idc:Reduced ferredoxin Ferredoxine reductase idc:Triose phosphate isomerase Reduced ferredoxin idc:Reduced ferredoxin idc:4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase idc:1-deoxy-D-xylulose-5-phosphate reductoisomerase 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase idc:1-deoxy-D-xylulose 5-phosphate synthase Pyruvate kinase idc:Triose-P/Pi translocator idc:PEP/Pi translocator idc:Ferredoxine reductase Ferredoxine reductase idc:Ferredoxine reductase Reduced ferredoxin Triose-P/Pi translocator PEP/Pi translocator idc:4-hydroxy-3-methylbut-2-enyl diphosphate reductase idc:2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase 1-deoxy-D-xylulose 5-phosphate synthase 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase idc:4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase 1-deoxy-D-xylulose-5-phosphate reductoisomerase idc:2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase Triose phosphate isomerase idc:Pyruvate kinase


Online articles related to Isoprenoids metabolism retrieved from PubMed

RX Drugs affecting pathway with unknown specific target

Drug Name PubMed Articles (year of publication)
[({4-[Hydroxy(methyl)amino]-4-oxobutyl}phosphoryl)bis (oxy)]bis(methylene) dioctanoate
[(4E)-1,5,9-trimethyl-1-vinyl-deca-4,8-dienyl]benzene
[2-benzoyl-4-[(4E)-1,5,9-trimethyl-1-vinyl-deca-4,8-dienyl]phenyl]-phenyl-methanone
[2-formyloxy-4-[(4E)-1,5,9-trimethyl-1-vinyl-deca-4,8-dienyl]phenyl] formate
1,2-dibenzyl-4-[(4E)-1,5,9-trimethyl-1-vinyl-deca-4,8-dienyl]benzene
1,2-o,o-diacetyl-4-nerolidylcatechol
Atorvastatin
Fluvastatin
fosmidomycin
Limonene
Lovastatin
Mevastatin
Mmv008138
MMV665915
MMV666600
Nerolidol
Pravastatin
Risedronate
Simvastatin
Squalestatin
Structure

Isoprenoids metabolism map details

PFID PFID Old Annotation Formal Annotation EC Transcript
PF3D7_1337200 drugs MAL13P1.186 1-deoxy-D-xylulose 5-phosphate synthase 1-deoxy-D-xylulose 5-phosphate synthase 2.2.1.7 pie diagram
PF3D7_1467300 loop drugs PF14_0641 1-deoxy-D-xylulose-5-phosphate reductoisomerase 1-deoxy-D-xylulose 5-phosphate reductoisomerase 1.1.1.267 pie diagram
PF3D7_0209300 drugs PFB0420w 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase 4.6.1.12 pie diagram
PF3D7_0106900 drugs PFA0340w 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, putative 2.7.7.60 pie diagram
PF3D7_0503100 loop drugs PFE0150c 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, putative 2.7.1.148 pie diagram
PF3D7_1022800 loop drugs PF10_0221 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (ferredoxin), putative 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (ferredoxin), putative 1.17.7.1 pie diagram
PF3D7_0104400 drugs PFA0225w 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 1.17.1.2 pie diagram
PF3D7_0623200 drugs PFF1115w Ferredoxine reductase ferredoxin--NADP reductase 1.18.1.2 pie diagram
PF3D7_0530200 loop PFE1510c PEP/Pi translocator phosphoenolpyruvate/phosphate translocator, PPT pie diagram
PF3D7_1037100 loop drugs PF10_0363 Pyruvate kinase pyruvate kinase 2, pyrkii 2.7.1.40 pie diagram
PF3D7_1318100 MAL13P1.95 Reduced ferredoxin ferredoxin, putative pie diagram
PF3D7_0318800 drugs PFC0831w Triose phosphate isomerase triosephosphate isomerase, putative 5.3.1.1 pie diagram
PF3D7_1439900 drugs PF14_0378 Triose phosphate isomerase triosephosphate isomerase 5.3.1.1 pie diagram
PF3D7_0508300 loop PFE0410w Triose-P/Pi translocator triose phosphate transporter, TPT pie diagram