PF3D7_1242900 | PFL2065c | TIM13 | mitochondrial import inner membrane translocase subunit TIM13, putative | ||
| PF3D7_0724400 | PF07_0103 | TIM14 | mitochondrial import inner membrane translocase subunit TIM14, putative |
|
|
| PF3D7_0513500 | PFE0670w | TIM16 | mitochondrial import inner membrane translocase subunit TIM16, putative |
|
|
| PF3D7_1434700 | PF14_0328 | TIM17 | mitochondrial import inner membrane translocase subunit TIM17, putative |
|
|
| PF3D7_1420300 | PF14_0197 | TIM18 | DNL-type zinc finger protein; hsp70-escort protein 1 |
|
|
| PF3D7_0627400 | PFF1330c | TIM22 | mitochondrial import inner membrane translocase subunit TIM22, putative |
|
|
| PF3D7_1356200 | PF13_0300 | TIM23 | mitochondrial import inner membrane translocase subunit TIM23, putative |
|
|
| PF3D7_1125400 | PF11_0265 | TIM44 | mitochondrial import inner membrane translocase subunit TIM44, putative |
|
|
| PF3D7_0726900 | PF07_0110 | TIM50 | mitochondrial import inner membrane translocase subunit TIM50, putative | ||
| PF3D7_1421500 | PF14_0208 | TIM8 | mitochondrial import inner membrane translocase subunit TIM8, putative |
|
|
| PF3D7_1368600 | PF13_0358 | TIM9 | mitochondrial import inner membrane translocase subunit TIM9, putative |
|
|
| PF3D7_1145600 | PF11_0467 | TMEM65 | TMEM65 domain-containing protein, putative |
|
|
|
PF3D7_0524700
|
PFE1230c | TOM22 | mitochondrial import receptor subunit TOM22, putative |
|
|
|
PF3D7_0617000
|
PFF0825c | TOM40 | mitochondrial import receptor subunit TOM40, putative | ||
| PF3D7_0823700 | MAL8P1.36 | TOM7 | mitochondrial import receptor subunit TOM7, putative |
|
Total number of related proteins: 1
| # | PFID | Formal Name |
|---|---|---|
| 1 | PFE0110w | protein mpv17, putative |
Total number of related proteins: 1
| # | PFID | Formal Name |
|---|---|---|
| 1 | PFE0140c | TIM10/ddp family zinc finger protein, putative |
Total number of related proteins: 1
| # | PFID | Formal Name |
|---|---|---|
| 1 | PFE0670w | mitochondrial import inner membrane translocase subunit TIM16, putative |
Total number of related proteins: 2
| # | PFID | Formal Name |
|---|---|---|
| 1 | PFE1155c | cytochrome b-c1 complex subunit 2, putative |
| 2 |
PFI1625c
|
cytochrome b-c1 complex subunit 1, putative |
Total number of related proteins: 1
| # | PFID | Formal Name |
|---|---|---|
| 1 |
PFE1230c
|
mitochondrial import receptor subunit TOM22, putative |
Total number of related proteins: 1
| # | PFID | Formal Name |
|---|---|---|
| 1 | PFF0545c | succinate dehydrogenase subunit 3, putative |
Total number of related proteins: 1
| # | PFID | Formal Name |
|---|---|---|
| 1 |
PFF0825c
|
mitochondrial import receptor subunit TOM40, putative |
Total number of related proteins: 1
| # | PFID | Formal Name |
|---|---|---|
| 1 | PFF1330c | mitochondrial import inner membrane translocase subunit TIM22, putative |
Total number of related proteins: 1
| # | PFID | Formal Name |
|---|---|---|
| 1 | PF07_0103 | mitochondrial import inner membrane translocase subunit TIM14, putative |
Total number of related proteins: 1
| # | PFID | Formal Name |
|---|---|---|
| 1 | PF07_0110 | mitochondrial import inner membrane translocase subunit TIM50, putative |
Total number of related proteins: 3
| # | PFID | Formal Name |
|---|---|---|
| 1 |
PF08_0054
|
PfHsp70-1 |
| 2 |
MAL7P1.228
|
PfHsp70-x |
| 3 |
PF11_0351
|
PfHsp70-3 |
Total number of related proteins: 1
| # | PFID | Formal Name |
|---|---|---|
| 1 | MAL8P1.36 | mitochondrial import receptor subunit TOM7, putative |
Total number of related proteins: 1
| # | PFID | Formal Name |
|---|---|---|
| 1 | MAL8P1.14 | mitochondrial inner membrane protein OXA1, putative |
Total number of related proteins: 1
| # | PFID | Formal Name |
|---|---|---|
| 1 |
PF11_0258
|
GrpE protein homolog, mitochondrial, putative |
Total number of related proteins: 1
| # | PFID | Formal Name |
|---|---|---|
| 1 | PF11_0265 | mitochondrial import inner membrane translocase subunit TIM44, putative |
Total number of related proteins: 1
| # | PFID | Formal Name |
|---|---|---|
| 1 | PF11_0467 | TMEM65 domain-containing protein, putative |
Total number of related proteins: 1
| # | PFID | Formal Name |
|---|---|---|
| 1 | PFL0430w | mitochondrial import inner membrane translocase subunit TIM10, putative |
Total number of related proteins: 1
| # | PFID | Formal Name |
|---|---|---|
| 1 |
PFL0740c
|
10 kDa chaperonin |
Total number of related proteins: 1
| # | PFID | Formal Name |
|---|---|---|
| 1 | PFL2065c | mitochondrial import inner membrane translocase subunit TIM13, putative |
Total number of related proteins: 1
| # | PFID | Formal Name |
|---|---|---|
| 1 | PF13_0118 | type I signal peptidase |
Total number of related proteins: 1
| # | PFID | Formal Name |
|---|---|---|
| 1 |
PF13_0180
|
20 kDa chaperonin |
Total number of related proteins: 1
| # | PFID | Formal Name |
|---|---|---|
| 1 | MAL13P1.184 | mitochondrial intermediate peptidase, putative |
Total number of related proteins: 1
| # | PFID | Formal Name |
|---|---|---|
| 1 | PF13_0300 | mitochondrial import inner membrane translocase subunit TIM23, putative |
Total number of related proteins: 1
| # | PFID | Formal Name |
|---|---|---|
| 1 | PF13_0358 | mitochondrial import inner membrane translocase subunit TIM9, putative |
Total number of related proteins: 1
| # | PFID | Formal Name |
|---|---|---|
| 1 | PF14_0197 | DNL-type zinc finger protein; hsp70-escort protein 1 |
Total number of related proteins: 1
| # | PFID | Formal Name |
|---|---|---|
| 1 | PF14_0197 | DNL-type zinc finger protein; hsp70-escort protein 1 |
Total number of related proteins: 1
| # | PFID | Formal Name |
|---|---|---|
| 1 | PF14_0208 | mitochondrial import inner membrane translocase subunit TIM8, putative |
Total number of related proteins: 1
| # | PFID | Formal Name |
|---|---|---|
| 1 | PF14_0328 | mitochondrial import inner membrane translocase subunit TIM17, putative |